Carl Grunfeld, MD, PhD

Professor

Dr. Grunfeld’s research involves two major areas. He studies how infection and inflammation affect metabolism and body composition, with a focus on ways those changes promote atherosclerosis. He also studies how disease and therapy affect kidney function with laboratory studies looking at novel markers in urine and blood.
Education
2018 - Diversity, Equity, and Inclusion Champion Training, University of California
1980 - Endocrinology Fellowship, National Institutes of Health
1977 - Internal Medicine Residency, Massachuetts General Hospital
MD, 1975 - Medicine, Albert Einstein College of Medicine
PhD, 1974 - Phrarmacology, Albert Einstein College of Medicine
BS, 1968 - Biology, Haverford College
Honors and Awards
  • Certificate of Appreciation for Distinguished Service, Department of Veterans Affairs, 2019
  • John H. Karam, MD, Clinician Educator Award, Division of Endocrinology and Metabolism, UCSF, 2019
  • Distinguished Achievement Award for Outstanding Accomplishments in a Profession, Alumni Association, Haverford College, 2018
  • Alumni Lifetime Achievement Award, Albert Einstein College of Medicine, 2012
  • Office of Public Health Strategic Healthcare Group Award, Department of Veterans Affairs, 2010
  • The Endocrine Society and Pfizer Inc. International Award for Excellence in Published Clinical Res, Journal of Clinical Endocrinology & Metabolism, 2010
  • Robert H. Williams-Rachmiel Levine Award, Western Metabolism Club, 2010
  • Catharina Pijls Lecture, University of Maastricht, 1999
Publications

  1. Abelman RA, Schneider MF, Cox C, Messerlian G, Cohen M, Gustafson D, Plankey M, Sharma A, Price J, Grunfeld C, Tien PC. ASSOCIATION OF ANDROGEN HORMONES, SEX HORMONE BINDING GLOBULIN, AND THE MENOPAUSAL TRANSITION WITH INCIDENT DIABETES MELLITUS IN WOMEN WITH AND WITHOUT HIV. Journal of acquired immune deficiency syndromes (1999) 2024. PMID: 38180885


  2. Abelman RA, Nguyen TTJ, Ma Y, Bacchetti P, Messerlian G, French AL, Sharma A, Minkoff H, Plankey M, Grunfeld C, Tien PC. Body Composition Changes over the Menopausal Transition in Women With and Without HIV. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023. PMID: 36974507


  3. Kim TY, Schwartz AV, Li X, Xu K, Kazakia GJ, Grunfeld C, Nissenson RA, Shoback DM, Schafer AL. Bone marrow adipose tissue composition and glycemic improvements after gastric bypass surgery. Bone reports 2022. PMID: 35734226


  4. Keyhani S, Cohen BE, Vali M, Hoggatt KJ, Bravata DM, Austin PC, Lum E, Hasin DS, Grunfeld C, Shlipak MG. The Heart and Cannabis (THC) Cohort: Differences in Baseline Health and Behaviors by Cannabis Use. AACE Clinical Case Reports 2022. PMID: 35013928


  5. Seal KH, Bertenthal D, Carey E, Grunfeld C, Bikle DD, Lu CM. Association of Vitamin D Status and COVID-19-Related Hospitalization and Mortality. AACE Clinical Case Reports 2022. PMID: 34981368


  6. Muiru AN, Scherzer R, Ascher SB, Jotwani V, Grunfeld C, Shigenaga J, Spaulding KA, Ng DK, Gustafson D, Spence AB, Sharma A, Cohen MH, Parikh CR, Ix JH, Estrella MM, Shlipak MG. Associations of CKD risk factors and longitudinal changes in urine biomarkers of kidney tubules among women living with HIV. BMC nephrology 2021. PMID: 34461840


  7. Ascher SB, Scherzer R, Estrella MM, Muiru AN, Jotwani VK, Grunfeld C, Shigenaga J, Spaulding KA, Ng DK, Gustafson D, Spence AB, Sharma A, Cohen MH, Parikh CR, Ix JH, Shlipak MG. Kidney tubule health scores and their associations with incident CKD in women living with HIV. HIV medicine 2021. PMID: 33751761


  8. Cedarbaum E, Ma Y, Scherzer R, Price JC, Adimora AA, Bamman M, Cohen M, Fischl MA, Matsushita K, Ofotokun I, Plankey M, Seaberg EC, Yin MT, Grunfeld C, Vartanian S, Sharma A, Tien PC. Contributions of HIV, HCV, and traditional vascular risk factors to peripheral artery disease in women. AIDS (London, England) 2019. PMID: 31335806


  9. Ascher SB, Scherzer R, Nishtala A, Jotwani V, Grunfeld C, Parikh CR, Ng D, Wang R, Palella FJ, Shlipak MG, Estrella MM. Association of Statin Use with Kidney Damage and Function Among HIV-infected Men. Journal of acquired immune deficiency syndromes (1999) 2019. PMID: 31356467


  10. Feinstein MJ, Nance RM, Delaney JAC, Heckbert SR, Budoff MJ, Drozd DR, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Peter I, Lober WB, Crothers K, Grunfeld C, Saag MS, Kitahata MM, Lloyd-Jones DM, Crane HM. Mortality following myocardial infarction among HIV-infected persons: the Center for AIDS Research Network Of Integrated Clinical Systems (CNICS). BMC medicine 2019. PMID: 31362721


  11. Zhang WR, Scherzer R, Estrella MM, Ascher SB, Muiru A, Jotwani V, Grunfeld C, Parikh CR, Gustafson D, Kassaye S, Sharma A, Cohen M, Tien PC, Ng DK, Palella FJ, Witt MD, Ho K, Shlipak MG. Tenofovir disoproxil fumarate initiation and changes in urinary biomarker concentrations among HIV-infected men and women. AIDS (London, England) 2019. PMID: 30830887


  12. Zahner GJ, Ramirez JL, Spaulding KA, Khetani SA, Gasper WJ, Grunfeld C, Hills NK, Schafer AL, Grenon SM. Leptinemia is Associated With Peripheral Artery Disease. The Journal of surgical research 2019. PMID: 30738358


  13. Muiru AN, Shlipak MG, Scherzer R, Zhang WR, Ascher SB, Jotwani V, Grunfeld C, Parikh CR, Ng D, Palella FJ, Ho K, Kassaye S, Sharma A, Cohen M, Wang R, Qi Q, Estrella MM. Kidney disease risk factors associate with urine biomarkers concentrations in HIV-positive persons; a cross-sectional study. BMC nephrology 2019. PMID: 30606136


  14. Ascher SB, Scherzer R, Estrella MM, Zhang WR, Muiru AN, Jotwani V, Grunfeld C, Parikh CR, Gustafson D, Young M, Sharma A, Cohen MH, Ng DK, Palella FJ, Witt MD, Ho K, Shlipak MG. Association of Urinary Biomarkers of Kidney Injury with Estimated GFR Decline in HIV-Infected Individuals following Tenofovir Disoproxil Fumarate Initiation. Clinical journal of the American Society of Nephrology : CJASN 2018. PMID: 30154221


  15. Scherzer R, Shah SJ, Secemsky E, Butler J, Grunfeld C, Shlipak MG, Hsue PY. Association of Biomarker Clusters With Cardiac Phenotypes and Mortality in Patients With HIV Infection. Volume 11 of Issue 4. 2018. PMID: 29615435


  16. Reid M, Ma Y, Scherzer R, Price JC, French AL, Huhn GD, Plankey MW, Peters M, Grunfeld C, Tien PC. Contribution of Liver Fibrosis and Microbial Translocation to Immune Activation in Persons Infected With HIV and/or Hepatitis C Virus. Volume 217 of Issue 8. The Journal of infectious diseases 2018. PMID: 29304196


  17. Chau KH, Scherzer R, Grunfeld C, Hsue PY, Shlipak MG. CHA2DS2-VASc Score, Warfarin Use, and Risk for Thromboembolic Events Among HIV-Infected Persons With Atrial Fibrillation. Volume 76 of Issue 1. Journal of acquired immune deficiency syndromes (1999) 2017. PMID: 28797024


  18. Chen R, Scherzer R, Hsue PY, Jotwani V, Estrella MM, Horberg MA, Grunfeld C, Shlipak MG. Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients. Volume 6 of Issue 4. 2017. PMID: 28438737


  19. Crane HM, Paramsothy P, Drozd DR, Nance RM, Delaney JA, Heckbert SR, Budoff MJ, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Rodriguez C, Peter I, Barnes GS, McReynolds J, Lober WB, Crothers K, Feinstein MJ, Grunfeld C, Saag MS, Kitahata MM. Types of Myocardial Infarction Among Human Immunodeficiency Virus-Infected Individuals in the United States. Volume 2 of Issue 3. 2017. PMID: 28052152


  20. Noorhasan M, Drozd DR, Grunfeld C, Merrill JO, Burkholder GA, Mugavero MJ, Willig JH, Willig AL, Cropsey KL, Mayer KH, Blashill A, Mimiaga M, McCaul ME, Hutton H, Chander G, Mathews WC, Napravnik S, Eron JJ, Christopoulos K, Fredericksen RJ, Nance RM, Delaney JC, Crane PK, Saag MS, Kitahata MM, Crane HM. Associations Between At-Risk Alcohol Use, Substance Use, and Smoking with Lipohypertrophy and Lipoatrophy Among Patients Living with HIV. AIDS research and human retroviruses 2017. PMID: 28092168


  21. Reid M, Ma Y, Scherzer R, Price JC, French AL, Plankey MW, Grunfeld C, Tien PC. Higher CD163 levels are associated with insulin resistance in hepatitis C virus-infected and HIV-infected adults. Volume 31 of Issue 3. AIDS (London, England) 2017. PMID: 28081037


  22. Scherzer R, Heymsfield SB, Rimland D, Powderly WG, Tien PC, Bacchetti P, Shlipak MG, Grunfeld C. Association of serum albumin and aspartate transaminase with 5-year all-cause mortality in HIV/hepatitis C virus coinfection and HIV monoinfection. Volume 31 of Issue 1. AIDS (London, England) 2017. PMID: 27677166


  23. Ascher SB, Scherzer R, Peralta CA, Tien PC, Grunfeld C, Estrella MM, Abraham A, Gustafson DR, Nowicki M, Sharma A, Cohen MH, Butch AW, Young MA, Bennett MR, Shlipak MG. Association of Kidney Function and Early Kidney Injury With Incident Hypertension in HIV-Infected Women. Volume 69 of Issue 2. 2016. PMID: 27993956


  24. Feingold KR, Grunfeld C. Effect of inflammation on HDL structure and function. Volume 27 of Issue 5. 2016. PMID: 27495134


  25. Grunfeld C, Dankner R. Diabetes in HIV-infected persons in Cameroon? Volume 32 of Issue 6. 2016. PMID: 26936763


  26. Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY. HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". Volume 5 of Issue 5. 2016. PMID: 27130349


  27. Daubenmier J, Moran PJ, Kristeller J, Acree M, Bacchetti P, Kemeny ME, Dallman M, Lustig RH, Grunfeld C, Nixon DF, Milush JM, Goldman V, Laraia B, Laugero KD, Woodhouse L, Epel ES, Hecht FM. Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial. Volume 24 of Issue 4. 2016. PMID: 26955895


  28. Tuot DS, Scherzer R, Leong H, Hung AM, Grunfeld C, Shlipak MG. Use of cystatin C to inform metformin eligibility among adult veterans with diabetes. Volume 3. 2016. PMID: 28603691


  29. Swanson S, Ma Y, Scherzer R, Huhn G, French AL, Plankey MW, Grunfeld C, Rosenberg WM, Peters MG, Tien PC. Association of HIV, Hepatitis C Virus, and Liver Fibrosis Severity With the Enhanced Liver Fibrosis Score. Volume 213 of Issue 7. The Journal of infectious diseases 2015. PMID: 26621911


  30. Shah S, Ma Y, Scherzer R, Huhn G, French AL, Plankey M, Peters MG, Grunfeld C, Tien PC. Association of HIV, hepatitis C virus and liver fibrosis severity with interleukin-6 and C-reactive protein levels. Volume 29 of Issue 11. AIDS (London, England) 2015. PMID: 25870985


  31. Rao MN, Neylan TC, Grunfeld C, Mulligan K, Schambelan M, Schwarz JM. Subchronic sleep restriction causes tissue-specific insulin resistance. Volume 100 of Issue 4. 2015. PMID: 25658017


  32. Schafer AL, Li X, Schwartz AV, Tufts LS, Wheeler AL, Grunfeld C, Stewart L, Rogers SJ, Carter JT, Posselt AM, Black DM, Shoback DM. Changes in vertebral bone marrow fat and bone mass after gastric bypass surgery: A pilot study. Volume 74. 2015. PMID: 25603463


  33. Wheeler AL, Tien PC, Grunfeld C, Schafer AL. Teriparatide treatment of osteoporosis in an HIV-infected man: a case report and literature review. Volume 29 of Issue 2. AIDS (London, England) 2015. PMID: 25532609


  34. Zhi D, Shendre A, Scherzer R, Irvin MR, Perry RT, Levy S, Arnett DK, Grunfeld C, Shrestha S. Deep sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individuals. Volume 60 of Issue 2. 2014. PMID: 25500725


  35. O'Donovan A, Chao LL, Paulson J, Samuelson KW, Shigenaga JK, Grunfeld C, Weiner MW, Neylan TC. Altered inflammatory activity associated with reduced hippocampal volume and more severe posttraumatic stress symptoms in Gulf War veterans. Volume 51. 2014. PMID: 25465168


  36. Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J. Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. Volume 3 of Issue 5. 2014. PMID: 25336464


  37. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages. Volume 55 of Issue 12. Journal of lipid research 2014. PMID: 25320346


  38. Malkina A, Scherzer R, Shlipak MG, Bacchetti P, Tien PC, Grunfeld C, Kosmiski L, Peralta CA. The association of adiposity with kidney function decline among HIV-infected adults: findings from the Fat Redistribution and Metabolic Changes in HIV Infection (FRAM) study. HIV medicine 2014. PMID: 25251910


  39. Rao MN, Chau A, Madden E, Inslicht S, Talbot L, Richards A, O'Donovan A, Ruoff L, Grunfeld C, Neylan TC. Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder. Volume 49. 2014. PMID: 25108160


  40. Lang J, Scherzer R, Tien PC, Parikh CR, Anastos K, Estrella MM, Abraham AG, Sharma A, Cohen MH, Butch AW, Nowicki M, Grunfeld C, Shlipak MG. Serum albumin and kidney function decline in HIV-infected women. Volume 64 of Issue 4. American journal of kidney diseases : the official journal of the National Kidney Foundation 2014. PMID: 25059222


  41. Scherzer R, Gandhi M, Estrella MM, Tien PC, Deeks SG, Grunfeld C, Peralta CA, Shlipak MG. A chronic kidney disease risk score to determine tenofovir safety in a prospective cohort of HIV-positive male veterans. Volume 28 of Issue 9. AIDS (London, England) 2014. PMID: 24922479


  42. Pulliam L, Calosing C, Sun B, Grunfeld C, Rempel H. Monocyte activation from interferon-a in HIV infection increases acetylated LDL uptake and ROS production. Volume 34 of Issue 10. 2014. PMID: 24731171


  43. Manenschijn L, Scherzer R, Koper JW, Danoff A, van Rossum EF, Grunfeld C. Association of glucocorticoid receptor haplotypes with body composition and metabolic parameters in HIV-infected patients from the FRAM study. Volume 24 of Issue 3. 2014. PMID: 24418810


  44. Wheeler AL, Scherzer R, Lee D, Delaney JA, Bacchetti P, Shlipak MG, Sidney S, Grunfeld C, Tien PC. HIV/hepatitis C virus coinfection ameliorates the atherogenic lipoprotein abnormalities of HIV infection. Volume 28 of Issue 1. AIDS (London, England) 2014. PMID: 24136113


  45. Peralta C, Scherzer R, Grunfeld C, Abraham A, Tien P, Devarajan P, Bennett M, Butch A, Anastos K, Cohen M, Nowicki M, Sharma A, Young M, Sarnak M, Parikh C, Shlipak M. Urinary biomarkers of kidney injury are associated with all-cause mortality in the Women's Interagency HIV Study (WIHS). HIV medicine 2013. PMID: 24313986


  46. Shrestha S, Irvin MR, Grunfeld C, Arnett DK. HIV, inflammation, and calcium in atherosclerosis. Volume 34 of Issue 2. 2013. PMID: 24265418


  47. Jotwani V, Scherzer R, Abraham A, Estrella MM, Bennett M, Devarajan P, Anastos K, Cohen MH, Nowicki M, Sharma A, Young M, Tien PC, Grunfeld C, Parikh CR, Shlipak MG. Does HIV infection promote early kidney injury in women? Volume 19 of Issue 1. 2013. PMID: 23970313


  48. Maguen S, Madden E, Cohen B, Bertenthal D, Neylan T, Talbot L, Grunfeld C, Seal K. The relationship between body mass index and mental health among Iraq and Afghanistan veterans. Volume 28 Suppl 2. Journal of general internal medicine 2013. PMID: 23807066


  49. Lang J, Scherzer R, Weekley CC, Tien PC, Grunfeld C, Shlipak MG. Serum albumin and short-term risk for mortality and cardiovascular disease among HIV-infected veterans. Volume 27 of Issue 8. AIDS (London, England) 2013. PMID: 23343914


  50. Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue PY. Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals. Volume 229 of Issue 1. 2013. PMID: 23711612


  51. Hsu JC, Li Y, Marcus GM, Hsue PY, Scherzer R, Grunfeld C, Shlipak MG. Atrial fibrillation and atrial flutter in human immunodeficiency virus-infected persons: incidence, risk factors, and association with markers of HIV disease severity. Volume 61 of Issue 22. Journal of the American College of Cardiology 2013. PMID: 23563125


  52. Jiang YJ, Kim P, Uchida Y, Elias PM, Bikle DD, Grunfeld C, Feingold KR. Ceramides stimulate caspase-14 expression in human keratinocytes. Volume 22 of Issue 2. 2013. PMID: 23362869


  53. Shlipak MG, Scherzer R, Abraham A, Tien PC, Grunfeld C, Peralta CA, Devarajan P, Bennett M, Butch AW, Anastos K, Cohen MH, Nowicki M, Sharma A, Young MA, Sarnak MJ, Parikh CR. Urinary markers of kidney injury and kidney function decline in HIV-infected women. Volume 61 of Issue 5. Journal of acquired immune deficiency syndromes (1999) 2012. PMID: 23023103


  54. Feingold KR, Grunfeld C. Lipids: a key player in the battle between the host and microorganisms. Volume 53 of Issue 12. Journal of lipid research 2012. PMID: 23075464


  55. Feingold KR, Shigenaga JK, Kazemi MR, McDonald CM, Patzek SM, Cross AS, Moser A, Grunfeld C. Mechanisms of triglyceride accumulation in activated macrophages. Volume 92 of Issue 4. 2012. PMID: 22753953


  56. Feingold KR, Grunfeld C. Psoriasis: it's more than just the skin. Volume 53 of Issue 8. Journal of lipid research 2012. PMID: 22685321


  57. Scherzer R, Estrella M, Li Y, Choi AI, Deeks SG, Grunfeld C, Shlipak MG. Association of tenofovir exposure with kidney disease risk in HIV infection. Volume 26 of Issue 7. AIDS (London, England) 2012. PMID: 22313955


  58. Feingold KR, Shigenaga JK, Cross AS, Moser A, Grunfeld C. Angiopoietin like protein 4 expression is decreased in activated macrophages. Volume 421 of Issue 3. Biochemical and biophysical research communications 2012. PMID: 22538368


  59. Feingold KR, Grunfeld C, Heuer JG, Gupta A, Cramer M, Zhang T, Shigenaga JK, Patzek SM, Chan ZW, Moser A, Bina H, Kharitonenkov A. FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis. Volume 153 of Issue 6. 2012. PMID: 22474187


  60. Hsue PY, Scherzer R, Grunfeld C, Nordstrom SM, Schnell A, Kohl LP, Nitta E, Martin JN, Deeks SG, Weiss EJ. HIV infection is associated with decreased thrombin generation. Volume 54 of Issue 8. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012. PMID: 22438347


  61. Li Y, Shlipak MG, Grunfeld C, Choi AI. Incidence and risk factors for acute kidney injury in HIV Infection. Volume 35 of Issue 4. 2012. PMID: 22456100


  62. Shen W, Scherzer R, Gantz M, Chen J, Punyanitya M, Lewis CE, Grunfeld C. Relationship between MRI-measured bone marrow adipose tissue and hip and spine bone mineral density in African-American and Caucasian participants: the CARDIA study. Volume 97 of Issue 4. 2012. PMID: 22319043


  63. Jotwani V, Li Y, Grunfeld C, Choi AI, Shlipak MG. Risk factors for ESRD in HIV-infected individuals: traditional and HIV-related factors. Volume 59 of Issue 5. American journal of kidney diseases : the official journal of the National Kidney Foundation 2011. PMID: 22206742


  64. Irvin MR, Shrestha S, Chen YD, Wiener HW, Haritunians T, Vaughan LK, Tiwari HK, Taylor KD, Scherzer R, Saag MS, Grunfeld C, Rotter JI, Arnett DK. Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men. Volume 21 of Issue 12. 2011. PMID: 21897333


  65. Eastburn A, Scherzer R, Zolopa AR, Benson C, Tracy R, Do T, Bacchetti P, Shlipak M, Grunfeld C, Tien PC. Association of low level viremia with inflammation and mortality in HIV-infected adults. Volume 6 of Issue 11. PloS one 2011. PMID: 22073156


  66. Kosmiski LA, Scherzer R, Heymsfield SB, Rimland D, Simberkoff MS, Sidney S, Shlipak MG, Bacchetti P, Biggs ML, Grunfeld C. Association of increased upper trunk and decreased leg fat with 2-h glucose in control and HIV-infected persons. Volume 34 of Issue 11. Diabetes care 2011. PMID: 21926283


  67. Scherzer R, Heymsfield SB, Lee D, Powderly WG, Tien PC, Bacchetti P, Shlipak MG, Grunfeld C. Decreased limb muscle and increased central adiposity are associated with 5-year all-cause mortality in HIV infection. Volume 25 of Issue 11. AIDS (London, England) 2011. PMID: 21572308


  68. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation inhibits GPR81 expression in adipose tissue. Volume 60 of Issue 10. 2011. PMID: 21751047


  69. Lake JE, Wohl D, Scherzer R, Grunfeld C, Tien PC, Sidney S, Currier JS. Regional fat deposition and cardiovascular risk in HIV infection: the FRAM study. Volume 23 of Issue 8. AIDS care 2011. PMID: 21767228


  70. Jotwani V, Scherzer R, Choi A, Szczech L, Polak JF, Kronmal RA, Grunfeld C, Shlipak M. Reduced kidney function and preclinical atherosclerosis in HIV-infected individuals: the study of fat redistribution and metabolic change in HIV infection (FRAM). Volume 33 of Issue 5. 2011. PMID: 21508633


  71. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation inhibits the expression of phosphoenolpyruvate carboxykinase in liver and adipose tissue. Volume 18 of Issue 2. 2011. PMID: 21450790


  72. Rooney T, Scherzer R, Shigenaga JK, Graf J, Imboden JB, Grunfeld C. Levels of plasma fibrinogen are elevated in well-controlled rheumatoid arthritis. Volume 50 of Issue 8. 2011. PMID: 21441551


  73. Yarasheski KE, Scherzer R, Kotler DP, Dobs AS, Tien PC, Lewis CE, Kronmal RA, Heymsfield SB, Bacchetti P, Grunfeld C. Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals. Volume 66 of Issue 3. The journals of gerontology. Series A, Biological sciences and medical sciences 2011. PMID: 21310810


  74. Crane HM, Grunfeld C, Willig JH, Mugavero MJ, Van Rompaey S, Moore R, Rodriguez B, Feldman BJ, Lederman MM, Saag MS, Kitahata MM. Impact of NRTIs on lipid levels among a large HIV-infected cohort initiating antiretroviral therapy in clinical care. Volume 25 of Issue 2. AIDS (London, England) 2011. PMID: 21150555


  75. Shlipak MG, Li Y, Fox C, Coresh J, Grunfeld C, Whooley M. Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease. Volume 12. 2011. PMID: 21235779


  76. Taylor SA, Lee GA, Pao VY, Anthonypillai J, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers. Volume 55 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2010. PMID: 20595906


  77. Tien PC, Choi AI, Zolopa AR, Benson C, Tracy R, Scherzer R, Bacchetti P, Shlipak M, Grunfeld C. Inflammation and mortality in HIV-infected adults: analysis of the FRAM study cohort. Volume 55 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2010. PMID: 20581689


  78. Feingold KR, Grunfeld C. The role of HDL in innate immunity. Volume 52 of Issue 1. Journal of lipid research 2010. PMID: 20944062


  79. Delaney JA, Scherzer R, Biggs ML, Shliplak MG, Polak JF, Currier JS, Kronmal RA, Wanke C, Bacchetti P, O'leary D, Tien PC, Grunfeld C. Associations of antiretroviral drug use and HIV-specific risk factors with carotid intima-media thickness. Volume 24 of Issue 14. AIDS (London, England) 2010. PMID: 20671544


  80. Lu B, Jiang YJ, Kim P, Moser A, Elias PM, Grunfeld C, Feingold KR. Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis. Volume 51 of Issue 11. Journal of lipid research 2010. PMID: 20719759


  81. Choi A, Scherzer R, Bacchetti P, Tien PC, Saag MS, Gibert CL, Szczech LA, Grunfeld C, Shlipak MG. Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons. Volume 56 of Issue 5. American journal of kidney diseases : the official journal of the National Kidney Foundation 2010. PMID: 20709438


  82. Grunfeld C. Dyslipidemia and its Treatment in HIV Infection. Volume 18 of Issue 3. 2010. PMID: 20921577


  83. Grunfeld C, Saag M, Cofrancesco J, Lewis CE, Kronmal R, Heymsfield S, Tien PC, Bacchetti P, Shlipak M, Scherzer R. Regional adipose tissue measured by MRI over 5 years in HIV-infected and control participants indicates persistence of HIV-associated lipoatrophy. Volume 24 of Issue 11. AIDS (London, England) 2010. PMID: 20502316


  84. Rao MN, Mulligan K, Tai V, Wen MJ, Dyachenko A, Weinberg M, Li X, Lang T, Grunfeld C, Schwarz JM, Schambelan M. Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance. Volume 95 of Issue 9. 2010. PMID: 20610601


  85. Scherzer R, Shen W, Heymsfield SB, Lewis CE, Kotler DP, Punyanitya M, Bacchetti P, Shlipak MG, Grunfeld C. Intermuscular adipose tissue and metabolic associations in HIV infection. Volume 19 of Issue 2. 2010. PMID: 20539305


  86. Delaney JA, Scherzer R, Polak J, Biggs ML, Kronmal R, Chen H, Sidney S, Grunfeld C. Effect of inter-reader variability on outcomes in studies using carotid intima media thickness quantified by carotid ultrasonography. Volume 25 of Issue 6. European journal of epidemiology 2010. PMID: 20309612


  87. Shrestha S, Irvin MR, Taylor KD, Wiener HW, Pajewski NM, Haritunians T, Delaney JA, Schambelan M, Polak JF, Arnett DK, Chen YD, Grunfeld C. A genome-wide association study of carotid atherosclerosis in HIV-infected men. Volume 24 of Issue 4. AIDS (London, England) 2010. PMID: 20009918


  88. Choi AI, Li Y, Deeks SG, Grunfeld C, Volberding PA, Shlipak MG. Association between kidney function and albuminuria with cardiovascular events in HIV-infected persons. Volume 121 of Issue 5. Circulation 2010. PMID: 20100969


  89. Feingold KR, Shigenaga JK, Patzek SM, Chui LG, Moser A, Grunfeld C. Endotoxin, zymosan, and cytokines decrease the expression of the transcription factor, carbohydrate response element binding protein, and its target genes. Volume 17 of Issue 2. 2010. PMID: 20100709


  90. Grunfeld C, Scherzer R, Varosy PD, Ambarish G, Nasir K, Budoff M. Relation of coronary artery plaque location to extent of coronary artery disease studied by computed tomographic angiography. Volume 4 of Issue 1. 2010. PMID: 20159623


  91. Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers. Volume 24 of Issue 2. AIDS (London, England) 2010. PMID: 19890203


  92. Feingold KR, Grunfeld C. The acute phase response inhibits reverse cholesterol transport. Volume 51 of Issue 4. Journal of lipid research 2010. PMID: 20071695


  93. Cockerham L, Scherzer R, Zolopa A, Rimland D, Lewis CE, Bacchetti P, Grunfeld C, Shlipak M, Tien PC. Association of HIV infection, demographic and cardiovascular risk factors with all-cause mortality in the recent HAART era. Volume 53 of Issue 1. Journal of acquired immune deficiency syndromes (1999) 2010. PMID: 19738484


  94. Lu B, Moser A, Shigenaga JK, Grunfeld C, Feingold KR. The acute phase response stimulates the expression of angiopoietin like protein 4. Volume 391 of Issue 4. Biochemical and biophysical research communications 2009. PMID: 20043872


  95. Lee GA, Schwarz JM, Patzek S, Kim S, Dyachenko A, Wen M, Mulligan K, Schambelan M, Grunfeld C. The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men. Volume 52 of Issue 2. Journal of acquired immune deficiency syndromes (1999) 2009. PMID: 19680131


  96. Grunfeld C, Delaney JA, Wanke C, Currier JS, Scherzer R, Biggs ML, Tien PC, Shlipak MG, Sidney S, Polak JF, O'Leary D, Bacchetti P, Kronmal RA. Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study. Volume 23 of Issue 14. AIDS (London, England) 2009. PMID: 19455012


  97. Feingold KR, Kazemi MR, Magra AL, McDonald CM, Chui LG, Shigenaga JK, Patzek SM, Chan ZW, Londos C, Grunfeld C. ADRP/ADFP and Mal1 expression are increased in macrophages treated with TLR agonists. Volume 209 of Issue 1. 2009. PMID: 19748622


  98. Graf J, Scherzer R, Grunfeld C, Imboden J. Levels of C-reactive protein associated with high and very high cardiovascular risk are prevalent in patients with rheumatoid arthritis. Volume 4 of Issue 7. PloS one 2009. PMID: 19606218


  99. Shlay JC, Sharma S, Peng G, Gibert CL, Grunfeld C. The effect of individual antiretroviral drugs on body composition in HIV-infected persons initiating highly active antiretroviral therapy. Volume 51 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2009. PMID: 19412117


  100. Longenecker CT, Scherzer R, Bacchetti P, Lewis CE, Grunfeld C, Shlipak MG. HIV viremia and changes in kidney function. Volume 23 of Issue 9. AIDS (London, England) 2009. PMID: 19352136


  101. Feingold KR, Moser A, Patzek SM, Shigenaga JK, Grunfeld C. Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm. Volume 50 of Issue 10. Journal of lipid research 2009. PMID: 19443862


  102. Jiang YJ, Uchida Y, Lu B, Kim P, Mao C, Akiyama M, Elias PM, Holleran WM, Grunfeld C, Feingold KR. Ceramide stimulates ABCA12 expression via peroxisome proliferator-activated receptor {delta} in human keratinocytes. Volume 284 of Issue 28. The Journal of biological chemistry 2009. PMID: 19429679


  103. Mulligan K, Khatami H, Schwarz JM, Sakkas GK, DePaoli AM, Tai VW, Wen MJ, Lee GA, Grunfeld C, Schambelan M. The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia. Volume 94 of Issue 4. 2009. PMID: 19174500


  104. Gibert CL, Shlay JC, Sharma S, Bartsch G, Peng G, Grunfeld C. Racial differences in changes of metabolic parameters and body composition in antiretroviral therapy-naive persons initiating antiretroviral therapy. Volume 50 of Issue 1. Journal of acquired immune deficiency syndromes (1999) 2009. PMID: 19295334


  105. Grunfeld C, Feingold KR. Endotoxin in the gut and chylomicrons: translocation or transportation? Volume 50 of Issue 1. Journal of lipid research 2008. PMID: 18957696


  106. Lu B, Lu Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. LPS and proinflammatory cytokines decrease lipin-1 in mouse adipose tissue and 3T3-L1 adipocytes. Volume 295 of Issue 6. 2008. PMID: 18940942


  107. Scherzer R, Shen W, Bacchetti P, Kotler D, Lewis CE, Shlipak MG, Punyanitya M, Heymsfield SB, Grunfeld C. Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjects. Volume 88 of Issue 4. 2008. PMID: 18842798


  108. Grunfeld C. Understanding the complications of antiretroviral drugs. Volume 47 of Issue 4. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008. PMID: 18611156


  109. Feingold KR, Moser AH, Shigenaga JK, Patzek SM, Grunfeld C. Inflammation stimulates the expression of PCSK9. Volume 374 of Issue 2. Biochemical and biophysical research communications 2008. PMID: 18638454


  110. Feingold KR, Wang Y, Moser A, Shigenaga JK, Grunfeld C. LPS decreases fatty acid oxidation and nuclear hormone receptors in the kidney. Volume 49 of Issue 10. Journal of lipid research 2008. PMID: 18574256


  111. Grunfeld C, Kotler DP, Arnett DK, Falutz JM, Haffner SM, Hruz P, Masur H, Meigs JB, Mulligan K, Reiss P, Samaras K. Contribution of metabolic and anthropometric abnormalities to cardiovascular disease risk factors. Volume 118 of Issue 2. Circulation 2008. PMID: 18566314


  112. Grinspoon SK, Grunfeld C, Kotler DP, Currier JS, Lundgren JD, Dubé MP, Lipshultz SE, Hsue PY, Squires K, Schambelan M, Wilson PW, Yarasheski KE, Hadigan CM, Stein JH, Eckel RH. State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary. Volume 118 of Issue 2. Circulation 2008. PMID: 18566320


  113. Reingold J, Wanke C, Kotler D, Lewis C, Tracy R, Heymsfield S, Tien P, Bacchetti P, Scherzer R, Grunfeld C, Shlipak M. Association of HIV infection and HIV/HCV coinfection with C-reactive protein levels: the fat redistribution and metabolic change in HIV infection (FRAM) study. Volume 48 of Issue 2. Journal of acquired immune deficiency syndromes (1999) 2008. PMID: 18344877


  114. Grunfeld C. Insulin resistance in HIV infection: drugs, host responses, or restoration to health? Volume 16 of Issue 2. 2008. PMID: 18591716


  115. Scherzer R, Shen W, Bacchetti P, Kotler D, Lewis CE, Shlipak MG, Heymsfield SB, Grunfeld C. Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected and control subjects. Volume 87 of Issue 6. 2008. PMID: 18541572


  116. Grunfeld C, Feingold KR. HDL and innate immunity: a tale of two apolipoproteins. Volume 49 of Issue 8. Journal of lipid research 2008. PMID: 18515886


  117. Shlay JC, Sharma S, Peng G, Gibert CL, Grunfeld C. Long-term subcutaneous tissue changes among antiretroviral-naive persons initiating stavudine, zidovudine, or abacavir with lamivudine. Volume 48 of Issue 1. Journal of acquired immune deficiency syndromes (1999) 2008. PMID: 18491421


  118. Wohl D, Scherzer R, Heymsfield S, Simberkoff M, Sidney S, Bacchetti P, Grunfeld C. The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men. Volume 48 of Issue 1. Journal of acquired immune deficiency syndromes (1999) 2008. PMID: 18360291


  119. Madden E, Lee G, Kotler DP, Wanke C, Lewis CE, Tracy R, Heymsfield S, Shlipak MG, Bacchetti P, Scherzer R, Grunfeld C. Association of antiretroviral therapy with fibrinogen levels in HIV-infection. Volume 22 of Issue 6. AIDS (London, England) 2008. PMID: 18356600


  120. Pao V, Lee GA, Grunfeld C. HIV therapy, metabolic syndrome, and cardiovascular risk. Volume 10 of Issue 1. 2008. PMID: 18366987


  121. Cofrancesco J, Scherzer R, Tien PC, Gibert CL, Southwell H, Sidney S, Dobs A, Grunfeld C. Illicit drug use and HIV treatment outcomes in a US cohort. Volume 22 of Issue 3. AIDS (London, England) 2008. PMID: 18195562


  122. Feingold KR, Shigenaga JK, Chui LG, Moser A, Khovidhunkit W, Grunfeld C. Infection and inflammation decrease apolipoprotein M expression. Volume 199 of Issue 1. 2007. PMID: 18054359


  123. Odden MC, Scherzer R, Bacchetti P, Szczech LA, Sidney S, Grunfeld C, Shlipak MG. Cystatin C level as a marker of kidney function in human immunodeficiency virus infection: the FRAM study. Volume 167 of Issue 20. Archives of internal medicine 2007. PMID: 17998494


  124. Grunfeld C, Rimland D, Gibert CL, Powderly WG, Sidney S, Shlipak MG, Bacchetti P, Scherzer R, Haffner S, Heymsfield SB. Association of upper trunk and visceral adipose tissue volume with insulin resistance in control and HIV-infected subjects in the FRAM study. Volume 46 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2007. PMID: 18167644


  125. Lee GA, Rao M, Mulligan K, Lo JC, Aweeka F, Schwarz JM, Schambelan M, Grunfeld C. Effects of ritonavir and amprenavir on insulin sensitivity in healthy volunteers. Volume 21 of Issue 16. AIDS (London, England) 2007. PMID: 18090045


  126. Kosmiski LA, Bacchetti P, Kotler DP, Heymsfield SB, Lewis CE, Shlipak MG, Scherzer R, Grunfeld C. Relationship of fat distribution with adipokines in human immunodeficiency virus infection. Volume 93 of Issue 1. 2007. PMID: 17940113


  127. Lee D, Benson CA, Lewis CE, Grunfeld C, Scherzer R. Prevalence and factors associated with dry skin in HIV infection: the FRAM study. Volume 21 of Issue 15. AIDS (London, England) 2007. PMID: 17885295


  128. Grunfeld C, Thompson M, Brown SJ, Richmond G, Lee D, Muurahainen N, Kotler DP. Recombinant human growth hormone to treat HIV-associated adipose redistribution syndrome: 12 week induction and 24-week maintenance therapy. Volume 45 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2007. PMID: 17592343


  129. Lu B, Sims PJ, Wiedmer T, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response. Volume 1771 of Issue 9. Biochimica et biophysica acta 2007. PMID: 17590392


  130. Szczech LA, Grunfeld C, Scherzer R, Canchola JA, van der Horst C, Sidney S, Wohl D, Shlipak MG. Microalbuminuria in HIV infection. Volume 21 of Issue 8. AIDS (London, England) 2007. PMID: 17457094


  131. Shlay JC, Bartsch G, Peng G, Wang J, Grunfeld C, Gibert CL, Visnegarwala F, Raghavan SS, Xiang Y, Farrough M, Perry HE, Kotler D, El-Sadr WM. Long-term body composition and metabolic changes in antiretroviral naive persons randomized to protease inhibitor-, nonnucleoside reverse transcriptase inhibitor-, or protease inhibitor plus nonnucleoside reverse transcriptase inhibitor-based strategy. Volume 44 of Issue 5. Journal of acquired immune deficiency syndromes (1999) 2007. PMID: 17325603


  132. Kim MS, Sweeney TR, Shigenaga JK, Chui LG, Moser A, Grunfeld C, Feingold KR. Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells. Volume 56 of Issue 2. 2007. PMID: 17224343


  133. Kotler DP, Muurahainen N, Grunfeld C, Wanke C, Thompson M, Saag M, Bock D, Simons G, Gertner JM. Effects of growth hormone on visceral adipose tissue and dyslipidemia in HIV, an erratum. Volume 43 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2006. PMID: 17079997


  135. Lee GA, Lo JC, Aweeka F, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers. Volume 43 of Issue 5. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006. PMID: 16886163


  136. Lu B, Moser AH, Shigenaga JK, Feingold KR, Grunfeld C. Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response. Volume 47 of Issue 10. Journal of lipid research 2006. PMID: 16847310


  137. Shen W, Punyanitya M, Chen J, Gallagher D, Albu J, Pi-Sunyer X, Lewis CE, Grunfeld C, Heshka S, Heymsfield SB. Waist circumference correlates with metabolic syndrome indicators better than percentage fat. Volume 14 of Issue 4. 2006. PMID: 16741276


  138. Lu B, Xu FY, Jiang YJ, Choy PC, Hatch GM, Grunfeld C, Feingold KR. Cloning and characterization of a cDNA encoding human cardiolipin synthase (hCLS1). Volume 47 of Issue 6. Journal of lipid research 2006. PMID: 16547353


  139. Tien PC, Benson C, Zolopa AR, Sidney S, Osmond D, Grunfeld C. The study of fat redistribution and metabolic change in HIV infection (FRAM): methods, design, and sample characteristics. Volume 163 of Issue 9. American journal of epidemiology 2006. PMID: 16524955


  140. Grunfeld C, Kotler DP, Dobs A, Glesby M, Bhasin S. Oxandrolone in the treatment of HIV-associated weight loss in men: a randomized, double-blind, placebo-controlled study. Volume 41 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2006. PMID: 16540931


  141. Sweeney TR, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Decreased nuclear hormone receptor expression in the livers of mice in late pregnancy. Volume 290 of Issue 6. 2006. PMID: 16434558


  142. Grunfeld C. Fish oil for treatment of hypertriglyceridemia in HIV infection: fish or foul? Volume 41 of Issue 10. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005. PMID: 16231264


  143. Bacchetti P, Gripshover B, Grunfeld C, Heymsfield S, McCreath H, Osmond D, Saag M, Scherzer R, Shlipak M, Tien P. Fat distribution in men with HIV infection. Volume 40 of Issue 2. Journal of acquired immune deficiency syndromes (1999) 2005. PMID: 16186728


  144. Visnegarwala F, Raghavan SS, Mullin CM, Bartsch G, Wang J, Kotler D, Gibert CL, Shlay J, Grunfeld C, Carr A, El-Sadr W. Sex differences in the associations of HIV disease characteristics and body composition in antiretroviral-naive persons. Volume 82 of Issue 4. 2005. PMID: 16210716


  145. Wang Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines. Volume 46 of Issue 11. Journal of lipid research 2005. PMID: 16106051


  146. Kim MS, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Suppression of estrogen-related receptor alpha and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response. Volume 46 of Issue 10. Journal of lipid research 2005. PMID: 16061943


  147. Kazemi MR, McDonald CM, Shigenaga JK, Grunfeld C, Feingold KR. Adipocyte fatty acid-binding protein expression and lipid accumulation are increased during activation of murine macrophages by toll-like receptor agonists. Volume 25 of Issue 6. 2005. PMID: 15705927


  148. Shlay JC, Visnegarwala F, Bartsch G, Wang J, Peng G, El-Sadr WM, Gibert C, Kotler D, Grunfeld C, Raghavan S. Body composition and metabolic changes in antiretroviral-naive patients randomized to didanosine and stavudine vs. abacavir and lamivudine. Volume 38 of Issue 2. Journal of acquired immune deficiency syndromes (1999) 2005. PMID: 15671799


  149. Lee GA, Rao MN, Grunfeld C. The effects of HIV protease inhibitors on carbohydrate and lipid metabolism. Volume 2 of Issue 1. Current HIV/AIDS reports 2005. PMID: 16091248


  150. Khovidhunkit W, Hachem JP, Medzihradszky KF, Duchateau PN, Shigenaga JK, Moser AH, Movsesyan I, Naya-Vigne J, Kane JP, Feingold KR, Grunfeld C. Parotid secretory protein is an HDL-associated protein with anticandidal activity. Volume 288 of Issue 5. 2005. PMID: 15637169


  151. Lee GA, Rao MN, Grunfeld C. The Effects of HIV Protease Inhibitors on Carbohydrate and Lipid Metabolism. Volume 6 of Issue 6. 2004. PMID: 15538985


  152. Schwarz JM, Lee GA, Park S, Noor MA, Lee J, Wen M, Lo JC, Mulligan K, Schambelan M, Grunfeld C. Indinavir increases glucose production in healthy HIV-negative men. Volume 18 of Issue 13. AIDS (London, England) 2004. PMID: 15316349


  153. Khovidhunkit W, Duchateau PN, Medzihradszky KF, Moser AH, Naya-Vigne J, Shigenaga JK, Kane JP, Grunfeld C, Feingold KR. Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. Volume 176 of Issue 1. 2004. PMID: 15306172


  154. Mafong DD, Lee GA, Yu S, Tien P, Mauro T, Grunfeld C. Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy. Volume 18 of Issue 12. AIDS (London, England) 2004. PMID: 15280791


  155. Lo JC, Mulligan K, Noor MA, Lee GA, Schwarz JM, Grunfeld C, Schambelan M. The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study. Volume 39 of Issue 5. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004. PMID: 15356790


  156. Kim MS, Shigenaga J, Moser A, Grunfeld C, Feingold KR. Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response. Volume 287 of Issue 4. 2004. PMID: 15198932


  157. Lee GA, Mafong DD, Noor MA, Lo JC, Mulligan K, Schwarz JM, Schambelan M, Grunfeld C. HIV protease inhibitors increase adiponectin levels in HIV-negative men. Volume 36 of Issue 1. Journal of acquired immune deficiency syndromes (1999) 2004. PMID: 15097312


  158. Khovidhunkit W, Kim MS, Memon RA, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. Volume 45 of Issue 7. Journal of lipid research 2004. PMID: 15102878


  159. Lee GA, Seneviratne T, Noor MA, Lo JC, Schwarz JM, Aweeka FT, Mulligan K, Schambelan M, Grunfeld C. The metabolic effects of lopinavir/ritonavir in HIV-negative men. Volume 18 of Issue 4. AIDS (London, England) 2004. PMID: 15090769


  160. Kotler DP, Muurahainen N, Grunfeld C, Wanke C, Thompson M, Saag M, Bock D, Simons G, Gertner JM. Effects of growth hormone on abnormal visceral adipose tissue accumulation and dyslipidemia in HIV-infected patients. Volume 35 of Issue 3. Journal of acquired immune deficiency syndromes (1999) 2004. PMID: 15076238


  161. Feingold K, Kim MS, Shigenaga J, Moser A, Grunfeld C. Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Volume 286 of Issue 2. 2004. PMID: 14701665


  162. Tien PC, Grunfeld C. What is HIV-associated lipodystrophy? Defining fat distribution changes in HIV infection. Volume 17 of Issue 1. 2004. PMID: 15090886


  163. Tien PC, Cole SR, Williams CM, Li R, Justman JE, Cohen MH, Young M, Rubin N, Augenbraun M, Grunfeld C. Incidence of lipoatrophy and lipohypertrophy in the women's interagency HIV study. Volume 34 of Issue 5. Journal of acquired immune deficiency syndromes (1999) 2003. PMID: 14657755


  164. Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR. Volume 44 of Issue 9. Journal of lipid research 2003. PMID: 12777468


  165. Kim MS, Shigenaga J, Moser A, Feingold K, Grunfeld C. Repression of farnesoid X receptor during the acute phase response. Volume 278 of Issue 11. The Journal of biological chemistry 2003. PMID: 12519762


  166. Grunfeld C, Tien P. Difficulties in understanding the metabolic complications of acquired immune deficiency syndrome. Volume 37 Suppl 2. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003. PMID: 12942373


  167. Monto A, Alonzo J, Watson JJ, Grunfeld C, Wright TL. Steatosis in chronic hepatitis C: relative contributions of obesity, diabetes mellitus, and alcohol. Volume 36 of Issue 3. 2002. PMID: 12198667


  168. Nonogaki K, Memon RA, Grunfeld C, Feingold KR, Tecott LH. Altered gene expressions involved in energy expenditure in 5-HT(2C) receptor mutant mice. Volume 295 of Issue 2. Biochemical and biophysical research communications 2002. PMID: 12150939


  169. Grunfeld C. Leptin and the immunosuppression of malnutrition. Volume 87 of Issue 7. 2002. PMID: 12107197


  170. Grunfeld C. HIV protease inhibitors and glucose metabolism. Volume 16 of Issue 6. AIDS (London, England) 2002. PMID: 11919495


  171. Noor MA, Seneviratne T, Aweeka FT, Lo JC, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study. AIDS (London, England) 2002. PMID: 11964551


  172. Tien PC, Grunfeld C. The fatty liver in AIDS. Volume 13 of Issue 1. 2002. PMID: 11944634


  173. Faggioni R, Feingold KR, Grunfeld C. Leptin regulation of the immune response and the immunodeficiency of malnutrition. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001. PMID: 11726531


  174. Khovidhunkit W, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Cholesterol efflux by acute-phase high density lipoprotein: role of lecithin: cholesterol acyltransferase. Journal of lipid research 2001. PMID: 11369805


  175. Memon RA, Holleran WM, Uchida Y, Moser AH, Grunfeld C, Feingold KR. Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin. Journal of lipid research 2001. PMID: 11254758


  177. Memon RA, Staprans I, Noor M, Holleran WM, Uchida Y, Moser AH, Feingold KR, Grunfeld C. Infection and inflammation induce LDL oxidation in vivo. Arteriosclerosis, thrombosis, and vascular biology 2000. PMID: 10845869


  178. Khovidhunkit W, Memon RA, Feingold KR, Grunfeld C. Infection and inflammation-induced proatherogenic changes of lipoproteins. The Journal of infectious diseases 2000. PMID: 10839741


  179. Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. The acute phase response is associated with retinoid X receptor repression in rodent liver. The Journal of biological chemistry 2000. PMID: 10747970


  180. Faggioni R, Moser A, Feingold KR, Grunfeld C. Reduced leptin levels in starvation increase susceptibility to endotoxic shock. The American journal of pathology 2000. PMID: 10793089


  181. Staprans I, Pan XM, Rapp JH, Grunfeld C, Feingold KR. Oxidized cholesterol in the diet accelerates the development of atherosclerosis in LDL receptor- and apolipoprotein E-deficient mice. Arteriosclerosis, thrombosis, and vascular biology 2000. PMID: 10712395


  182. Faggioni R, Jones-Carson J, Reed DA, Dinarello CA, Feingold KR, Grunfeld C, Fantuzzi G. Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18. Proceedings of the National Academy of Sciences of the United States of America 2000. PMID: 10681432


  183. Memon RA, Hotamisligil GS, Wiesbrock SM, Uysal KT, Faggioni R, Moser AH, Feingold KR, Grunfeld C. Upregulation of uncoupling protein 2 mRNA in genetic obesity: lack of an essential role for leptin, hyperphagia, increased tissue lipid content, and TNF-alpha. Biochimica et biophysica acta 2000. PMID: 10685029


  184. Mulligan K, Grunfeld C, Tai VW, Algren H, Pang M, Chernoff DN, Lo JC, Schambelan M. Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection. Journal of acquired immune deficiency syndromes (1999) 2000. PMID: 10708054


  185. Khovidhunkit W, Memon RA, Shigenaga JK, Pang M, Schambelan M, Mulligan K, Feingold KR, Grunfeld C. Plasma platelet-activating factor acetylhydrolase activity in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. Metabolism: clinical and experimental 1999. PMID: 10599983


  186. Memon RA, Bass NM, Moser AH, Fuller J, Appel R, Grunfeld C, Feingold KR. Down-regulation of liver and heart specific fatty acid binding proteins by endotoxin and cytokines in vivo. Biochimica et biophysica acta 1999. PMID: 10477831


  187. Memon RA, Holleran WM, Uchida Y, Moser AH, Ichikawa S, Hirabayashi Y, Grunfeld C, Feingold KR. Regulation of glycosphingolipid metabolism in liver during the acute phase response. The Journal of biological chemistry 1999. PMID: 10391911


  188. Memon RA, Fuller J, Moser AH, Feingold KR, Grunfeld C. In vivo regulation of plasma platelet-activating factor acetylhydrolase during the acute phase response. The American journal of physiology 1999. PMID: 10409262


  189. Wood LC, Ashby MN, Grunfeld C, Feingold KR. Cloning of murine translation initiation factor 6 and functional analysis of the homologous sequence YPR016c in Saccharomyces cerevisiae. The Journal of biological chemistry 1999. PMID: 10206977


  190. Feingold KR, Memon RA, Moser AH, Shigenaga JK, Grunfeld C. Endotoxin and interleukin-1 decrease hepatic lipase mRNA levels. Atherosclerosis 1999. PMID: 10030389


  191. Grunfeld C, Marshall M, Shigenaga JK, Moser AH, Tobias P, Feingold KR. Lipoproteins inhibit macrophage activation by lipoteichoic acid. Journal of lipid research 1999. PMID: 9925653


  192. Faggioni R, Fantuzzi G, Gabay C, Moser A, Dinarello CA, Feingold KR, Grunfeld C. Leptin deficiency enhances sensitivity to endotoxin-induced lethality. The American journal of physiology 1999. PMID: 9887187


  193. Memon RA, Fuller J, Moser AH, Smith PJ, Grunfeld C, Feingold KR. Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice. Diabetes 1999. PMID: 9892232


  194. Harris IR, Farrell AM, Memon RA, Grunfeld C, Elias PM, Feingold KR. Expression and regulation of mRNA for putative fatty acid transport related proteins and fatty acyl CoA synthase in murine epidermis and cultured human keratinocytes. The Journal of investigative dermatology 1998. PMID: 9804328


  195. Memon RA, Holleran WM, Moser AH, Seki T, Uchida Y, Fuller J, Shigenaga JK, Grunfeld C, Feingold KR. Endotoxin and cytokines increase hepatic sphingolipid biosynthesis and produce lipoproteins enriched in ceramides and sphingomyelin. Arteriosclerosis, thrombosis, and vascular biology 1998. PMID: 9714132


  196. Feingold KR, Memon RA, Moser AH, Grunfeld C. Paraoxonase activity in the serum and hepatic mRNA levels decrease during the acute phase response. Atherosclerosis 1998. PMID: 9712337


  197. Memon RA, Fuller J, Moser AH, Smith PJ, Feingold KR, Grunfeld C. In vivo regulation of acyl-CoA synthetase mRNA and activity by endotoxin and cytokines. The American journal of physiology 1998. PMID: 9688875


  198. Navasa M, Gordon DA, Hariharan N, Jamil H, Shigenaga JK, Moser A, Fiers W, Pollock A, Grunfeld C, Feingold KR. Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines. Journal of lipid research 1998. PMID: 9643353


  199. Faggioni R, Shigenaga J, Moser A, Feingold KR, Grunfeld C. Induction of UCP2 gene expression by LPS: a potential mechanism for increased thermogenesis during infection. Biochemical and biophysical research communications 1998. PMID: 9514886


  201. Memon RA, Feingold KR, Moser AH, Fuller J, Grunfeld C. Regulation of fatty acid transport protein and fatty acid translocase mRNA levels by endotoxin and cytokines. The American journal of physiology 1998. PMID: 9486149


  202. Feingold KR, Hardardóttir I, Grunfeld C. Beneficial effects of cytokine induced hyperlipidemia. Zeitschrift fur Ernahrungswissenschaft 1998. PMID: 9558731


  203. Faggioni R, Fantuzzi G, Fuller J, Dinarello CA, Feingold KR, Grunfeld C. IL-1 beta mediates leptin induction during inflammation. The American journal of physiology 1998. PMID: 9458919


  204. Feingold KR, Grunfeld C. Lipoproteins: are they important components of host defense? Hepatology (Baltimore, Md.) 1997. PMID: 9398019


  205. Harris IR, Farrell AM, Grunfeld C, Holleran WM, Elias PM, Feingold KR. Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis. The Journal of investigative dermatology 1997. PMID: 9406821


  206. Grunfeld C, Doerrler W, Pang M, Jensen P, Weisgraber KH, Feingold KR. Abnormalities of apolipoprotein E in the acquired immunodeficiency syndrome. The Journal of clinical endocrinology and metabolism 1997. PMID: 9360533


  207. Memon RA, Shechter I, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Endotoxin, tumor necrosis factor, and interleukin-1 decrease hepatic squalene synthase activity, protein, and mRNA levels in Syrian hamsters. Journal of lipid research 1997. PMID: 9300784


  208. Wood LC, Stalder AK, Liou A, Campbell IL, Grunfeld C, Elias PM, Feingold KR. Barrier disruption increases gene expression of cytokines and the 55 kD TNF receptor in murine skin. Experimental dermatology 1997. PMID: 9209892


  209. Schambelan M, Mulligan K, Grunfeld C, Daar ES, LaMarca A, Kotler DP, Wang J, Bozzette SA, Breitmeyer JB. Recombinant human growth hormone in patients with HIV-associated wasting. A randomized, placebo-controlled trial. Serostim Study Group. Annals of internal medicine 1996. PMID: 8967667


  210. Grunfeld C, Pang M, Shigenaga JK, Jensen P, Lallone R, Friedman J, Feingold KR. Serum leptin levels in the acquired immunodeficiency syndrome. The Journal of clinical endocrinology and metabolism 1996. PMID: 8954039


  212. Nonogaki K, Pan XM, Moser AH, Shigenaga J, Staprans I, Sakamoto N, Grunfeld C, Feingold KR. LIF and CNTF, which share the gp130 transduction system, stimulate hepatic lipid metabolism in rats. The American journal of physiology 1996. PMID: 8843746


  213. Yoshida M, Roth RI, Grunfeld C, Feingold KR, Levin J. Soluble (1-->3)-beta-D-glucan purified from Candida albicans: biologic effects and distribution in blood and organs in rabbits. The Journal of laboratory and clinical medicine 1996. PMID: 8759942


  214. Grunfeld C, Zhao C, Fuller J, Pollack A, Moser A, Friedman J, Feingold KR. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. The Journal of clinical investigation 1996. PMID: 8621806


  215. Papadakis MA, Grady D, Black D, Tierney MJ, Gooding GA, Schambelan M, Grunfeld C. Growth hormone replacement in healthy older men improves body composition but not functional ability. Annals of internal medicine 1996. PMID: 8633830


  216. Wood LC, Elias PM, Calhoun C, Tsai JC, Grunfeld C, Feingold KR. Barrier disruption stimulates interleukin-1 alpha expression and release from a pre-formed pool in murine epidermis. The Journal of investigative dermatology 1996. PMID: 8648167


  217. Nonogaki K, Moser AH, Shigenaga J, Feingold KR, Grunfeld C. Beta-nerve growth factor as a mediator of the acute phase response in vivo. Biochemical and biophysical research communications 1996. PMID: 8645286


  218. Feingold KR, Spady DK, Pollock AS, Moser AH, Grunfeld C. Endotoxin, TNF, and IL-1 decrease cholesterol 7 alpha-hydroxylase mRNA levels and activity. Journal of lipid research 1996. PMID: 9026521


  219. Grunfeld C, Feingold KR. Regulation of lipid metabolism by cytokines during host defense. Nutrition (Burbank, Los Angeles County, Calif.) 1996. PMID: 8850215


  220. Papadakis MA, Grady D, Tierney MJ, Black D, Wells L, Grunfeld C. Insulin-like growth factor 1 and functional status in healthy older men. Journal of the American Geriatrics Society 1995. PMID: 7490385


  221. Hardardóttir I, Grunfeld C, Feingold KR. Effects of endotoxin on lipid metabolism. Biochemical Society transactions 1995. PMID: 8654672


  222. Nonogaki K, Pan XM, Moser AH, Staprans I, Feingold KR, Grunfeld C. Keratinocyte growth factor increases fatty acid mobilization and hepatic triglyceride secretion in rats. Endocrinology 1995. PMID: 7664645


  223. Nonogaki K, Moser AH, Pan XM, Staprans I, Grunfeld C, Feingold KR. Lipoteichoic acid stimulates lipolysis and hepatic triglyceride secretion in rats in vivo. Journal of lipid research 1995. PMID: 8558086


  224. Funk JL, Lausier J, Moser AH, Shigenaga JK, Huling S, Nissenson RA, Strewler GJ, Grunfeld C, Feingold KR. Endotoxin induces parathyroid hormone-related protein gene expression in splenic stromal and smooth muscle cells, not in splenic lymphocytes. Endocrinology 1995. PMID: 7628377


  225. Feingold KR, Pollock AS, Moser AH, Shigenaga JK, Grunfeld C. Discordant regulation of proteins of cholesterol metabolism during the acute phase response. Journal of lipid research 1995. PMID: 7595071


  226. Read TE, Grunfeld C, Kumwenda ZL, Calhoun MC, Kane JP, Feingold KR, Rapp JH. Triglyceride-rich lipoproteins prevent septic death in rats. The Journal of experimental medicine 1995. PMID: 7790821


  227. Ly H, Francone OL, Fielding CJ, Shigenaga JK, Moser AH, Grunfeld C, Feingold KR. Endotoxin and TNF lead to reduced plasma LCAT activity and decreased hepatic LCAT mRNA levels in Syrian hamsters. Journal of lipid research 1995. PMID: 7666003


  228. Grunfeld C. State of the art in wasting: an interview with Carl Grunfeld, PhD. Interview by Jeff Getty. BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation 1995. PMID: 11362544


  229. Nonogaki K, Fuller GM, Fuentes NL, Moser AH, Staprans I, Grunfeld C, Feingold KR. Interleukin-6 stimulates hepatic triglyceride secretion in rats. Endocrinology 1995. PMID: 7720663


  230. Feingold KR, Funk JL, Moser AH, Shigenaga JK, Rapp JH, Grunfeld C. Role for circulating lipoproteins in protection from endotoxin toxicity. Infection and immunity 1995. PMID: 7729918


  231. Ottey KA, Wood LC, Grunfeld C, Elias PM, Feingold KR. Cutaneous permeability barrier disruption increases fatty acid synthetic enzyme activity in the epidermis of hairless mice. The Journal of investigative dermatology 1995. PMID: 7861009


  232. Read TE, Grunfeld C, Kumwenda Z, Calhoun MC, Kane JP, Feingold KR, Rapp JH. Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats. Surgery 1995. PMID: 7809838


  233. Nonogaki K, Moser AH, Feingold KR, Grunfeld C. Alpha-adrenergic receptors mediate the hypertriglyceridemia induced by endotoxin, but not tumor necrosis factor, in rats. Endocrinology 1994. PMID: 7988454


  234. Wood LC, Elias PM, Sequeira-Martin SM, Grunfeld C, Feingold KR. Occlusion lowers cytokine mRNA levels in essential fatty acid-deficient and normal mouse epidermis, but not after acute barrier disruption. The Journal of investigative dermatology 1994. PMID: 7798624


  235. Feingold KR, Marshall M, Gulli R, Moser AH, Grunfeld C. Effect of endotoxin and cytokines on lipoprotein lipase activity in mice. Arteriosclerosis and thrombosis : a journal of vascular biology 1994. PMID: 7947614


  236. Doerrler W, Feingold KR, Grunfeld C. Cytokines induce catabolic effects in cultured adipocytes by multiple mechanisms. Cytokine 1994. PMID: 7827285


  237. Funk JL, Shigenaga JK, Moser AH, Krul EJ, Strewler GJ, Feingold KR, Grunfeld C. Cytokine regulation of parathyroid hormone-related protein messenger ribonucleic acid levels in mouse spleen: paradoxical effects of interferon-gamma and interleukin-4. Endocrinology 1994. PMID: 7516868


  238. Marshall MK, Doerrler W, Feingold KR, Grunfeld C. Leukemia inhibitory factor induces changes in lipid metabolism in cultured adipocytes. Endocrinology 1994. PMID: 8013346


  239. Wood LC, Feingold KR, Sequeira-Martin SM, Elias PM, Grunfeld C. Barrier function coordinately regulates epidermal IL-1 and IL-1 receptor antagonist mRNA levels. Experimental dermatology 1994. PMID: 7921651


  240. Feingold KR, Wilson DE, Wood LC, Kwong LK, Moser AH, Grunfeld C. Diabetes increases hepatic hydroxymethyl glutaryl coenzyme A reductase protein and mRNA levels in the small intestine. Metabolism: clinical and experimental 1994. PMID: 8159102


  241. Memon RA, Grunfeld C, Moser AH, Feingold KR. Fatty acid synthesis in obese insulin resistant diabetic mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 1994. PMID: 8200619


  242. Tsai JC, Feingold KR, Crumrine D, Wood LC, Grunfeld C, Elias PM. Permeability barrier disruption alters the localization and expression of TNF alpha/protein in the epidermis. Archives of dermatological research 1994. PMID: 8060154


  243. Feingold KR, Hardardottir I, Memon R, Krul EJ, Moser AH, Taylor JM, Grunfeld C. Effect of endotoxin on cholesterol biosynthesis and distribution in serum lipoproteins in Syrian hamsters. Journal of lipid research 1993. PMID: 8301233


  244. Read TE, Harris HW, Grunfeld C, Feingold KR, Kane JP, Rapp JH. The protective effect of serum lipoproteins against bacterial lipopolysaccharide. European heart journal 1993. PMID: 8131781


  245. Funk JL, Krul EJ, Moser AH, Shigenaga JK, Strewler GJ, Grunfeld C, Feingold KR. Endotoxin increases parathyroid hormone-related protein mRNA levels in mouse spleen. Mediation by tumor necrosis factor. The Journal of clinical investigation 1993. PMID: 8227368


  246. Mulligan K, Grunfeld C, Hellerstein MK, Neese RA, Schambelan M. Anabolic effects of recombinant human growth hormone in patients with wasting associated with human immunodeficiency virus infection. The Journal of clinical endocrinology and metabolism 1993. PMID: 8408471


  247. Grunfeld C, Pang M, Doerrler W, Jensen P, Shimizu L, Feingold KR, Cavalieri RR. Indices of thyroid function and weight loss in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. Metabolism: clinical and experimental 1993. PMID: 8412739


  248. Read TE, Harris HW, Grunfeld C, Feingold KR, Calhoun MC, Kane JP, Rapp JH. Chylomicrons enhance endotoxin excretion in bile. Infection and immunity 1993. PMID: 8335381


  249. Feingold KR, Krauss RM, Pang M, Doerrler W, Jensen P, Grunfeld C. The hypertriglyceridemia of acquired immunodeficiency syndrome is associated with an increased prevalence of low density lipoprotein subclass pattern B. The Journal of clinical endocrinology and metabolism 1993. PMID: 8501146


  250. Memon RA, Grunfeld C, Moser AH, Feingold KR. Tumor necrosis factor mediates the effects of endotoxin on cholesterol and triglyceride metabolism in mice. Endocrinology 1993. PMID: 8477669


  251. Harris HW, Grunfeld C, Feingold KR, Read TE, Kane JP, Jones AL, Eichbaum EB, Bland GF, Rapp JH. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. The Journal of clinical investigation 1993. PMID: 8450032


  252. Funk JL, Feingold KR, Moser AH, Grunfeld C. Lipopolysaccharide stimulation of RAW 264.7 macrophages induces lipid accumulation and foam cell formation. Atherosclerosis 1993. PMID: 8457252


  253. Feingold KR, Staprans I, Memon RA, Moser AH, Shigenaga JK, Doerrler W, Dinarello CA, Grunfeld C. Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance. Journal of lipid research 1992. PMID: 1479286


  254. Feingold KR, Grunfeld C, Pang M, Doerrler W, Krauss RM. LDL subclass phenotypes and triglyceride metabolism in non-insulin-dependent diabetes. Arteriosclerosis and thrombosis : a journal of vascular biology 1992. PMID: 1450181


  255. Memon RA, Feingold KR, Moser AH, Doerrler W, Grunfeld C. In vivo effects of interferon-alpha and interferon-gamma on lipolysis and ketogenesis. Endocrinology 1992. PMID: 1396316


  256. Feingold KR, Grunfeld C. Role of cytokines in inducing hyperlipidemia. Diabetes 1992. PMID: 1526345


  257. Sechi LA, Griffin CA, Grady EF, Grunfeld C, Kalinyak JE, Schambelan M. Tissue-specific regulation of insulin receptor mRNA levels in rats with STZ-induced diabetes mellitus. Diabetes 1992. PMID: 1386819


  258. Wood LC, Jackson SM, Elias PM, Grunfeld C, Feingold KR. Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. The Journal of clinical investigation 1992. PMID: 1644919


  259. Memon RA, Feingold KR, Moser AH, Doerrler W, Adi S, Dinarello CA, Grunfeld C. Differential effects of interleukin-1 and tumor necrosis factor on ketogenesis. The American journal of physiology 1992. PMID: 1514611


  260. Grunfeld C, Feingold KR. Metabolic disturbances and wasting in the acquired immunodeficiency syndrome. The New England journal of medicine 1992. PMID: 1620172


  261. Grunfeld C, Feingold KR. Tumor necrosis factor, interleukin, and interferon induced changes in lipid metabolism as part of host defense. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992. PMID: 1374564


  262. Grunfeld C, Pang M, Doerrler W, Shigenaga JK, Jensen P, Feingold KR. Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. The Journal of clinical endocrinology and metabolism 1992. PMID: 1373735


  263. Adi S, Pollock AS, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Role for monokines in the metabolic effects of endotoxin. Interferon-gamma restores responsiveness of C3H/HeJ mice in vivo. The Journal of clinical investigation 1992. PMID: 1569198


  264. Grunfeld C, Kotler DP. Wasting in the acquired immunodeficiency syndrome. Seminars in liver disease 1992. PMID: 1636120


  266. Grunfeld C, Pang M, Shimizu L, Shigenaga JK, Jensen P, Feingold KR. Resting energy expenditure, caloric intake, and short-term weight change in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. The American journal of clinical nutrition 1992. PMID: 1734684


  267. Grunfeld C. Diabetic foot ulcers: etiology, treatment, and prevention. Advances in internal medicine 1992. PMID: 1557993


  268. Grunfeld C, Kotler DP. Pathophysiology of the AIDS wasting syndrome. AIDS clinical review 1992. PMID: 1606057


  269. Grunfeld C, Memon RA, Rapp JH, Feingold KR. Regulation of hepatic lipid metabolism by cytokines that induce the acute phase response. Folia histochemica et cytobiologica 1992. PMID: 1303901


  271. Grunfeld C, Feingold KR. Tumor necrosis factor, cytokines, and the hyperlipidemia of infection. Trends in endocrinology and metabolism: TEM 1991. PMID: 18411185


  272. Grunfeld C, Dinarello CA, Feingold KR. Tumor necrosis factor-alpha, interleukin-1, and interferon alpha stimulate triglyceride synthesis in HepG2 cells. Metabolism: clinical and experimental 1991. PMID: 1654497


  273. Grunfeld C, Soued M, Adi S, Moser AH, Fiers W, Dinarello CA, Feingold KR. Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha. Cancer research 1991. PMID: 2032220


  274. Feingold KR, Soued M, Adi S, Staprans I, Neese R, Shigenaga J, Doerrler W, Moser A, Dinarello CA, Grunfeld C. Effect of interleukin-1 on lipid metabolism in the rat. Similarities to and differences from tumor necrosis factor. Arteriosclerosis and thrombosis : a journal of vascular biology 1991. PMID: 2029492


  275. Feingold KR, Barker ME, Jones AL, Grunfeld C. Localization of tumor necrosis factor-stimulated DNA synthesis in the liver. Hepatology (Baltimore, Md.) 1991. PMID: 2010173


  276. Williams ML, Coleman RA, Placezk D, Grunfeld C. Neutral lipid storage disease: a possible functional defect in phospholipid- linked triacylglycerol metabolism. Biochimica et biophysica acta 1991. PMID: 2001430


  277. Grunfeld C, Kotler DP, Shigenaga JK, Doerrler W, Tierney A, Wang J, Pierson RN, Feingold KR. Circulating interferon-alpha levels and hypertriglyceridemia in the acquired immunodeficiency syndrome. The American journal of medicine 1991. PMID: 1996584


  278. Grunfeld C, Feingold KR. The metabolic effects of tumor necrosis factor and other cytokines. Biotherapy (Dordrecht, Netherlands) 1991. PMID: 2054255


  279. Feingold KR, Soued M, Adi S, Staprans I, Shigenaga J, Doerrler W, Moser A, Grunfeld C. Tumor necrosis factor-increased hepatic very-low-density lipoprotein production and increased serum triglyceride levels in diabetic rats. Diabetes 1990. PMID: 1978829


  280. Feingold KR, Moser A, Adi S, Soued M, Grunfeld C. Small intestinal fatty acid synthesis is increased in diabetic rats. Endocrinology 1990. PMID: 2226313


  281. Harris HW, Grunfeld C, Feingold KR, Rapp JH. Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice. The Journal of clinical investigation 1990. PMID: 2394827


  282. Feingold KR, Adi S, Staprans I, Moser AH, Neese R, Verdier JA, Doerrler W, Grunfeld C. Diet affects the mechanisms by which TNF stimulates hepatic triglyceride production. The American journal of physiology 1990. PMID: 2382712


  283. Grunfeld C, Adi S, Soued M, Moser A, Fiers W, Feingold KR. Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6. Cancer research 1990. PMID: 2364381


  285. Feingold KR, Soued M, Serio MK, Adi S, Moser AH, Grunfeld C. The effect of diet on tumor necrosis factor stimulation of hepatic lipogenesis. Metabolism: clinical and experimental 1990. PMID: 2352479


  286. Grunfeld C, Palladino MA. Tumor necrosis factor: immunologic, antitumor, metabolic, and cardiovascular activities. Advances in internal medicine 1990. PMID: 2405602


  287. Feingold KR, Soued M, Serio MK, Moser AH, Dinarello CA, Grunfeld C. Multiple cytokines stimulate hepatic lipid synthesis in vivo. Endocrinology 1989. PMID: 2661207


  288. Grunfeld C, Wilking H, Neese R, Gavin LA, Moser AH, Gulli R, Serio MK, Feingold KR. Persistence of the hypertriglyceridemic effect of tumor necrosis factor despite development of tachyphylaxis to its anorectic/cachectic effects in rats. Cancer research 1989. PMID: 2713842


  289. Feingold KR, Serio MK, Adi S, Moser AH, Grunfeld C. Tumor necrosis factor stimulates hepatic lipid synthesis and secretion. Endocrinology 1989. PMID: 2707158


  290. Feingold KR, Soued M, Staprans I, Gavin LA, Donahue ME, Huang BJ, Moser AH, Gulli R, Grunfeld C. Effect of tumor necrosis factor (TNF) on lipid metabolism in the diabetic rat. Evidence that inhibition of adipose tissue lipoprotein lipase activity is not required for TNF-induced hyperlipidemia. The Journal of clinical investigation 1989. PMID: 2703526


  291. Grunfeld C, Gulli R, Moser AH, Gavin LA, Feingold KR. Effect of tumor necrosis factor administration in vivo on lipoprotein lipase activity in various tissues of the rat. Journal of lipid research 1989. PMID: 2754338


  292. Grunfeld C, Kotler DP, Hamadeh R, Tierney A, Wang J, Pierson RN. Hypertriglyceridemia in the acquired immunodeficiency syndrome. The American journal of medicine 1989. PMID: 2910092


  293. Holewski JJ, Moss KM, Stess RM, Graf PM, Grunfeld C. Prevalence of foot pathology and lower extremity complications in a diabetic outpatient clinic. Journal of rehabilitation research and development 1989. PMID: 2666642


  294. Grunfeld C, Sherman BM, Cavalieri RR. The acute effects of human growth hormone administration on thyroid function in normal men. The Journal of clinical endocrinology and metabolism 1988. PMID: 3182961


  295. Grunfeld C, Verdier JA, Neese R, Moser AH, Feingold KR. Mechanisms by which tumor necrosis factor stimulates hepatic fatty acid synthesis in vivo. Journal of lipid research 1988. PMID: 2906959


  296. Feingold KR, Soued M, Grunfeld C. Tumor necrosis factor stimulates DNA synthesis in the liver of intact rats. Biochemical and biophysical research communications 1988. PMID: 3132913


  297. Holewski JJ, Stess RM, Graf PM, Grunfeld C. Aesthesiometry: quantification of cutaneous pressure sensation in diabetic peripheral neuropathy. Journal of rehabilitation research and development 1988. PMID: 3361455


  298. Williams ML, Monger DJ, Rutherford SL, Hincenbergs M, Rehfeld SJ, Grunfeld C. Neutral lipid storage disease with ichthyosis: lipid content and metabolism of fibroblasts. Journal of inherited metabolic disease 1988. PMID: 3139924