Chang Xie, PhD

Yang Z, Lu D, Zhang L, Hu J, Nie Z, Xie C, Qiu F, Cheng H, Yan Y. p.N1380del mutation in the pore-forming region of SCN5A gene is associated with cardiac conduction disturbance and ventricular tachycardia. Volume 49 of Issue 3. 2017. PMID: 28159958

Xie C, Gong XM, Luo J, Li BL, Song BL. AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease. Volume 58 of Issue 3. Journal of lipid research 2017. PMID: 28053186

Xie C, Zhang YP, Song L, Luo J, Qi W, Hu J, Lu D, Yang Z, Zhang J, Xiao J, Zhou B, Du JL, Jing N, Liu Y, Wang Y, Li BL, Song BL, Yan Y. Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome. Volume 26 of Issue 10. 2016. PMID: 27573176

Zhang HL, Zheng YJ, Pan YD, Xie C, Sun H, Zhang YH, Yuan MY, Song BL, Chen JF. Regulatory T-cell depletion in the gut caused by integrin ß7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity. Volume 9 of Issue 2. 2015. PMID: 26220167

Chu BB, Liao YC, Qi W, Xie C, Du X, Wang J, Yang H, Miao HH, Li BL, Song BL. Cholesterol transport through lysosome-peroxisome membrane contacts. Volume 161 of Issue 2. 2015. PMID: 25860611

Xie C, Zhou ZS, Li N, Bian Y, Wang YJ, Wang LJ, Li BL, Song BL. Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine. Volume 53 of Issue 10. Journal of lipid research 2012. PMID: 22811412

Xie C, Li N, Chen ZJ, Li BL, Song BL. The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner. Volume 286 of Issue 41. The Journal of biological chemistry 2011. PMID: 21844200

Chu BB, Ge L, Xie C, Zhao Y, Miao HH, Wang J, Li BL, Song BL. Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface. Volume 284 of Issue 33. The Journal of biological chemistry 2009. PMID: 19542231