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400 Parnassus Avenue, Rm A551 UCSF Box 1222 San Francisco, CA 94117

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Umesh Masharani, MBBS

Professor

Dr. Umesh Masharani is an endocrinologist who cares for patients with diabetes and thyroid disorders. He also has an endocrine faculty practice.

Masharani's research focuses mainly on diabetes, with a particular interest in insulin resistance. He collaborates with colleagues in the family medicine departments to examine the relationships among glucose control, depression and psychosocial stress in people with diabetes. He is part of the islet auto-transplantation group, which has an active program managing patients who require surgical removal of the pancreas for chronic pancreatitis and are candidates for islet auto-transplant, a procedure that allows the patient's body to continue producing insulin. The islet transplant group is also studying donor islet transplants as a treatment for type 1 diabetes.

In addition, Masharani is collaborating with Dr. George Brooks, a professor of integrative biology at the University of California, Berkeley, to examine the impact of exercise and aging on mitochondrial function.

Masharani earned his bachelor's degree in physiological sciences at the University of Oxford. He earned his medical degree at Middlesex Health in London. He completed his residency in internal medicine at University Hospitals Birmingham NHS Foundation Trust in Birmingham, England. He completed a fellowship in endocrinology at UCSF.
Education
Fellowship, - Endocrinology and Metabolism, University of California, San Francisco
Publications
  1. Nesemann JM, Dove D, Brodie FL, Masharani U. Worsening of diabetic retinopathy with initiation of an automated insulin delivery system. American journal of ophthalmology case reports 2026. PMID: 41867356


  2. Ferket BS, Hunink MGM, Masharani U, Max W, Yeboah J, Fleischmann KE. Cost-Effectiveness of Coronary Artery Calcium Scoring for Cardiovascular Disease Prevention in Diabetes: An Analysis From MESA. Journal of the American Heart Association 2025. PMID: 40879032


  3. Wang M, Sushil M, Williams CYK, Miao BY, Kim S, Masharani U, Ku G, Hsiao V, Shah A, Koliwad SK, Butte AJ. Assessment of Large Language Models for Enhancing Diabetologist-Developed Personalized Treatment Plans in Complex Type 2 Diabetes. Clinical diabetes : a publication of the American Diabetes Association 2025. PMID: 41140742


  4. Klepser NS, Weber ES, Li L, Fleischmann KE, Masharani U, Park M, Max WB, Yeboah J, Hunink MGM, Ferket BS. Adherence to GLP-1 receptor agonists and SGLT2 inhibitors by out-of-pocket spending among Medicare beneficiaries with diabetes. Diabetes, obesity & metabolism 2025. PMID: 40667705


  5. Masharani U, Lindsay S, Moon F, Paciorek A, Bergsland E. Metastatic insulinoma-outcomes in the current era. The oncologist 2024. PMID: 39475415


  6. Shah VN, Peters AL, Umpierrez GE, Sherr JL, Akturk HK, Aleppo G, Bally L, Cengiz E, Cinar A, Dungan K, Fabris C, Jacobs PG, Lal RA, Mader JK, Masharani U, Prahalad P, Schmidt S, Zijlstra E, Ho CN, Ayers AT, Tian T, Aaron RE, Klonoff DC. Consensus Report on Glucagon-Like Peptide-1 Receptor Agonists as Adjunctive Treatment for Individuals With Type 1 Diabetes Using an Automated Insulin Delivery System. Journal of diabetes science and technology 2024. PMID: 39517127


  7. Klonoff DC, Freckmann G, Pleus S, Kovatchev BP, Kerr D, Tse CC, Li C, Agus MSD, Dungan K, Voglová Hagerf B, Krouwer JS, Lee WA, Misra S, Rhee SY, Sabharwal A, Seley JJ, Shah VN, Tran NK, Waki K, Worth C, Tian T, Aaron RE, Rutledge K, Ho CN, Ayers AT, Adler A, Ahn DT, Aktürk HK, Al-Sofiani ME, Bailey TS, Baker M, Bally L, Bannuru RR, Bauer EM, Bee YM, Blanchette JE, Cengiz E, Chase JG, Y Chen K, Cherñavvsky D, Clements M, Cote GL, Dhatariya KK, Drincic A, Ejskjaer N, Espinoza J, Fabris C, Fleming GA, Gabbay MAL, Galindo RJ, Gómez-Medina AM, Heinemann L, Hermanns N, Hoang T, Hussain S, Jacobs PG, Jendle J, Joshi SR, Koliwad SK, Lal RA, Leiter LA, Lind M, Mader JK, Maran A, Masharani U, Mathioudakis N, McShane M, Mehta C, Moon SJ, Nichols JH, O'Neal DN, Pasquel FJ, Peters AL, Pfützner A, Pop-Busui R, Ranjitkar P, Rhee CM, Sacks DB, Schmidt S, Schwaighofer SM, Sheng B, Simonson GD, Sode K, Spanakis EK, Spartano NL, Umpierrez GE, Vareth M, Vesper HW, Wang J, Wright E, Wu AHB, Yeshiwas S, Zilbermint M, Kohn MA. The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors. Journal of diabetes science and technology 2024. PMID: 39369312


  8. Osmond AD, Leija RG, Arevalo JA, Curl CC, Duong JJ, Huie MJ, Masharani U, Brooks GA. Aging delays the suppression of lipolysis in the postprandial period. Journal of applied physiology (Bethesda, Md. : 1985) 2024. PMID: 39236144


  9. Arevalo JA, Leija RG, Osmond AD, Curl CC, Duong JJ, Huie MJ, Masharani U, Brooks GA. Delayed and Diminished Postprandial Lactate Shuttling in Healthy Older Men and Women. American journal of physiology. Endocrinology and metabolism 2024. PMID: 39110417


  10. Hessler DM, Fisher L, Guzman S, Strycker L, Polonsky WH, Ahmann A, Aleppo G, Argento NB, Henske J, Kim S, Stephens E, Greenberg K, Masharani U. EMBARK: A Randomized, Controlled Trial Comparing Three Approaches to Reducing Diabetes Distress and Improving HbA1c in Adults With Type 1 Diabetes. Diabetes care 2024. PMID: 38809903


  11. Curl CC, Leija RG, Arevalo JA, Osmond AD, Duong JJ, Huie MJ, Masharani U, Horning MA, Brooks GA. Altered Glucose Kinetics Occurs With Aging, A New Outlook on Metabolic Flexibility. American journal of physiology. Endocrinology and metabolism 2024. PMID: 38895979


  12. Sandy JL, Tittel SR, Rompicherla S, Karges B, James S, Rioles N, Zimmerman AG, Fröhlich-Reiterer E, Maahs DM, Lanzinger S, Craig ME, Ebekozien O, Australasian Diabetes Data Network (ADDN)
    , T1D Exchanged Quality Improvement Collaborative (T1DX-QI)
    , Prospective Diabetes Follow-Up Registry Initiative (DPV). Demographic, Clinical, Management, and Outcome Characteristics of 8,004 Young Children With Type 1 Diabetes. Diabetes care 2024. PMID: 38305782


  13. Frassetto LA, Masharani U. Effects of Alterations in Acid-Base Effects on Insulin Signaling. International journal of molecular sciences 2024. PMID: 38473990


  14. Leija RG, Curl CC, Arevalo JA, Osmond AD, Duong JJ, Huie MJ, Masharani U, Brooks GA. Enteric and systemic postprandial lactate shuttle phases and dietary carbohydrate carbon flow in humans. Nature metabolism 2024. PMID: 38388706


  15. Rodriguez-Valadez JM, Tahsin M, Masharani U, Park M, Hunink MGM, Yeboah J, Li L, Weber E, Berkalieva A, Avezaat L, Max W, Fleischmann KE, Ferket BS. Potential Mediators for Treatment Effects of Novel Diabetes Medications on Cardiovascular and Renal Outcomes: A Meta-Regression Analysis. Journal of the American Heart Association 2024. PMID: 38362889


  16. Tian T, Aaron RE, Yeung AM, Huang J, Drincic A, Seley JJ, Wallia A, Gilbert G, Spanakis EK, Masharani U, Faulds E, Hirsch IB, Dawood GE, Espinoza JC, Mendez CE, Kerr D, Klonoff DC. Use of Continuous Glucose Monitors in the Hospital: The Diabetes Technology Society Hospital Meeting Report 2023. Journal of diabetes science and technology 2023. PMID: 37559371


  17. Niu I, Hsiao EC, Wustrack R, Wysolmerski JJ, Dann P, Masharani U. A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy. Calcified tissue international 2023. PMID: 37358786


  18. Wisel SA, Posselt AM, Szot GL, Nunez M, Santos-Parker K, Gardner JM, Worner G, Roll GR, Syed S, Kelly Y, Ward C, Tavakol M, Johnson K, Masharani U, Stock PG. A Multi-Modal Approach to Islet and Pancreas Transplantation With Calcineurin-Sparing Immunosuppression Maintains Long-Term Insulin Independence in Patients With Type I Diabetes. Transplant international : official journal of the European Society for Organ Transplantation 2023. PMID: 37359825


  19. Rodriguez-Valadez JM, Tahsin M, Fleischmann KE, Masharani U, Yeboah J, Park M, Li L, Weber E, Li Y, Berkalieva A, Max W, Hunink MGM, Ferket BS. Cardiovascular and Renal Benefits of Novel Diabetes Drugs by Baseline Cardiovascular Risk: A Systematic Review, Meta-analysis, and Meta-regression. Diabetes care 2023. PMID: 37220263


  20. Quandt Z, Kim S, Villanueva-Meyer J, Coupe C, Young A, Kang JH, Yazdany J, Schmajuk G, Rush S, Ziv E, Perdigoto AL, Herold K, Lechner MG, Su MA, Tyrrell JB, Bluestone J, Anderson M, Masharani U. Spectrum of Clinical Presentations, Imaging Findings, and HLA Types in Immune Checkpoint Inhibitor-Induced Hypophysitis. Journal of the Endocrine Society 2023. PMID: 36860908


  21. Huang J, Yeung AM, DuBord AY, Wolpert H, Jacobs PG, Lee WA, Drincic A, Spanakis EK, Sherr JL, Prahalad P, Fleming A, Hsiao VC, Kompala T, Lal RA, Fayfman M, Ginsberg BH, Galindo RJ, Stuhr A, Chase JG, Najafi B, Masharani U, Seley JJ, Klonoff DC. Diabetes Technology Meeting 2022. Journal of diabetes science and technology 2023. PMID: 36704821


  22. Huang J, Yeung AM, Nguyen KT, Xu NY, Preiser JC, Rushakoff RJ, Seley JJ, Umpierrez GE, Wallia A, Drincic AT, Gianchandani R, Lansang MC, Masharani U, Mathioudakis N, Pasquel FJ, Schmidt S, Shah VN, Spanakis EK, Stuhr A, Treiber GM, Klonoff DC. Hospital Diabetes Meeting 2022. Journal of diabetes science and technology 2022. PMID: 35904143


  23. Xu NY, Nguyen KT, DuBord AY, Pickup J, Sherr JL, Teymourian H, Cengiz E, Ginsberg BH, Cobelli C, Ahn D, Bellazzi R, Bequette BW, Gandrud Pickett L, Parks L, Spanakis EK, Masharani U, Akturk HK, Melish JS, Kim S, Kang GE, Klonoff DC. Diabetes Technology Meeting 2021. AACE Clinical Case Reports 2022. PMID: 35499170


  24. Masharani U, Strycker LA, Fisher L. The ubiquity of diabetes distress among adults with type 1 diabetes in an urban, academic practice: a template for intervention. AACE Clinical Case Reports 2022. PMID: 35322466


  25. Ferket BS, Hunink MGM, Masharani U, Max W, Yeboah J, Burke GL, Fleischmann KE. Lifetime Cardiovascular Disease Risk by Coronary Artery Calcium Score in Individuals With and Without Diabetes: An Analysis From the Multi-Ethnic Study of Atherosclerosis. AACE Clinical Case Reports 2022. PMID: 35168253


  26. Klonoff DC, Wang J, Rodbard D, Kohn MA, Li C, Liepmann D, Kerr D, Ahn D, Peters AL, Umpierrez GE, Seley JJ, Xu NY, Nguyen KT, Simonson G, Agus MSD, Al-Sofiani ME, Armaiz-Pena G, Bailey TS, Basu A, Battelino T, Bekele SY, Benhamou PY, Bequette BW, Blevins T, Breton MD, Castle JR, Chase JG, Chen KY, Choudhary P, Clements MA, Close KL, Cook CB, Danne T, Doyle FJ, Drincic A, Dungan KM, Edelman SV, Ejskjaer N, Espinoza JC, Fleming GA, Forlenza GP, Freckmann G, Galindo RJ, Gomez AM, Gutow HA, Heinemann L, Hirsch IB, Hoang TD, Hovorka R, Jendle JH, Ji L, Joshi SR, Joubert M, Koliwad SK, Lal RA, Lansang MC, Lee WA, Leelarathna L, Leiter LA, Lind M, Litchman ML, Mader JK, Mahoney KM, Mankovsky B, Masharani U, Mathioudakis NN, Mayorov A, Messler J, Miller JD, Mohan V, Nichols JH, Nørgaard K, O'Neal DN, Pasquel FJ, Philis-Tsimikas A, Pieber T, Phillip M, Polonsky WH, Pop-Busui R, Rayman G, Rhee EJ, Russell SJ, Shah VN, Sherr JL, Sode K, Spanakis EK, Wake DJ, Waki K, Wallia A, Weinberg ME, Wolpert H, Wright EE, Zilbermint M, Kovatchev B. A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings. AACE Clinical Case Reports 2022. PMID: 35348391


  27. Thiruvengadam NR, Forde KA, Miranda J, Kim C, Behr S, Masharani U, Arain MA. Disconnected Pancreatic Duct Syndrome: Pancreatitis of the Disconnected Pancreas and its Role in the Development of Diabetes Mellitus. AACE Clinical Case Reports 2022. PMID: 35060942


  28. Rugo HS, Lacouture ME, Goncalves MD, Masharani U, Aapro MS, O'Shaughnessy JA. A multidisciplinary approach to optimizing care of patients treated with alpelisib. AACE Clinical Case Reports 2021. PMID: 35016012


  29. Masharani U, Strycker LA, Lazar AA, Wu K, Brooks GA. Hyperlactatemia in diabetic ketoacidosis. Diabetic medicine : a journal of the British Diabetic Association 2021. PMID: 34655270


  30. Shang T, Zhang JY, Bequette BW, Raymond JK, Coté G, Sherr JL, Castle J, Pickup J, Pavlovic Y, Espinoza J, Messer LH, Heise T, Mendez CE, Kim S, Ginsberg BH, Masharani U, Galindo RJ, Klonoff DC. Diabetes Technology Meeting 2020. Journal of diabetes science and technology 2021. PMID: 34196228


  31. Ferket BS, Hunink MGM, Masharani U, Max W, Yeboah J, Fleischmann KE. Long-term Predictions of Incident Coronary Artery Calcium to 85 Years of Age for Asymptomatic Individuals With and Without Type 2 Diabetes. Diabetes care 2021. PMID: 34078663


  32. Morey JR, Jiang S, Klein S, Max W, Masharani U, Fleischmann KE, Hunink MGM, Ferket BS. Estimating Long-Term Health Utility Scores and Expenditures for Cardiovascular Disease From the Medical Expenditure Panel Survey. Circulation. Cardiovascular quality and outcomes 2021. PMID: 33761758


  33. Neinstein AB, Masharani U. LETTER TO THE EDITOR from Neinstein et al: Approach to the Patient with Thyrotoxicosis Using Telemedicine. The Journal of clinical endocrinology and metabolism 2020. PMID: 33038240


  34. Kim S, Conrad M, Chuang E, Cai L, Masharani U, Murphy EJ. Calcium Stimulation Test for Insulinoma Localization in an End-stage Renal Disease Patient on Diazoxide. Journal of the Endocrine Society 2020. PMID: 33381673


  35. Kou S, De Cunto C, Baujat G, Wentworth KL, Grogan DR, Brown MA, Di Rocco M, Keen R, Al Mukaddam M, le Quan Sang KH, Masharani U, Kaplan FS, Pignolo RJ, Hsiao EC. Patients with ACVR1R206H mutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of Fibrodysplasia Ossificans Progressiva. Orphanet journal of rare diseases 2020. PMID: 32727600


  36. Shumway M, Fisher L, Hessler D, Bowyer V, Polonsky WH, Masharani U. Economic costs of implementing group interventions to reduce diabetes distress in adults with type 1 diabetes mellitus in the T1-REDEEM trial. Journal of diabetes and its complications 2019. PMID: 31473079


  37. Hessler D, Fisher L, Polonsky W, Strycker L, Parra J, Bowyer V, Dedhia M, Masharani U. There is value in treating elevated levels of diabetes distress: the clinical impact of targeted interventions in adults with Type 1 diabetes. Diabetic medicine : a journal of the British Diabetic Association 2019. PMID: 31314907


  38. Fisher L, Hessler D, Polonsky W, Strycker L, Bowyer V, Masharani U. Toward effective interventions to reduce diabetes distress among adults with type 1 diabetes: Enhancing?Emotion regulation and cognitive skills. Patient education and counseling 2019. PMID: 30952482


  39. Kim S, Dillon WP, Hope TA, El-Sayed IH, van Zante A, Wu K, Masharani U. Ectopic thyroid-stimulating hormone-secreting pituitary adenoma of the nasopharynx diagnosed by 68Ga-DOTA-TATE PET/CT. World neurosurgery 2019. PMID: 30797906


  40. Wentworth KL, Masharani U, Hsiao EC. Therapeutic advances for blocking heterotopic ossification in fibrodysplasia ossificans progressiva. British journal of clinical pharmacology 2018. PMID: 30501012


  41. Masharani U, Alba D. Methadone-Associated Hypoglycemia in Chronic Renal Failure Masquerading as an Insulinoma. Pain medicine (Malden, Mass.) 2018. PMID: 29145621


  42. Fisher L, Hessler D, Polonsky WH, Masharani U, Guzman S, Bowyer V, Strycker L, Ahmann A, Basina M, Blumer I, Chloe C, Kim S, Peters AL, Shumway M, Weihs K, Wu P. T1-REDEEM: A Randomized Controlled Trial to Reduce Diabetes Distress Among Adults With Type 1 Diabetes. Diabetes care 2018. PMID: 29976567


  43. Fisher L, Hessler D, Polonsky W, Strycker L, Guzman S, Bowyer V, Blumer I, Masharani U. Emotion regulation contributes to the development of diabetes distress among adults with type 1 diabetes. Patient education and counseling 2017. PMID: 28739179


  44. Hessler DM, Fisher L, Polonsky WH, Masharani U, Strycker LA, Peters AL, Blumer I, Bowyer V. Diabetes distress is linked with worsening diabetes management over time in adults with Type 1 diabetes. Diabetic medicine : a journal of the British Diabetic Association 2017. PMID: 28498610


  45. Arentson-Lantz EJ, Saeed IH, Frassetto LA, Masharani U, Harnish RJ, Seo Y, VanBrocklin HF, Hawkins RA, Mari-Aparici C, Pampaloni MH, Slater J, Paddon-Jones D, Lang TF. 11C-L-methyl methionine dynamic PET/CT of skeletal muscle: response to protein supplementation compared to L-[ring 13C6] phenylalanine infusion with serial muscle biopsy. Annals of nuclear medicine 2017. PMID: 28260185


  46. Mulvey CK, Van Loon K, Bergsland EK, Masharani U, Nakakura EK. Complicated Case Presentation: Management of Pancreatic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1. Pancreas 2017. PMID: 28187108


  47. Fisher L, Hessler D, Polonsky W, Strycker L, Masharani U, Peters A. Diabetes distress in adults with type 1 diabetes: Prevalence, incidence and change over time. Journal of diabetes and its complications 2016. PMID: 27118163


  48. Bailey K, Yazdi T, Masharani U, Tyrrell B, Butch A, Schaufele F. Advantages and Limitations of Androgen Receptor-Based Methods for Detecting Anabolic Androgenic Steroid Abuse as Performance Enhancing Drugs. PloS one 2016. PMID: 26998755


  49. Fisher L, Hessler DM, Polonsky WH, Masharani U, Peters AL, Blumer I, Strycker LA. Prevalence of depression in Type 1 diabetes and the problem of over-diagnosis. Diabetic medicine : a journal of the British Diabetic Association 2016. PMID: 26433004


  50. Moassesfar S, Masharani U, Frassetto LA, Szot GL, Tavakol M, Stock PG, Posselt AM. A Comparative Analysis of the Safety, Efficacy, and Cost of Islet Versus Pancreas Transplantation in Nonuremic Patients With Type 1 Diabetes. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015. PMID: 26595767


  51. Hindi SM, Wang Y, Jones KD, Nussbaum JC, Chang Y, Masharani U, Bikle D, Shoback DM, Hsiao EC. A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting. Volume 97 of Issue 6. 2015. PMID: 26253396


  52. Masharani U, Sherchan P, Schloetter M, Stratford S, Xiao A, Sebastian A, Nolte Kennedy M, Frassetto L. Metabolic and physiologic effects from consuming a hunter-gatherer (Paleolithic)-type diet in type 2 diabetes. European journal of clinical nutrition 2015. PMID: 25828624


  53. Fisher L, Polonsky WH, Hessler DM, Masharani U, Blumer I, Peters AL, Strycker LA, Bowyer V. Understanding the sources of diabetes distress in adults with type 1 diabetes. Journal of diabetes and its complications 2015. PMID: 25765489


  54. Kapogiannis D, Boxer A, Schwartz JB, Abner EL, Biragyn A, Masharani U, Frassetto L, Petersen RC, Miller BL, Goetzl EJ. Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014. PMID: 25342129


  55. Chandran S, Masharani U, Webber AB, Wojciechowski DM. Prediabetic living kidney donors have preserved kidney function at 10 years after donation. Transplantation 2014. PMID: 24342975


  56. Fisher L, Hessler D, Masharani U, Strycker L. Impact of baseline patient characteristics on interventions to reduce diabetes distress: the role of personal conscientiousness and diabetes self-efficacy. Diabetic medicine : a journal of the British Diabetic Association 2014. PMID: 24494593


  57. Hessler D, Fisher L, Glasgow RE, Strycker LA, Dickinson LM, Arean PA, Masharani U. Reductions in regimen distress are associated with improved management and glycemic control over time. Diabetes care 2013. PMID: 24170750


  58. Draznin B, Gilden J, Golden SH, Inzucchi SE, Baldwin D, Bode BW, Boord JB, Braithwaite SS, Cagliero E, Dungan KM, Falciglia M, Figaro MK, Hirsch IB, Klonoff D, Korytkowski MT, Kosiborod M, Lien LF, Magee MF, Masharani U, Maynard G, McDonnell ME, Moghissi ES, Rasouli N, Rubin DJ, Rushakoff RJ, Sadhu AR, Schwartz S, Seley JJ, Umpierrez GE, Vigersky RA, Low CC, Wexler DJ. Pathways to quality inpatient management of hyperglycemia and diabetes: a call to action. Diabetes care 2013. PMID: 23801791


  59. Fisher L, Hessler D, Glasgow RE, Arean PA, Masharani U, Naranjo D, Strycker LA. REDEEM: a pragmatic trial to reduce diabetes distress. Diabetes care 2013. PMID: 23735726


  60. Masharani U, Gjerde C, McCoy S, Maddux BA, Hessler D, Goldfine ID, Youngren JF. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity. BMC endocrine disorders 2012. PMID: 23194380


  61. Hessler DM, Fisher L, Naranjo D, Masharani U. Young adult African American patients with type 2 diabetes: a high risk patient sub-group with few supports for good diabetes management. Journal of health psychology 2011. PMID: 21963680


  62. Baum T, Yap SP, Karampinos DC, Nardo L, Kuo D, Burghardt AJ, Masharani UB, Schwartz AV, Li X, Link TM. Does vertebral bone marrow fat content correlate with abdominal adipose tissue, lumbar spine bone mineral density, and blood biomarkers in women with type 2 diabetes mellitus? Journal of magnetic resonance imaging : JMRI 2011. PMID: 22190287


  63. Masharani UB, Maddux BA, Li X, Sakkas GK, Mulligan K, Schambelan M, Goldfine ID, Youngren JF. Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle. PloS one 2011. PMID: 21589939


  64. Posselt AM, Szot GL, Frassetto LA, Masharani U, Tavakol M, Amin R, McElroy J, Ramos MD, Kerlan RK, Fong L, Vincenti F, Bluestone JA, Stock PG. Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade. Transplantation 2010. PMID: 20978464


  65. Hessler DM, Fisher L, Mullan JT, Glasgow RE, Masharani U. Patient age: a neglected factor when considering disease management in adults with type 2 diabetes. Patient education and counseling 2010. PMID: 21112720


  66. Burghardt AJ, Issever AS, Schwartz AV, Davis KA, Masharani U, Majumdar S, Link TM. High-resolution peripheral quantitative computed tomographic imaging of cortical and trabecular bone microarchitecture in patients with type 2 diabetes mellitus. The Journal of clinical endocrinology and metabolism 2010. PMID: 20719835


  67. Posselt AM, Bellin MD, Tavakol M, Szot GL, Frassetto LA, Masharani U, Kerlan RK, Fong L, Vincenti FG, Hering BJ, Bluestone JA, Stock PG. Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010. PMID: 20659093


  68. Masharani U, Gjerde C, Evans JL, Youngren JF, Goldfine ID. Effects of controlled-release alpha lipoic acid in lean, nondiabetic patients with polycystic ovary syndrome. Journal of diabetes science and technology 2010. PMID: 20307398


  69. Masharani UB, Becker J. Teplizumab therapy for type 1 diabetes. Expert opinion on biological therapy 2010. PMID: 20095914


  70. Posselt AM, Szot GL, Frassetto LA, Masharani U, Stock PG. Clinical islet transplantation at the University of California, San Francisco. Clinical transplants 2010. PMID: 21698834


  71. Fisher L, Mullan JT, Arean P, Glasgow RE, Hessler D, Masharani U. Diabetes distress but not clinical depression or depressive symptoms is associated with glycemic control in both cross-sectional and longitudinal analyses. Diabetes care 2009. PMID: 19837786


  72. Masharani U, Goldfine ID, Youngren JF. Influence of gender on the relationship between insulin sensitivity, adiposity, and plasma lipids in lean nondiabetic subjects. Metabolism: clinical and experimental 2009. PMID: 19604524


  73. Skaff MM, Mullan JT, Almeida DM, Hoffman L, Masharani U, Mohr D, Fisher L. Daily negative mood affects fasting glucose in type 2 diabetes. Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2009. PMID: 19450031


  74. Masharani U, Rushakoff RJ. Update on systemic management of diabetes. International ophthalmology clinics 2009. PMID: 19349784


  75. Fisher L, Skaff MM, Mullan JT, Arean P, Glasgow R, Masharani U. A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with Type 2 diabetes. Diabetic medicine : a journal of the British Diabetic Association 2008. PMID: 19183314


  76. Sweet MP, Izumisato Y, Way LW, Clark OH, Masharani U, Duh QY. Laparoscopic enucleation of insulinomas. Archives of surgery (Chicago, Ill. : 1960) 2007. PMID: 18086988


  77. Li X, Youngren JF, Hyun B, Sakkas GK, Mulligan K, Majumdar S, Masharani UB, Schambelan M, Goldfine ID. Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T. Magnetic resonance imaging 2007. PMID: 17683890


  78. Fisher L, Skaff MM, Mullan JT, Arean P, Mohr D, Masharani U, Glasgow R, Laurencin G. Clinical depression versus distress among patients with type 2 diabetes: not just a question of semantics. Diabetes care 2007. PMID: 17327318


  79. Archea C, Yen IH, Chen H, Eisner MD, Katz PP, Masharani U, Yelin EH, Earnest G, Blanc PD. Negative life events and quality of life in adults with asthma. Thorax 2006. PMID: 16928721


  80. Herold KC, Gitelman SE, Masharani U, Hagopian W, Bisikirska B, Donaldson D, Rother K, Diamond B, Harlan DM, Bluestone JA. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 2005. PMID: 15919798


  81. Masharani U, Shiboski S, Eisner MD, Katz PP, Janson SL, Granger DA, Blanc PD. Impact of exogenous glucocorticoid use on salivary cortisol measurements among adults with asthma and rhinitis. Psychoneuroendocrinology 2005. PMID: 15919580


  82. Blanc PD, Eisner MD, Katz PP, Yen IH, Archea C, Earnest G, Janson S, Masharani UB, Quinlan PJ, Hammond SK, Thorne PS, Balmes JR, Trupin L, Yelin EH. Impact of the home indoor environment on adult asthma and rhinitis. Journal of occupational and environmental medicine 2005. PMID: 15824627


  83. Steele C, Hagopian WA, Gitelman S, Masharani U, Cavaghan M, Rother KI, Donaldson D, Harlan DM, Bluestone J, Herold KC. Insulin secretion in type 1 diabetes. Diabetes 2004. PMID: 14747294


  84. Campos E, Kotite L, Blanche P, Mitsugi Y, Frost PH, Masharani U, Krauss RM, Havel RJ. Properties of triglyceride-rich and cholesterol-rich lipoproteins in the remnant-like particle fraction of human blood plasma. Journal of lipid research 2002. PMID: 11893772


  85. Roll U, Turck CW, Gitelman SE, Rosenthal SM, Nolte MS, Masharani U, Ziegler AG, Baekkeskov S. Peptide mapping and characterisation of glycation patterns of the glima 38 antigen recognised by autoantibodies in Type I diabetic patients. Diabetologia 2000. PMID: 10855535


  86. Murphy EJ, Davern TJ, Shakil AO, Shick L, Masharani U, Chow H, Freise C, Lee WM, Bass NM. Troglitazone-induced fulminant hepatic failure. Acute Liver Failure Study Group. Digestive diseases and sciences 2000. PMID: 10749332


  87. Masharani U, Schambelan M. The endocrine complications of acquired immunodeficiency syndrome. Advances in internal medicine 1993. PMID: 8438644


  88. Ordovas JM, Civeira F, Genest J, Craig S, Robbins AH, Meade T, Pocovi M, Frossard PM, Masharani U, Wilson PW. Restriction fragment length polymorphisms of the apolipoprotein A-I, C-III, A-IV gene locus. Relationships with lipids, apolipoproteins, and premature coronary artery disease. Atherosclerosis 1991. PMID: 1678604


  89. Masharani U, Wolf D. BglII restriction fragment length polymorphisms at the human p53 gene locus. Human genetics 1990. PMID: 1979960


  90. Genest JJ, Ordovas JM, McNamara JR, Robbins AM, Meade T, Cohn SD, Salem DN, Wilson PW, Masharani U, Frossard PM. DNA polymorphisms of the apolipoprotein B gene in patients with premature coronary artery disease. Atherosclerosis 1990. PMID: 1972879


  91. Masharani U. HinfI RFLP at the human renin (REN) gene locus. Nucleic acids research 1989. PMID: 2563155


  92. Tinklenberg KJ, Masharani U, Coleman RT, Taylor J, Cawthorn R, Frossard P. DraI and ScaI RFLPs at human tyrosine hydroxylase (TH) gene locus. Nucleic acids research 1988. PMID: 2905044


  93. Masharani U, Frossard PM. MspI and HindIII restriction fragment length polymorphisms at the human Na,K-ATPase beta-subunit (ATP1B) gene locus. Human genetics 1988. PMID: 2461341


  94. Masharani U, Nakashima PF, Lim DW, Frossard PM. NsiI and ScaI restriction fragment length polymorphisms at the atrial natriuretic peptides (ANP) gene locus. Human genetics 1988. PMID: 2903848


  95. Masharani U, Coleman RT, Johnson LK, Seilhamer JJ. EcoRI and NsiI RFLPs at a human PLA2 gene on chromosome 1. Nucleic acids research 1988. PMID: 2902574


  96. Masharani U, Wolf D, Frossard PM. BanII and ScaI RFLPs at the human p53 gene locus. Nucleic acids research 1988. PMID: 2901071


  97. Masharani U, Baxter JD, Frossard PM. Two EcoT14I RFLPs at the human renin (REN) gene locus. Nucleic acids research 1988. PMID: 2899876


  98. Masharani U, Frossard PM. MboI RFLP at the human renin (ren) gene locus. Nucleic acids research 1988. PMID: 2895911


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