Mary Malloy, MD

Professor

Websites
Publications

  1. Dong W, Wong KH, Liu Y, Levy-Sakin M, Hung WC, Li M, Li B, Jin SC, Choi J, Lopez-Giraldez F, Vaka D, Poon A, Chu C, Lao R, Balamir M, Movsesyan I, Malloy MJ, Zhao H, Kwok PY, Kane JP, Lifton RP, Pullinger CR. Whole Exome Sequencing Reveals Damaging Gene Variants Associated with Hypoalphalipoproteinemia. AACE Clinical Case Reports 2022. PMID: 35460704


  2. Kane JP, Pullinger CR, Goldfine ID, Malloy MJ. Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus. Current opinion in pharmacology 2021. PMID: 34562838


  4. Pullinger CR, O'Connor PM, Naya-Vigne JM, Kunitake ST, Movsesyan I, Frost PH, Malloy MJ, Kane JP. Levels of Prebeta-1 High-Density Lipoprotein Are a Strong Independent Positive Risk Factor for Coronary Heart Disease and Myocardial Infarction: A Meta-Analysis. Journal of the American Heart Association 2021. PMID: 33728928


  5. Gill PK, Dron JS, Dilliott AA, McIntyre AD, Cao H, Wang J, Movsesyan IG, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. Ancestry-specific profiles of genetic determinants of severe hypertriglyceridemia. Journal of clinical lipidology 2020. PMID: 33303403


  6. Dron JS, Dilliott AA, Lawson A, McIntyre AD, Davis BD, Wang J, Cao H, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia. Arteriosclerosis, thrombosis, and vascular biology 2020. PMID: 32580631


  7. Wong KHY, Levy-Sakin M, Ma W, Gonzaludo N, Mak ACY, Vaka D, Poon A, Chu C, Lao R, Balamir M, Grenville Z, Wong N, Kane JP, Kwok PY, Malloy MJ, Pullinger CR. Three patients with homozygous familial hypercholesterolemia: Genomic sequencing and kindred analysis. Molecular genetics & genomic medicine 2019. PMID: 31617323


  8. Dron JS, Wang J, McIntyre AD, Cao H, Robinson JF, Duell B, Manjoo P, Feng J, Movsesyan I, Malloy MJ, Pullinger CR, Kane J, Hegele RA. Partial LPL deletions: rare copy-number variants contributing towards the polygenic form of severe hypertriglyceridemia. Journal of lipid research 2019. PMID: 31519763


  9. Beleford DT, Diab M, Qubty WF, Malloy MJ, Long RK, Shieh JT. Schimke immunoosseous dysplasia and management considerations for vascular risks. American journal of medical genetics. Part A 2019. PMID: 31039288


  10. Creasy KT, Kane JP, Malloy MJ. Emerging roles of HDL in immune function. Current opinion in lipidology 2018. PMID: 30382953


  11. Dron JS, Wang J, Cao H, McIntyre AD, Iacocca MA, Menard JR, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. Severe hypertriglyceridemia is primarily polygenic. Journal of clinical lipidology 2018. PMID: 30466821


  12. Duell PB, Salen G, Eichler FS, DeBarber AE, Connor SL, Casaday L, Jayadev S, Kisanuki Y, Lekprasert P, Malloy MJ, Ramdhani RA, Ziajka PE, Quinn JF, Su KG, Geller AS, Diffenderfer MR, Schaefer EJ. Diagnosis, treatment, and clinical outcomes in 43 cases with cerebrotendinous xanthomatosis. Journal of clinical lipidology 2018. PMID: 30017468


  13. Wang C, Najm R, Xu Q, Jeong DE, Walker D, Balestra ME, Yoon SY, Yuan H, Li G, Miller ZA, Miller BL, Malloy MJ, Huang Y. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nature medicine 2018. PMID: 29632371


  14. Kane J, Schaefer E, Malloy M. Xenosterolemia: emerging molecular and clinical insights. Volume 28 of Issue 6. 2017. PMID: 29095365


  15. Stock EO, Ferrara CT, O'Connor PM, Naya-Vigne JM, Frost PH, Malloy MJ, Kane JP, Pullinger CR. Levels of prebeta-1 high-density lipoprotein are elevated in 3 phenotypes of dyslipidemia. Volume 12 of Issue 1. 2017. PMID: 29198898


  16. Alhariri A, Hamilton K, Oza V, Cordoro K, Sobreira NL, Malloy M, Slavotinek A. Clinical report: A patient with a late diagnosis of cerebrotendinous xanthomatosis and a response to treatment. Volume 173 of Issue 8. 2017. PMID: 28590052


  17. Quinn AG, Schwemberger R, Stock EO, Movsesyan I, Axtell A, Chang S, Ishida BY, Malloy MJ, Kane JP, Pullinger CR. Moderate statin treatment reduces prebeta-1 high-density lipoprotein levels in dyslipidemic patients. 2017. PMID: 28558949


  18. Kane JP, Malloy MJ. Lipoproteins and amyloid vascular disease. Volume 27 of Issue 6. 2016. PMID: 27805977


  19. Kane JP, Malloy MJ. Emerging molecular strategies for management of dyslipidemias. Volume 26 of Issue 6. 2015. PMID: 26780015


  20. Pullinger CR, Stock EO, Movsesyan I, Malloy MJ, Frost PH, Tripuraneni R, Quinn AG, Ishida BY, Schaefer EJ, Asztalos BF, Kane JP. Identification and metabolic profiling of patients with lysosomal acid lipase deficiency. Volume 9 of Issue 5. 2015. PMID: 26350820


  21. Kane JP, Malloy MJ, Pullinger CR. HDL cholesterol efflux capacity and cardiovascular events. Volume 372 of Issue 19. The New England journal of medicine 2015. PMID: 25946301


  22. Malloy M, Miller B, Kane J. Apolipoprotein E and neurocognitive function--in reply. Volume 72 of Issue 4. 2015. PMID: 25867729


  23. Malloy MJ, Kane JP. Congenital absence of apolipoprotein E and neurological function-reply. Volume 71 of Issue 12. 2014. PMID: 25486213


  24. Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, Miller BL, Kane JP, Kwok PY, Malloy MJ. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. Volume 71 of Issue 10. 2014. PMID: 25111166


  25. Kane J, Malloy MJ. Emerging roles of qualitative properties of lipoproteins in atherosclerosis. Volume 25 of Issue 5. 2014. PMID: 25186202


  26. Sharma V, Witkowski A, Witkowska HE, Dykstra A, Simonsen JB, Nelbach L, Beckstead JA, Pullinger CR, Kane JP, Malloy MJ, Watson G, Forte TM, Ryan RO. Aberrant hetero-disulfide bond formation by the hypertriglyceridemia-associated p.Gly185Cys APOA5 variant (rs2075291). Volume 34 of Issue 10. 2014. PMID: 25127531


  27. Rowland CM, Pullinger CR, Luke MM, Shiffman D, Green L, Movsesyan I, Devlin JJ, Malloy MJ, Kane JP, Undas A. Lipoprotein (a), LPA Ile4399Met, and fibrin clot properties. Volume 133 of Issue 5. 2014. PMID: 24502962


  28. Roberts JD, Hsu JC, Aouizerat BE, Pullinger CR, Malloy MJ, Kane JP, Olgin JE, Marcus GM. Impact of a 4q25 genetic variant in atrial flutter and on the risk of atrial fibrillation after cavotricuspid isthmus ablation. Volume 25 of Issue 3. 2013. PMID: 24237655


  29. Pullinger CR, Goldfine ID, Tanyolaç S, Movsesyan I, Faynboym M, Durlach V, Chiefari E, Foti DP, Frost PH, Malloy MJ, Brunetti A, Kane JP. Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population. Volume 12 of Issue 1. 2013. PMID: 24148075


  30. Kane JP, Malloy MJ. Needed: a better understanding of the antiatherogenic properties of HDL. Volume 24 of Issue 5. 2013. PMID: 24005220


  31. Hossain GS, Lynn EG, Maclean KN, Zhou J, Dickhout JG, Lhoták S, Trigatti B, Capone J, Rho J, Tang D, McCulloch CA, Al-Bondokji I, Malloy MJ, Pullinger CR, Kane JP, Li Y, Shiffman D, Austin RC. Deficiency of TDAG51 protects against atherosclerosis by modulating apoptosis, cholesterol efflux, and peroxiredoxin-1 expression. Volume 2 of Issue 3. 2013. PMID: 23686369


  32. Malloy MJ, Kane JP. Hyperlipidemia and cardiovascular disease. Volume 23 of Issue 6. 2012. PMID: 23160407


  33. Kane JP, Malloy MJ. Prebeta-1 HDL and coronary heart disease. Volume 23 of Issue 4. 2012. PMID: 22517613


  34. Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Volume 9 of Issue 6. 2012. PMID: 22300662


  35. Luke MM, Berger K, Rowland CM, Catanese JJ, Tong CH, Ross DA, Garcia V, Kuhlenbaeumer G, Ringelstein EB, Pullinger CR, Malloy MJ, Deedwania P, Ellis SG, Kane JP, Devlin JJ, Lalouschek W, Mannhalter C. Polymorphisms and noncardioembolic stroke in three case-control studies. Volume 33 of Issue 1. 2011. PMID: 22134093


  36. Waugh JL, Celver J, Sharma M, Dufresne RL, Terzi D, Risch SC, Fairbrother WG, Neve RL, Kane JP, Malloy MJ, Pullinger CR, Gu HF, Tsatsanis C, Hamilton SP, Gold SJ, Zachariou V, Kovoor A. Association between regulator of G protein signaling 9-2 and body weight. Volume 6 of Issue 11. PloS one 2011. PMID: 22132185


  37. Guey LT, Pullinger CR, Ishida BY, O'Connor PM, Zellner C, Francone OL, Laramie JM, Naya-Vigne JM, Siradze KA, Deedwania P, Redberg RF, Frost PH, Seymour AB, Kane JP, Malloy MJ. Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease. Volume 108 of Issue 3. The American journal of cardiology 2011. PMID: 21757044


  38. Ruaño G, Windemuth A, Wu AH, Kane JP, Malloy MJ, Pullinger CR, Kocherla M, Bogaard K, Gordon BR, Holford TR, Gupta A, Seip RL, Thompson PD. Mechanisms of statin-induced myalgia assessed by physiogenomic associations. Volume 218 of Issue 2. 2011. PMID: 21868014


  39. Chiefari E, Tanyolaç S, Paonessa F, Pullinger CR, Capula C, Iiritano S, Mazza T, Forlin M, Fusco A, Durlach V, Durlach A, Malloy MJ, Kane JP, Heiner SW, Filocamo M, Foti DP, Goldfine ID, Brunetti A. Functional variants of the HMGA1 gene and type 2 diabetes mellitus. Volume 305 of Issue 9. JAMA 2011. PMID: 21364139


  40. Durlach V, Durlach A, Movesayan I, Socquard E, Zellner C, Clavel C, Nazeyrollas P, Malloy MJ, Pullinger CR, Kane JP, Ducasse A, Aouizerat BE. Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients. Diabetes & metabolism 2010. PMID: 21145773


  41. Shiffman D, Louie JZ, Rowland CM, Malloy MJ, Kane JP, Devlin JJ. Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus. Volume 212 of Issue 1. 2010. PMID: 20605575


  42. Pan J, Shilian P, Ishida B, Wu X, Kane JP, Malloy MJ, Charles MA. Effect of niacin on preß-1 high-density lipoprotein levels in diabetes. Volume 60 of Issue 2. 2010. PMID: 20303127


  43. Tanyolaç S, Bremer AA, Hodoglugil U, Movsesyan I, Pullinger CR, Heiner SW, Malloy MJ, Kane JP, Goldfine ID. Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects. Volume 7 of Issue 6. 2009. PMID: 19656007


  44. Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Volume 18 of Issue 6. 2008. PMID: 19091795


  45. Meyer TE, Shiffman D, Morrison AC, Rowland CM, Louie JZ, Bare LA, Ross DA, Arellano AR, Chasman DI, Ridker PM, Pankow JS, Coresh J, Malloy MJ, Kane JP, Ellis SG, Devlin JJ, Boerwinkle E. GOSR2 Lys67Arg is associated with hypertension in whites. Volume 22 of Issue 2. 2008. PMID: 19057520


  46. Engler MB, Pullinger CR, Malloy MJ, Natanzon Y, Kulkarni MV, Song J, Eng C, Huuskonen J, Rivera C, Poon A, Bensley M, Sehnert A, Zellner C, Kane J, Aouizerat BE. Genetic variation in phospholipid transfer protein modulates lipoprotein profiles in hyperalphalipoproteinemia. Volume 57 of Issue 12. 2008. PMID: 19013296


  47. Plaisier CL, Kyttälä M, Weissglas-Volkov D, Sinsheimer JS, Huertas-Vazquez A, Riba L, Ramírez-Jiménez S, de Bruin TW, Tusié-Luna T, Aouizerat BE, Pullinger CR, Malloy MJ, Kane JP, Cruz-Bautista I, Herrera MF, Aguilar-Salinas C, Kuusisto J, Laakso M, Taskinen MR, van der Kallen CJ, Pajukanta P. Galanin preproprotein is associated with elevated plasma triglycerides. Volume 29 of Issue 1. 2008. PMID: 18988886


  48. Shiffman D, Kane JP, Louie JZ, Arellano AR, Ross DA, Catanese JJ, Malloy MJ, Ellis SG, Devlin JJ. Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. Volume 3 of Issue 8. PloS one 2008. PMID: 18682748


  49. van der Net JB, Versmissen J, Oosterveer DM, Defesche JC, Yazdanpanah M, Aouizerat BE, Steyerberg EW, Malloy MJ, Pullinger CR, Kane JP, Kastelein JJ, Sijbrands EJ. Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and coronary heart disease risk in familial hypercholesterolemia. Volume 203 of Issue 2. 2008. PMID: 18775537


  50. Lee JC, Weissglas-Volkov D, Kyttälä M, Dastani Z, Cantor RM, Sobel EM, Plaisier CL, Engert JC, van Greevenbroek MM, Kane JP, Malloy MJ, Pullinger CR, Huertas-Vazquez A, Aguilar-Salinas CA, Tusie-Luna T, de Bruin TW, Aouizerat BE, van der Kallen CC, Croce CM, Aqeilan RI, Marcil M, Viikari JS, Lehtimäki T, Raitakari OT, Kuusisto J, Laakso M, Taskinen MR, Genest J, Pajukanta P. WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. Volume 83 of Issue 2. 2008. PMID: 18674750


  51. van der Net JB, Oosterveer DM, Versmissen J, Defesche JC, Yazdanpanah M, Aouizerat BE, Steyerberg EW, Malloy MJ, Pullinger CR, Kastelein JJ, Kane JP, Sijbrands EJ. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. Volume 29 of Issue 18. 2008. PMID: 18599554


  52. Pullinger CR, Aouizerat BE, Movsesyan I, Durlach V, Sijbrands EJ, Nakajima K, Poon A, Dallinga-Thie GM, Hattori H, Green LL, Kwok PY, Havel RJ, Frost PH, Malloy MJ, Kane JP. An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients. Volume 49 of Issue 8. Journal of lipid research 2008. PMID: 18441017


  53. Liu Y, Helms C, Liao W, Zaba LC, Duan S, Gardner J, Wise C, Miner A, Malloy MJ, Pullinger CR, Kane JP, Saccone S, Worthington J, Bruce I, Kwok PY, Menter A, Krueger J, Barton A, Saccone NL, Bowcock AM. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS genetics 2008. PMID: 18369459


  54. Tseng ZH, Aouizerat BE, Pawlikowska L, Vittinghoff E, Lin F, Whiteman D, Poon A, Herrington D, Howard TD, Varosy PD, Hulley SB, Malloy M, Kane J, Kwok PY, Olgin JE. Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease. Volume 5 of Issue 6. 2008. PMID: 18534365


  55. Péterfy M, Ben-Zeev O, Mao HZ, Weissglas-Volkov D, Aouizerat BE, Pullinger CR, Frost PH, Kane JP, Malloy MJ, Reue K, Pajukanta P, Doolittle MH. Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Volume 39 of Issue 12. 2007. PMID: 17994020


  56. Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Volume 28 of Issue 1. 2007. PMID: 17975119


  57. Bare LA, Morrison AC, Rowland CM, Shiffman D, Luke MM, Iakoubova OA, Kane JP, Malloy MJ, Ellis SG, Pankow JS, Willerson JT, Devlin JJ, Boerwinkle E. Five common gene variants identify elevated genetic risk for coronary heart disease. Volume 9 of Issue 10. 2007. PMID: 18073581


  58. Luke MM, Kane JP, Liu DM, Rowland CM, Shiffman D, Cassano J, Catanese JJ, Pullinger CR, Leong DU, Arellano AR, Tong CH, Movsesyan I, Naya-Vigne J, Noordhof C, Feric NT, Malloy MJ, Topol EJ, Koschinsky ML, Devlin JJ, Ellis SG. A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease. Volume 27 of Issue 9. 2007. PMID: 17569884


  59. Wung SF, Kulkarni MV, Pullinger CR, Malloy MJ, Kane JP, Aouizerat BE. The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion. Volume 5. 2006. PMID: 16822320


  60. Shiffman D, Rowland CM, Louie JZ, Luke MM, Bare LA, Bolonick JI, Young BA, Catanese JJ, Stiggins CF, Pullinger CR, Topol EJ, Malloy MJ, Kane JP, Ellis SG, Devlin JJ. Gene variants of VAMP8 and HNRPUL1 are associated with early-onset myocardial infarction. Volume 26 of Issue 7. 2006. PMID: 16690874


  61. Aouizerat BE, Engler MB, Natanzon Y, Kulkarni M, Song J, Eng C, Huuskonen J, Rivera C, Poon A, Bensley M, Sehnert A, Zellner C, Malloy M, Kane J, Pullinger CR. Genetic variation of PLTP modulates lipoprotein profiles in hypoalphalipoproteinemia. Volume 47 of Issue 4. Journal of lipid research 2005. PMID: 16388083


  62. Swarbrick MM, Waldenmaier B, Pennacchio LA, Lind DL, Cavazos MM, Geller F, Merriman R, Ustaszewska A, Malloy M, Scherag A, Hsueh WC, Rief W, Mauvais-Jarvis F, Pullinger CR, Kane JP, Dent R, McPherson R, Kwok PY, Hinney A, Hebebrand J, Vaisse C. Lack of support for the association between GAD2 polymorphisms and severe human obesity. Volume 3 of Issue 9. 2005. PMID: 16122350


  63. Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP. Identification of four gene variants associated with myocardial infarction. Volume 77 of Issue 4. 2005. PMID: 16175505


  64. Engler MM, Engler MB, Malloy MJ, Paul SM, Kulkarni KR, Mietus-Snyder ML. Effect of docosahexaenoic acid on lipoprotein subclasses in hyperlipidemic children (the EARLY study). Volume 95 of Issue 7. The American journal of cardiology 2005. PMID: 15781019


  65. Zellner C, Pullinger CR, Aouizerat BE, Frost PH, Kwok PY, Malloy MJ, Kane JP. Variations in human HM74 (GPR109B) and HM74A (GPR109A) niacin receptors. Volume 25 of Issue 1. 2005. PMID: 15580557


  66. Albert TS, Duchateau PN, Deeb SS, Pullinger CR, Cho MH, Heilbron DC, Malloy MJ, Kane JP, Brown BG. Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL. Volume 46 of Issue 3. Journal of lipid research 2004. PMID: 15604524


  67. Engler MM, Engler MB, Malloy M, Chiu E, Besio D, Paul S, Stuehlinger M, Morrow J, Ridker P, Rifai N, Mietus-Snyder M. Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study. International journal of clinical pharmacology and therapeutics 2004. PMID: 15624283


  68. Soep JB, Mietus-Snyder M, Malloy MJ, Witztum JL, von Scheven E. Assessment of atherosclerotic risk factors and endothelial function in children and young adults with pediatric-onset systemic lupus erythematosus. Volume 51 of Issue 3. Arthritis and rheumatism 2004. PMID: 15188333


  69. Engler MB, Engler MM, Chen CY, Malloy MJ, Browne A, Chiu EY, Kwak HK, Milbury P, Paul SM, Blumberg J, Mietus-Snyder ML. Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. Volume 23 of Issue 3. 2004. PMID: 15190043


  70. Engler MM, Engler MB, Malloy MJ, Chiu EY, Schloetter MC, Paul SM, Stuehlinger M, Lin KY, Cooke JP, Morrow JD, Ridker PM, Rifai N, Miller E, Witztum JL, Mietus-Snyder M. Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Volume 108 of Issue 9. Circulation 2003. PMID: 12912807


  71. Pullinger CR, Kane JP, Malloy MJ. Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders. Volume 1 of Issue 1. 2003. PMID: 15030301


  72. Aouizerat BE, Kulkarni M, Heilbron D, Drown D, Raskin S, Pullinger CR, Malloy MJ, Kane JP. Genetic analysis of a polymorphism in the human apoA-V gene: effect on plasma lipids. Volume 44 of Issue 6. Journal of lipid research 2003. PMID: 12671030


  73. Ryan CM, Schoenfeld DA, Malloy M, Schulz JT, Sheridan RL, Tompkins RG. Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors. Volume 23 of Issue 5. 2002. PMID: 12352131


  74. Pullinger CR, Eng C, Salen G, Shefer S, Batta AK, Erickson SK, Verhagen A, Rivera CR, Mulvihill SJ, Malloy MJ, Kane JP. Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. Volume 110 of Issue 1. The Journal of clinical investigation 2002. PMID: 12093894


  75. Malloy MJ, Kane JP. A risk factor for atherosclerosis: triglyceride-rich lipoproteins. Advances in internal medicine 2001. PMID: 11795072


  76. Drmanac S, Heilbron DC, Pullinger CR, Jafari M, Gietzen D, Ukrainczyk T, Cho MH, Frost PH, Siradze K, Drmanac RT, Kane JP, Malloy MJ. Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins. Journal of cardiovascular pharmacology and therapeutics 2001. PMID: 11452336


  77. Frossard PM, Malloy MJ, Lestringant GG, Kane JP. Haplotypes of the human renin gene associated with essential hypertension and stroke. Journal of human hypertension 2001. PMID: 11224002


  79. Duchateau PN, Movsesyan I, Yamashita S, Sakai N, Hirano K, Schoenhaus SA, O'Connor-Kearns PM, Spencer SJ, Jaffe RB, Redberg RF, Ishida BY, Matsuzawa Y, Kane JP, Malloy MJ. Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects. Journal of lipid research 2000. PMID: 10946010


  80. Nishino M, Malloy MJ, Naya-Vigne J, Russell J, Kane JP, Redberg RF. Lack of association of lipoprotein(a) levels with coronary calcium deposits in asymptomatic postmenopausal women. Journal of the American College of Cardiology 2000. PMID: 10676675


  81. Frossard PM, Lestringant GG, Malloy MJ, Kane JP. Human renin gene BglI dimorphism associated with hypertension in two independent populations. Clinical genetics 1999. PMID: 10665661


  82. Frossard PM, Kane JP, Malloy MJ, Bener A. Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects. Hypertension research : official journal of the Japanese Society of Hypertension 1999. PMID: 10580395


  83. Cheng S, Grow MA, Pallaud C, Klitz W, Erlich HA, Visvikis S, Chen JJ, Pullinger CR, Malloy MJ, Siest G, Kane JP. A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome research 1999. PMID: 10523522


  84. Pullinger CR, Gaffney D, Gutierrez MM, Malloy MJ, Schumaker VN, Packard CJ, Kane JP. The apolipoprotein B R3531C mutation. Characteristics of 24 subjects from 9 kindreds. Journal of lipid research 1999. PMID: 9925662


  85. Cheng S, Pallaud C, Grow MA, Scharf SJ, Erlich HA, Klitz W, Pullinger CR, Malloy MJ, Kane JP, Siest G, Visvikis S. A multilocus genotyping assay for cardiovascular disease. Clinical chemistry and laboratory medicine 1998. PMID: 9806460


  87. O'Connor PM, Zysow BR, Schoenhaus SA, Ishida BY, Kunitake ST, Naya-Vigne JM, Duchateau PN, Redberg RF, Spencer SJ, Mark S, Mazur M, Heilbron DC, Jaffe RB, Malloy MJ, Kane JP. Prebeta-1 HDL in plasma of normolipidemic individuals: influences of plasma lipoproteins, age, and gender. Journal of lipid research 1998. PMID: 9548598


  88. Malloy MJ, Kane JP. Aggressive medical therapy for the prevention and treatment of coronary artery disease. Disease-a-month : DM 1998. PMID: 9457050


  89. Sudhir K, Chou TM, Chatterjee K, Smith EP, Williams TC, Kane JP, Malloy MJ, Korach KS, Rubanyi GM. Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. Circulation 1997. PMID: 9396482


  90. Duchateau PN, Pullinger CR, Orellana RE, Kunitake ST, Naya-Vigne J, O'Connor PM, Malloy MJ, Kane JP. Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L. The Journal of biological chemistry 1997. PMID: 9325276


  91. O'Connor PM, Naya-Vigne JM, Duchateau PN, Ishida BY, Mazur M, Schoenhaus SA, Zysow BR, Malloy MJ, Kunitake ST, Kane JP. Measurement of prebeta-1 HDL in human plasma by an ultrafiltration-isotope dilution technique. Analytical biochemistry 1997. PMID: 9299021


  92. Pullinger CR, Malloy MJ, Shahidi AK, Ghassemzadeh M, Duchateau P, Villagomez J, Allaart J, Kane JP. A novel apolipoprotein C-III variant, apoC-III(Gln38-->Lys), associated with moderate hypertriglyceridemia in a large kindred of Mexican origin. Journal of lipid research 1997. PMID: 9323592


  93. Malloy MJ, Kane JP. Aggressive medical therapy for the prevention and treatment of coronary artery disease. Advances in internal medicine 1997. PMID: 9048115


  94. Hausmann D, Johnson JA, Sudhir K, Mullen WL, Friedrich G, Fitzgerald PJ, Chou TM, Ports TA, Kane JP, Malloy MJ, Yock PG. Angiographically silent atherosclerosis detected by intravascular ultrasound in patients with familial hypercholesterolemia and familial combined hyperlipidemia: correlation with high density lipoproteins. Journal of the American College of Cardiology 1996. PMID: 8636537


  95. Malloy MJ, Ravis WR, Pennell AT, Diskin CJ. Effect of cholestyramine resin on single dose valproate pharmacokinetics. International journal of clinical pharmacology and therapeutics 1996. PMID: 8738857


  97. Pullinger CR, Hennessy LK, Chatterton JE, Liu W, Love JA, Mendel CM, Frost PH, Malloy MJ, Schumaker VN, Kane JP. Familial ligand-defective apolipoprotein B. Identification of a new mutation that decreases LDL receptor binding affinity. The Journal of clinical investigation 1995. PMID: 7883971


  98. Sudhir K, Ports TA, Amidon TM, Goldberger JJ, Bhushan V, Kane JP, Yock P, Malloy MJ. Increased prevalence of coronary ectasia in heterozygous familial hypercholesterolemia. Circulation 1995. PMID: 7867176


  99. Chen GC, Liu W, Duchateau P, Allaart J, Hamilton RL, Mendel CM, Lau K, Hardman DA, Frost PH, Malloy MJ. Conformational differences in human apolipoprotein B-100 among subspecies of low density lipoproteins (LDL). Association of altered proteolytic accessibility with decreased receptor binding of LDL subspecies from hypertriglyceridemic subjects. The Journal of biological chemistry 1994. PMID: 7961878


  100. Malloy MJ, Ravis WR, Pennell AT, Hagan DR, Betagari S, Doshi DH. Influence of cholestyramine resin administration on single dose sulindac pharmacokinetics. International journal of clinical pharmacology and therapeutics 1994. PMID: 7921528


  101. Malloy MJ, Kane JP. Medical management of hyperlipidemic states. Advances in internal medicine 1994. PMID: 8140966


  102. Malloy MJ. Effects of exercise on coronary atherosclerotic lesions. Journal of the American College of Cardiology 1993. PMID: 8335817


  104. Pullinger CR, Zysow BR, Hennessy LK, Frost PH, Malloy MJ, Kane JP. Molecular cloning and characteristics of a new apolipoprotein C-II mutant identified in three unrelated individuals with hypercholesterolemia and hypertriglyceridemia. Human molecular genetics 1993. PMID: 8490626


  105. Malloy MJ, Kane JP. Drs malloy and kane respond. The Western journal of medicine 1992. PMID: 18750862


  106. Hardman DA, Pullinger CR, Hamilton RL, Kane JP, Malloy MJ. Molecular and metabolic basis for the metabolic disorder normotriglyceridemic abetalipoproteinemia. The Journal of clinical investigation 1991. PMID: 1939657


  107. Malloy MJ, Frost PH, Kane JP. Niacin--the long and the short of it. The Western journal of medicine 1991. PMID: 1771892


  108. Ameis D, Kobayashi J, Davis RC, Ben-Zeev O, Malloy MJ, Kane JP, Lee G, Wong H, Havel RJ, Schotz MC. Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene. The Journal of clinical investigation 1991. PMID: 2010533


  109. Kane JP, Malloy MJ, Ports TA, Phillips NR, Diehl JC, Havel RJ. Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens. JAMA 1990. PMID: 2243428


  110. Kane JP, Malloy MJ. Treatment of hyperlipidemia. Annual review of medicine 1990. PMID: 2184745


  111. Koo C, Wernette-Hammond ME, Garcia Z, Malloy MJ, Uauy R, East C, Bilheimer DW, Mahley RW, Innerarity TL. Uptake of cholesterol-rich remnant lipoproteins by human monocyte-derived macrophages is mediated by low density lipoprotein receptors. The Journal of clinical investigation 1988. PMID: 3163347


  112. Coleman RT, Cawthon RM, Malloy MJ, Kane JP, Nakashima PF, Frossard PM. Bsm I RFLP at the human apolipoprotein AI-CIII gene complex locus. Nucleic acids research 1988. PMID: 2895918


  113. Coleman RT, Malloy MJ, Kane JP, Frossard PM. NcoI dimorphic site located 8kb 3' to the human apolipoprotein AIV (APOA4) gene. Nucleic acids research 1988. PMID: 2894008


  114. Kane JP, Malloy MJ. When to treat hyperlipidemia. Advances in internal medicine 1988. PMID: 3278503


  115. Malloy MJ, Kane JP, Kunitake ST, Tun P. Complementarity of colestipol, niacin, and lovastatin in treatment of severe familial hypercholesterolemia. Annals of internal medicine 1987. PMID: 3662275


  116. Frossard PM, Coleman RT, Malloy MJ, Kane JP, Levy-Wilson B, Appleby VA. Human apolipoprotein CI (apoC1) gene locus: DraI dimorphic site. Nucleic acids research 1987. PMID: 2881281


  117. Frossard PM, Lim DW, Coleman RT, Funke H, Assmann G, Malloy MJ, Kane JP. Human apolipoprotein CI (ApoC1) gene locus: BglI dimorphic site. Nucleic acids research 1987. PMID: 2881271


  118. Frossard PM, Coleman RT, Dillan NA, Lim DW, Malloy MJ, Kane JP, Funke H, Assmann G. DraI RFLP in the human apolipoprotein AI-CIII-AIV gene complex. Nucleic acids research 1986. PMID: 2878415


  119. Coleman RT, Dillan NA, Lim DW, Malloy MJ, Kane JP, Frossard PM. TaqI and XbaI RFLPs detected with a human apo IV (Apo4) cDNA probe. Nucleic acids research 1986. PMID: 2877436


  120. Stalenhoef AF, Malloy MJ, Kane JP, Havel RJ. Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in patients with familial dysbetalipoproteinemia. The Journal of clinical investigation 1986. PMID: 3745433


  121. Menzel HJ, Kane JP, Malloy MJ, Havel RJ. A variant primary structure of apolipoprotein C-II in individuals of African descent. The Journal of clinical investigation 1986. PMID: 3944271


  122. Stalenhoef AF, Malloy MJ, Kane JP, Havel RJ. Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich lipoproteins in normal and lipoprotein lipase-deficient humans. Proceedings of the National Academy of Sciences of the United States of America 1984. PMID: 6584917


  123. Kane JP, Chen GC, Hamilton RL, Hardman DA, Malloy MJ, Havel RJ. Remnants of lipoproteins of intestinal and hepatic origin in familial dysbetalipoproteinemia. Arteriosclerosis (Dallas, Tex.) 1983. PMID: 6824496


  124. Malloy MJ, Kane JP. Hypolipidemia. The Medical clinics of North America 1982. PMID: 7040848


  125. Kane JP, Malloy MJ. Treatment of hypercholesterolemia. The Medical clinics of North America 1982. PMID: 7040850


  126. Crain LS, Dienst ER, Malloy MJ. The effects of primary care versus traditional training on career choice in pediatrics. The Western journal of medicine 1981. PMID: 7340128


  127. Malloy MJ, Kane JP, Hardman DA, Hamilton RL, Dalal KB. Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein. The Journal of clinical investigation 1981. PMID: 7229035


  128. Kane JP, Malloy MJ, Tun P, Phillips NR, Freedman DD, Williams ML, Rowe JS, Havel RJ. Normalization of low-density-lipoprotein levels in heterozygous familial hypercholesterolemia with a combined drug regimen. The New England journal of medicine 1981. PMID: 7003391


  129. Malloy MJ, Kane JP, Rowe JS. Familial hypercholesterolemia in children: treatment with p-aminosalicylic acid. Pediatrics 1978. PMID: 205828


  130. Kane JP, Malloy MJ. Editorial: Early prevention of atherosclerosis. The Western journal of medicine 1975. PMID: 1154774