Kenneth Feingold, MD

Professor Emeritus

Education
Residency, - School of Medicine, University of California, San Francisco
Websites
Publications

  1. Feingold KR, Chait A. Recent advances in lipidology. Best practice & research. Clinical endocrinology & metabolism 2023. PMID: 36914551


  2. Feingold KR. The bidirectional interaction of COVID-19 infections and lipoproteins. Best practice & research. Clinical endocrinology & metabolism 2023. PMID: 36894344


  3. Feingold KR. Lipid and Lipoprotein Metabolism. Endocrinology and metabolism clinics of North America 2022. PMID: 35963623


  4. Feingold KR, Chait A. Approach to patients with elevated low-density lipoprotein cholesterol levels. AACE Clinical Case Reports 2022. PMID: 35487874


  5. Chait A, Feingold KR. Approach to patients with hypertriglyceridemia. AACE Clinical Case Reports 2022. PMID: 35459627


  6. Feingold KR. The Bidirectional Link Between HDL and COVID 19 Infections. Journal of lipid research 2021. PMID: 33741421


  7. Schmuth M, Feingold KR, Elias PM. Stress test of the skin: The cutaneous permeability barrier treadmill. Experimental dermatology 2019. PMID: 31682042


  8. Feingold KR. Maximizing the benefits of cholesterol-lowering drugs. Current opinion in lipidology 2019. PMID: 31335331


  9. Atri D, Furfaro D, Dhaliwal G, Feingold KR, Manesh R. Going from A to Z. Volume 378 of Issue 1. The New England journal of medicine 2018. PMID: 29298151


  10. Hu L, Mauro TM, Dang E, Man G, Zhang J, Lee D, Wang G, Feingold KR, Elias PM, Man MQ. Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum Inflammatory Cytokines. Volume 137 of Issue 6. 2017. PMID: 28115059


  11. Gupta N, Feingold K, Dhaliwal G. Stressing Signal Versus Noise: An Exercise in Clinical Reasoning. Volume 32 of Issue 1. Journal of general internal medicine 2016. PMID: 27798784


  12. Feingold KR, Grunfeld C. Effect of inflammation on HDL structure and function. Volume 27 of Issue 5. 2016. PMID: 27495134


  13. Brondfield S, Feingold KR. Symptomatic Graves' Disease After Autoimmune Hypothyroidism. Volume 129 of Issue 5. The American journal of medicine 2016. PMID: 26772649


  14. Duprez DA, Otvos J, Tracy RP, Feingold KR, Greenland P, Gross MD, Lima JA, Mackey RH, Neaton JD, Sanchez OA, Jacobs DR. High-Density Lipoprotein Subclasses and Noncardiovascular, Noncancer Chronic Inflammatory-Related Events Versus Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis. Volume 4 of Issue 9. 2015. PMID: 26370448


  16. Feingold KR. Statin myopathy: a problem looking for a solution. Volume 239 of Issue 1. 2015. PMID: 25576849


  17. Sun R, Celli A, Crumrine D, Hupe M, Adame LC, Pennypacker SD, Park K, Uchida Y, Feingold KR, Elias PM, Ilic D, Mauro TM. Lowered humidity produces human epidermal equivalents with enhanced barrier properties. Volume 21 of Issue 1. 2015. PMID: 24803151


  18. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages. Volume 55 of Issue 12. Journal of lipid research 2014. PMID: 25320346


  19. Lin TK, Man MQ, Santiago JL, Scharschmidt TC, Hupe M, Martin-Ezquerra G, Youm JK, Zhai Y, Trullas C, Feingold KR, Elias PM. Paradoxical benefits of psychological stress in inflammatory dermatoses models are glucocorticoid mediated. Volume 134 of Issue 12. 2014. PMID: 24991965


  20. Man MQ, Lin TK, Santiago JL, Celli A, Zhong L, Huang ZM, Roelandt T, Hupe M, Sundberg JP, Silva KA, Crumrine D, Martin-Ezquerra G, Trullas C, Sun R, Wakefield JS, Wei ML, Feingold KR, Mauro TM, Elias PM. Basis for enhanced barrier function of pigmented skin. Volume 134 of Issue 9. 2014. PMID: 24732399


  22. Feingold K, Elias P. The important role of lipids in the epidermis and their role in the formation and maintenance of the cutaneous barrier. Volume 1841 of Issue 3. Biochimica et biophysica acta 2014. PMID: 24564908


  23. Feingold KR. Capsule commentary on Radin, pitfalls in hemoglobin A1c measurement: when results may be misleading. Volume 29 of Issue 2. Journal of general internal medicine 2014. PMID: 24065382


  24. Elias PM, Williams ML, Choi EH, Feingold KR. Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis. Volume 1841 of Issue 3. Biochimica et biophysica acta 2013. PMID: 24291327


  25. Feingold KR, Elias PM. Role of lipids in the formation and maintenance of the cutaneous permeability barrier. Volume 1841 of Issue 3. Biochimica et biophysica acta 2013. PMID: 24262790


  26. Yau RK, Strotmeyer ES, Resnick HE, Sellmeyer DE, Feingold KR, Cauley JA, Vittinghoff E, De Rekeneire N, Harris TB, Nevitt MC, Cummings SR, Shorr RI, Schwartz AV. Diabetes and risk of hospitalized fall injury among older adults. Volume 36 of Issue 12. Diabetes care 2013. PMID: 24130352


  27. Feingold KR. Innate immunity stimulates permeability barrier homeostasis. Volume 133 of Issue 8. 2013. PMID: 23856931


  28. Jiang YJ, Kim P, Uchida Y, Elias PM, Bikle DD, Grunfeld C, Feingold KR. Ceramides stimulate caspase-14 expression in human keratinocytes. Volume 22 of Issue 2. 2013. PMID: 23362869


  29. Feingold KR, Grunfeld C. Lipids: a key player in the battle between the host and microorganisms. Volume 53 of Issue 12. Journal of lipid research 2012. PMID: 23075464


  30. Lin TK, Man MQ, Santiago JL, Park K, Roelandt T, Oda Y, Hupe M, Crumrine D, Lee HJ, Gschwandtner M, Thyssen JP, Trullas C, Tschachler E, Feingold KR, Elias PM. Topical antihistamines display potent anti-inflammatory activity linked in part to enhanced permeability barrier function. Volume 133 of Issue 2. 2012. PMID: 23014339


  31. Celli A, Zhai Y, Jiang YJ, Crumrine D, Elias PM, Feingold KR, Mauro TM. Tight junction properties change during epidermis development. Volume 21 of Issue 10. 2012. PMID: 22882565


  32. Feingold KR. Lamellar bodies: the key to cutaneous barrier function. Volume 132 of Issue 8. 2012. PMID: 22797297


  33. Feingold KR, Shigenaga JK, Kazemi MR, McDonald CM, Patzek SM, Cross AS, Moser A, Grunfeld C. Mechanisms of triglyceride accumulation in activated macrophages. Volume 92 of Issue 4. 2012. PMID: 22753953


  34. Feingold KR, Grunfeld C. Psoriasis: it's more than just the skin. Volume 53 of Issue 8. Journal of lipid research 2012. PMID: 22685321


  35. Elias PM, Williams ML, Feingold KR. Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders. Volume 30 of Issue 3. 2012. PMID: 22507046


  36. Feingold KR, Denda M. Regulation of permeability barrier homeostasis. Volume 30 of Issue 3. 2012. PMID: 22507038


  37. Feingold KR, Shigenaga JK, Cross AS, Moser A, Grunfeld C. Angiopoietin like protein 4 expression is decreased in activated macrophages. Volume 421 of Issue 3. Biochemical and biophysical research communications 2012. PMID: 22538368


  38. Feingold KR, Grunfeld C, Heuer JG, Gupta A, Cramer M, Zhang T, Shigenaga JK, Patzek SM, Chan ZW, Moser A, Bina H, Kharitonenkov A. FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis. Volume 153 of Issue 6. 2012. PMID: 22474187


  39. Man W, Man M, Hupe M, Martin-Ezquerra G, Feingold KR, Elias PM, Man MQ. Topical herbal extract (Huangdang mixture) exhibits both preventive and therapeutic effects in murine acute irritant contact dermatitis. Volume 50 of Issue 11. 2011. PMID: 22004502


  41. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation inhibits GPR81 expression in adipose tissue. Volume 60 of Issue 10. 2011. PMID: 21751047


  42. Hatano Y, Elias PM, Crumrine D, Feingold KR, Katagiri K, Fujiwara S. Efficacy of combined peroxisome proliferator-activated receptor-a ligand and glucocorticoid therapy in a murine model of atopic dermatitis. Volume 131 of Issue 9. 2011. PMID: 21633371


  43. Jiang YJ, Kim P, Lu YF, Feingold KR. PPARgamma activators stimulate aquaporin 3 expression in keratinocytes/epidermis. Volume 20 of Issue 7. 2011. PMID: 21457357


  44. Feingold KR. Lipid metabolism in the epidermis. Volume 3 of Issue 2. 2011. PMID: 21695011


  47. Feingold KR, Moser A, Shigenaga JK, Grunfeld C. Inflammation inhibits the expression of phosphoenolpyruvate carboxykinase in liver and adipose tissue. Volume 18 of Issue 2. 2011. PMID: 21450790


  48. Man M, Hupe M, Mackenzie D, Kim H, Oda Y, Crumrine D, Lee SH, Martin-Ezquerra G, Trullas C, Mauro TM, Feingold KR, Elias PM, Man MQ. A topical Chinese herbal mixture improves epidermal permeability barrier function in normal murine skin. Volume 20 of Issue 3. 2011. PMID: 21323748


  49. Feingold KR, Grunfeld C. The role of HDL in innate immunity. Volume 52 of Issue 1. Journal of lipid research 2010. PMID: 20944062


  50. Lu B, Jiang YJ, Kim P, Moser A, Elias PM, Grunfeld C, Feingold KR. Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis. Volume 51 of Issue 11. Journal of lipid research 2010. PMID: 20719759


  51. Jiang YJ, Lu B, Crumrine D, Elias PM, Feingold KR. IL-6 stimulates but is not essential for stratum corneum formation and permeability barrier development during gestation. Volume 19 of Issue 8. 2010. PMID: 19758319


  52. Jiang YJ, Lu B, Tarling EJ, Kim P, Man MQ, Crumrine D, Edwards PA, Elias PM, Feingold KR. Regulation of ABCG1 expression in human keratinocytes and murine epidermis. Volume 51 of Issue 11. Journal of lipid research 2010. PMID: 20675829


  53. Fluhr JW, Elias PM, Man MQ, Hupe M, Selden C, Sundberg JP, Tschachler E, Eckhart L, Mauro TM, Feingold KR. Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification? Volume 130 of Issue 8. 2010. PMID: 20376063


  54. Feingold KR, Shigenaga JK, Patzek SM, Chui LG, Moser A, Grunfeld C. Endotoxin, zymosan, and cytokines decrease the expression of the transcription factor, carbohydrate response element binding protein, and its target genes. Volume 17 of Issue 2. 2010. PMID: 20100709


  55. Feingold KR, Grunfeld C. The acute phase response inhibits reverse cholesterol transport. Volume 51 of Issue 4. Journal of lipid research 2010. PMID: 20071695


  56. Lu B, Moser A, Shigenaga JK, Grunfeld C, Feingold KR. The acute phase response stimulates the expression of angiopoietin like protein 4. Volume 391 of Issue 4. Biochemical and biophysical research communications 2009. PMID: 20043872


  57. Feingold KR. Does inhibition of apolipoprotein B synthesis produce foie gras? Volume 51 of Issue 5. Journal of lipid research 2009. PMID: 20042543


  58. Hatano Y, Man MQ, Uchida Y, Crumrine D, Mauro TM, Feingold KR, Elias PM, Holleran WM. Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators. Volume 125 of Issue 1. 2009. PMID: 19818482


  59. Hachem JP, Roelandt T, Schürer N, Pu X, Fluhr J, Giddelo C, Man MQ, Crumrine D, Roseeuw D, Feingold KR, Mauro T, Elias PM. Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes. Volume 130 of Issue 2. 2009. PMID: 19741713


  60. Feingold KR, Kazemi MR, Magra AL, McDonald CM, Chui LG, Shigenaga JK, Patzek SM, Chan ZW, Londos C, Grunfeld C. ADRP/ADFP and Mal1 expression are increased in macrophages treated with TLR agonists. Volume 209 of Issue 1. 2009. PMID: 19748622


  61. Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM. Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. Volume 124 of Issue 3. 2009. PMID: 19733297


  62. Jiang YJ, Barish G, Lu B, Evans RM, Crumrine D, Schmuth M, Elias PM, Feingold KR. PPARd activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation. Volume 130 of Issue 2. 2009. PMID: 19675577


  63. Feingold KR, Moser A, Patzek SM, Shigenaga JK, Grunfeld C. Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm. Volume 50 of Issue 10. Journal of lipid research 2009. PMID: 19443862


  64. Jiang YJ, Uchida Y, Lu B, Kim P, Mao C, Akiyama M, Elias PM, Holleran WM, Grunfeld C, Feingold KR. Ceramide stimulates ABCA12 expression via peroxisome proliferator-activated receptor {delta} in human keratinocytes. Volume 284 of Issue 28. The Journal of biological chemistry 2009. PMID: 19429679


  65. Schwartz AV, Garnero P, Hillier TA, Sellmeyer DE, Strotmeyer ES, Feingold KR, Resnick HE, Tylavsky FA, Black DM, Cummings SR, Harris TB, Bauer DC. Pentosidine and increased fracture risk in older adults with type 2 diabetes. Volume 94 of Issue 7. 2009. PMID: 19383780


  66. Man M, Elias PM, Man W, Wu Y, Bourguignon LY, Feingold KR, Man MQ. The role of CD44 in cutaneous inflammation. Volume 18 of Issue 11. 2009. PMID: 19469887


  67. Demerjian M, Choi EH, Man MQ, Chang S, Elias PM, Feingold KR. Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis. Volume 18 of Issue 7. 2009. PMID: 19236478


  68. Jiang YJ, Lu B, Crumrine D, Man MQ, Elias PM, Feingold KR. IL-1alpha accelerates stratum corneum formation and improves permeability barrier homeostasis during murine fetal development. Volume 54 of Issue 2. 2009. PMID: 19216058


  69. Hatano Y, Man MQ, Uchida Y, Crumrine D, Scharschmidt TC, Kim EG, Mauro TM, Feingold KR, Elias PM, Holleran WM. Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis. Volume 129 of Issue 7. 2009. PMID: 19177139


  70. Gunathilake R, Schurer NY, Shoo BA, Celli A, Hachem JP, Crumrine D, Sirimanna G, Feingold KR, Mauro TM, Elias PM. pH-regulated mechanisms account for pigment-type differences in epidermal barrier function. Volume 129 of Issue 7. 2009. PMID: 19177137


  71. Roelandt T, Giddelo C, Heughebaert C, Denecker G, Hupe M, Crumrine D, Kusuma A, Haftek M, Roseeuw D, Declercq W, Feingold KR, Elias PM, Hachem JP. The "caveolae brake hypothesis" and the epidermal barrier. Volume 129 of Issue 4. 2008. PMID: 19005485


  72. Feingold KR. The outer frontier: the importance of lipid metabolism in the skin. Volume 50 Suppl. Journal of lipid research 2008. PMID: 18980941


  73. Grunfeld C, Feingold KR. Endotoxin in the gut and chylomicrons: translocation or transportation? Volume 50 of Issue 1. Journal of lipid research 2008. PMID: 18957696


  74. Lu B, Lu Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. LPS and proinflammatory cytokines decrease lipin-1 in mouse adipose tissue and 3T3-L1 adipocytes. Volume 295 of Issue 6. 2008. PMID: 18940942


  75. Fluhr JW, Man MQ, Hachem JP, Crumrine D, Mauro TM, Elias PM, Feingold KR. Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification. Volume 129 of Issue 2. 2008. PMID: 18704104


  76. Elias PM, Arbiser J, Brown BE, Rossiter H, Man MQ, Cerimele F, Crumrine D, Gunathilake R, Choi EH, Uchida Y, Tschachler E, Feingold KR. Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia: implications for the pathogenesis of psoriasis. Volume 173 of Issue 3. 2008. PMID: 18688025


  77. Feingold KR, Moser AH, Shigenaga JK, Patzek SM, Grunfeld C. Inflammation stimulates the expression of PCSK9. Volume 374 of Issue 2. Biochemical and biophysical research communications 2008. PMID: 18638454


  78. Feingold KR, Wang Y, Moser A, Shigenaga JK, Grunfeld C. LPS decreases fatty acid oxidation and nuclear hormone receptors in the kidney. Volume 49 of Issue 10. Journal of lipid research 2008. PMID: 18574256


  79. Slominski A, Wortsman J, Paus R, Elias PM, Tobin DJ, Feingold KR. Skin as an endocrine organ: implications for its function. Volume 5 of Issue 2. 2008. PMID: 19492070


  80. Grunfeld C, Feingold KR. HDL and innate immunity: a tale of two apolipoproteins. Volume 49 of Issue 8. Journal of lipid research 2008. PMID: 18515886


  81. Man MQ, Shi Y, Man M, Lee SH, Demerjian M, Chang S, Feingold KR, Elias PM. Chinese herbal medicine (Tuhuai extract) exhibits topical anti-proliferative and anti-inflammatory activity in murine disease models. Volume 17 of Issue 8. 2008. PMID: 18341576


  82. Schmuth M, Jiang YJ, Dubrac S, Elias PM, Feingold KR. Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology. Volume 49 of Issue 3. Journal of lipid research 2008. PMID: 18182682


  83. Demerjian M, Hachem JP, Tschachler E, Denecker G, Declercq W, Vandenabeele P, Mauro T, Hupe M, Crumrine D, Roelandt T, Houben E, Elias PM, Feingold KR. Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2. Volume 172 of Issue 1. 2007. PMID: 18156206


  84. Schwartz AV, Vittinghoff E, Sellmeyer DE, Feingold KR, de Rekeneire N, Strotmeyer ES, Shorr RI, Vinik AI, Odden MC, Park SW, Faulkner KA, Harris TB. Diabetes-related complications, glycemic control, and falls in older adults. Volume 31 of Issue 3. Diabetes care 2007. PMID: 18056893


  85. Feingold KR, Shigenaga JK, Chui LG, Moser A, Khovidhunkit W, Grunfeld C. Infection and inflammation decrease apolipoprotein M expression. Volume 199 of Issue 1. 2007. PMID: 18054359


  86. Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, Elias PM. Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. Volume 117 of Issue 11. The Journal of clinical investigation 2007. PMID: 17975669


  87. Aberg KM, Man MQ, Gallo RL, Ganz T, Crumrine D, Brown BE, Choi EH, Kim DK, Schröder JM, Feingold KR, Elias PM. Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. Volume 128 of Issue 4. 2007. PMID: 17943185


  88. Feingold KR. Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis. Volume 48 of Issue 12. Journal of lipid research 2007. PMID: 17872588


  89. Man MQ, Barish GD, Schmuth M, Crumrine D, Barak Y, Chang S, Jiang Y, Evans RM, Elias PM, Feingold KR. Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation. Volume 128 of Issue 2. 2007. PMID: 17713572


  90. Man MQ, Hatano Y, Lee SH, Man M, Chang S, Feingold KR, Leung DY, Holleran W, Uchida Y, Elias PM. Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. Volume 128 of Issue 1. 2007. PMID: 17671515


  91. Jiang YJ, Lu B, Kim P, Paragh G, Schmitz G, Elias PM, Feingold KR. PPAR and LXR activators regulate ABCA12 expression in human keratinocytes. Volume 128 of Issue 1. 2007. PMID: 17611579


  92. Feingold KR, Schmuth M, Elias PM. The regulation of permeability barrier homeostasis. Volume 127 of Issue 7. 2007. PMID: 17568800


  93. Choi EH, Man MQ, Xu P, Xin S, Liu Z, Crumrine DA, Jiang YJ, Fluhr JW, Feingold KR, Elias PM, Mauro TM. Stratum corneum acidification is impaired in moderately aged human and murine skin. Volume 127 of Issue 12. 2007. PMID: 17554364


  94. Ilic D, Mao-Qiang M, Crumrine D, Dolganov G, Larocque N, Xu P, Demerjian M, Brown BE, Lim ST, Ossovskaya V, Schlaepfer DD, Fisher SJ, Feingold KR, Elias PM, Mauro TM. Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization. Volume 170 of Issue 6. 2007. PMID: 17525272


  95. Lu B, Sims PJ, Wiedmer T, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response. Volume 1771 of Issue 9. Biochimica et biophysica acta 2007. PMID: 17590392


  96. Kim MS, Sweeney TR, Shigenaga JK, Chui LG, Moser A, Grunfeld C, Feingold KR. Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells. Volume 56 of Issue 2. 2007. PMID: 17224343


  97. Van Q, Liu J, Lu B, Feingold KR, Shi Y, Lee RM, Hatch GM. Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells. Volume 401 of Issue 1. 2007. PMID: 16939411


  98. Staprans I, Pan XM, Rapp JH, Moser AH, Feingold KR. Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins. Volume 47 of Issue 11. Journal of lipid research 2006. PMID: 16894239


  99. Choi EH, Demerjian M, Crumrine D, Brown BE, Mauro T, Elias PM, Feingold KR. Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function. Volume 291 of Issue 6. 2006. PMID: 16857896


  100. Lu B, Moser AH, Shigenaga JK, Feingold KR, Grunfeld C. Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response. Volume 47 of Issue 10. Journal of lipid research 2006. PMID: 16847310


  101. Jiang YJ, Lu B, Kim P, Elias PM, Feingold KR. Regulation of ABCA1 expression in human keratinocytes and murine epidermis. Volume 47 of Issue 10. Journal of lipid research 2006. PMID: 16825673


  103. Bourguignon LY, Ramez M, Gilad E, Singleton PA, Man MQ, Crumrine DA, Elias PM, Feingold KR. Hyaluronan-CD44 interaction stimulates keratinocyte differentiation, lamellar body formation/secretion, and permeability barrier homeostasis. Volume 126 of Issue 6. 2006. PMID: 16557236


  104. Hachem JP, Houben E, Crumrine D, Man MQ, Schurer N, Roelandt T, Choi EH, Uchida Y, Brown BE, Feingold KR, Elias PM. Serine protease signaling of epidermal permeability barrier homeostasis. Volume 126 of Issue 9. 2006. PMID: 16691196


  105. Wu Q, Ortegon AM, Tsang B, Doege H, Feingold KR, Stahl A. FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity. Volume 26 of Issue 9. 2006. PMID: 16611988


  106. Schwartz AV, Sellmeyer DE, Vittinghoff E, Palermo L, Lecka-Czernik B, Feingold KR, Strotmeyer ES, Resnick HE, Carbone L, Beamer BA, Park SW, Lane NE, Harris TB, Cummings SR. Thiazolidinedione use and bone loss in older diabetic adults. Volume 91 of Issue 9. 2006. PMID: 16608888


  107. Hachem JP, Wagberg F, Schmuth M, Crumrine D, Lissens W, Jayakumar A, Houben E, Mauro TM, Leonardsson G, Brattsand M, Egelrud T, Roseeuw D, Clayman GL, Feingold KR, Williams ML, Elias PM. Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome. Volume 126 of Issue 7. 2006. PMID: 16601670


  108. Lu B, Xu FY, Jiang YJ, Choy PC, Hatch GM, Grunfeld C, Feingold KR. Cloning and characterization of a cDNA encoding human cardiolipin synthase (hCLS1). Volume 47 of Issue 6. Journal of lipid research 2006. PMID: 16547353


  109. Demerjian M, Man MQ, Choi EH, Brown BE, Crumrine D, Chang S, Mauro T, Elias PM, Feingold KR. Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model. Volume 15 of Issue 3. 2006. PMID: 16480422


  110. Man MQ, Choi EH, Schmuth M, Crumrine D, Uchida Y, Elias PM, Holleran WM, Feingold KR. Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing. Volume 126 of Issue 2. 2006. PMID: 16374473


  111. Sweeney TR, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Decreased nuclear hormone receptor expression in the livers of mice in late pregnancy. Volume 290 of Issue 6. 2006. PMID: 16434558


  112. Schmuth M, Ortegon AM, Mao-Qiang M, Elias PM, Feingold KR, Stahl A. Differential expression of fatty acid transport proteins in epidermis and skin appendages. Volume 125 of Issue 6. 2005. PMID: 16354187


  113. Fluhr JW, Crumrine D, Mao-Qiang M, Moskowitz DG, Elias PM, Feingold KR. Topical liver x receptor activators accelerate postnatal acidification of stratum corneum and improve function in the neonate. Volume 125 of Issue 6. 2005. PMID: 16354191


  114. Staprans I, Pan XM, Rapp JH, Feingold KR. The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis. Volume 49 of Issue 11. 2005. PMID: 16270280


  115. Lu B, Jiang YJ, Man MQ, Brown B, Elias PM, Feingold KR. Expression and regulation of 1-acyl-sn-glycerol- 3-phosphate acyltransferases in the epidermis. Volume 46 of Issue 11. Journal of lipid research 2005. PMID: 16150824


  116. Jiang YJ, Kim P, Elias PM, Feingold KR. LXR and PPAR activators stimulate cholesterol sulfotransferase type 2 isoform 1b in human keratinocytes. Volume 46 of Issue 12. Journal of lipid research 2005. PMID: 16150827


  117. Hachem JP, Man MQ, Crumrine D, Uchida Y, Brown BE, Rogiers V, Roseeuw D, Feingold KR, Elias PM. Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity. Volume 125 of Issue 3. 2005. PMID: 16117792


  118. Wang Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines. Volume 46 of Issue 11. Journal of lipid research 2005. PMID: 16106051


  119. Choi EH, Man MQ, Wang F, Zhang X, Brown BE, Feingold KR, Elias PM. Is endogenous glycerol a determinant of stratum corneum hydration in humans? Volume 125 of Issue 2. 2005. PMID: 16098039


  120. Kim MS, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Suppression of estrogen-related receptor alpha and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response. Volume 46 of Issue 10. Journal of lipid research 2005. PMID: 16061943


  121. Choi EH, Brown BE, Crumrine D, Chang S, Man MQ, Elias PM, Feingold KR. Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity. Volume 124 of Issue 3. 2005. PMID: 15737200


  122. Kazemi MR, McDonald CM, Shigenaga JK, Grunfeld C, Feingold KR. Adipocyte fatty acid-binding protein expression and lipid accumulation are increased during activation of murine macrophages by toll-like receptor agonists. Volume 25 of Issue 6. 2005. PMID: 15705927


  123. Khovidhunkit W, Hachem JP, Medzihradszky KF, Duchateau PN, Shigenaga JK, Moser AH, Movsesyan I, Naya-Vigne J, Kane JP, Feingold KR, Grunfeld C. Parotid secretory protein is an HDL-associated protein with anticandidal activity. Volume 288 of Issue 5. 2005. PMID: 15637169


  124. Schwartz AV, Sellmeyer DE, Strotmeyer ES, Tylavsky FA, Feingold KR, Resnick HE, Shorr RI, Nevitt MC, Black DM, Cauley JA, Cummings SR, Harris TB. Diabetes and bone loss at the hip in older black and white adults. Volume 20 of Issue 4. 2004. PMID: 15765178


  125. Khovidhunkit W, Duchateau PN, Medzihradszky KF, Moser AH, Naya-Vigne J, Shigenaga JK, Kane JP, Grunfeld C, Feingold KR. Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. Volume 176 of Issue 1. 2004. PMID: 15306172


  126. Presland RB, Coulombe PA, Eckert RL, Mao-Qiang M, Feingold KR, Elias PM. Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. Volume 123 of Issue 3. 2004. PMID: 15304104


  127. Mao-Qiang M, Fowler AJ, Schmuth M, Lau P, Chang S, Brown BE, Moser AH, Michalik L, Desvergne B, Wahli W, Li M, Metzger D, Chambon PH, Elias PM, Feingold KR. Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation. Volume 123 of Issue 2. 2004. PMID: 15245430


  128. Fluhr JW, Mao-Qiang M, Brown BE, Hachem JP, Moskowitz DG, Demerjian M, Haftek M, Serre G, Crumrine D, Mauro TM, Elias PM, Feingold KR. Functional consequences of a neutral pH in neonatal rat stratum corneum. Volume 123 of Issue 1. 2004. PMID: 15191554


  129. Schmuth M, Elias PM, Hanley K, Lau P, Moser A, Willson TM, Bikle DD, Feingold KR. The effect of LXR activators on AP-1 proteins in keratinocytes. Volume 123 of Issue 1. 2004. PMID: 15191540


  130. Kim MS, Shigenaga J, Moser A, Grunfeld C, Feingold KR. Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response. Volume 287 of Issue 4. 2004. PMID: 15198932


  131. Khovidhunkit W, Kim MS, Memon RA, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. Volume 45 of Issue 7. Journal of lipid research 2004. PMID: 15102878


  132. Schmuth M, Haqq CM, Cairns WJ, Holder JC, Dorsam S, Chang S, Lau P, Fowler AJ, Chuang G, Moser AH, Brown BE, Mao-Qiang M, Uchida Y, Schoonjans K, Auwerx J, Chambon P, Willson TM, Elias PM, Feingold KR. Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. Volume 122 of Issue 4. 2004. PMID: 15102088


  133. Schmuth M, Fluhr JW, Crumrine DC, Uchida Y, Hachem JP, Behne M, Moskowitz DG, Christiano AM, Feingold KR, Elias PM. Structural and functional consequences of loricrin mutations in human loricrin keratoderma (Vohwinkel syndrome with ichthyosis). Volume 122 of Issue 4. 2004. PMID: 15102081


  134. Feingold K, Kim MS, Shigenaga J, Moser A, Grunfeld C. Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Volume 286 of Issue 2. 2004. PMID: 14701665


  135. Elias PM, Crumrine D, Rassner U, Hachem JP, Menon GK, Man W, Choy MH, Leypoldt L, Feingold KR, Williams ML. Basis for abnormal desquamation and permeability barrier dysfunction in RXLI. Volume 122 of Issue 2. 2004. PMID: 15009711


  136. Fluhr JW, Behne MJ, Brown BE, Moskowitz DG, Selden C, Mao-Qiang M, Mauro TM, Elias PM, Feingold KR. Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum. Volume 122 of Issue 2. 2004. PMID: 15009712


  137. Stone SJ, Myers HM, Watkins SM, Brown BE, Feingold KR, Elias PM, Farese RV. Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. Volume 279 of Issue 12. The Journal of biological chemistry 2003. PMID: 14668353


  138. Hachem JP, Crumrine D, Fluhr J, Brown BE, Feingold KR, Elias PM. pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion. Volume 121 of Issue 2. 2003. PMID: 12880427


  139. Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR. Volume 44 of Issue 9. Journal of lipid research 2003. PMID: 12777468


  140. Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RW, Gratton E, Feingold K, Holleran WM, Elias PM, Mauro TM. Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. Volume 120 of Issue 6. 2003. PMID: 12787127


  141. Fluhr JW, Mao-Qiang M, Brown BE, Wertz PW, Crumrine D, Sundberg JP, Feingold KR, Elias PM. Glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice. Volume 120 of Issue 5. 2003. PMID: 12713573


  143. Kao JS, Fluhr JW, Man MQ, Fowler AJ, Hachem JP, Crumrine D, Ahn SK, Brown BE, Elias PM, Feingold KR. Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities. Volume 120 of Issue 3. 2003. PMID: 12603860


  144. Fowler AJ, Sheu MY, Schmuth M, Kao J, Fluhr JW, Rhein L, Collins JL, Willson TM, Mangelsdorf DJ, Elias PM, Feingold KR. Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. Volume 120 of Issue 2. 2003. PMID: 12542530


  145. Staprans I, Pan XM, Rapp JH, Feingold KR. Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum. Volume 44 of Issue 4. Journal of lipid research 2003. PMID: 12562864


  146. Kim MS, Shigenaga J, Moser A, Feingold K, Grunfeld C. Repression of farnesoid X receptor during the acute phase response. Volume 278 of Issue 11. The Journal of biological chemistry 2003. PMID: 12519762


  147. Elias P, Ahn S, Brown B, Crumrine D, Feingold KR. Origin of the epidermal calcium gradient: regulation by barrier status and role of active vs passive mechanisms. Volume 119 of Issue 6. 2002. PMID: 12485427


  148. Schmuth M, Schoonjans K, Yu QC, Fluhr JW, Crumrine D, Hachem JP, Lau P, Auwerx J, Elias PM, Feingold KR. Role of peroxisome proliferator-activated receptor alpha in epidermal development in utero. Volume 119 of Issue 6. 2002. PMID: 12485431


  149. Elias PM, Tsai J, Menon GK, Holleran WM, Feingold KR. The potential of metabolic interventions to enhance transdermal drug delivery. Volume 7 of Issue 1. 2002. PMID: 12518797


  150. Bikle DD, Ng D, Oda Y, Hanley K, Feingold K, Xie Z. The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3. Volume 119 of Issue 5. 2002. PMID: 12445200


  151. Nonogaki K, Memon RA, Grunfeld C, Feingold KR, Tecott LH. Altered gene expressions involved in energy expenditure in 5-HT(2C) receptor mutant mice. Volume 295 of Issue 2. Biochemical and biophysical research communications 2002. PMID: 12150939


  152. Elias PM, Schmuth M, Uchida Y, Rice RH, Behne M, Crumrine D, Feingold KR, Holleran WM, Pharm D. Basis for the permeability barrier abnormality in lamellar ichthyosis. Volume 11 of Issue 3. 2002. PMID: 12102664


  153. Kömüves LG, Schmuth M, Fowler AJ, Elias PM, Hanley K, Man MQ, Moser AH, Lobaccaro JM, Williams ML, Mangelsdorf DJ, Feingold KR. Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. Volume 118 of Issue 1. 2002. PMID: 11851872


  154. Sheu MY, Fowler AJ, Kao J, Schmuth M, Schoonjans K, Auwerx J, Fluhr JW, Man MQ, Elias PM, Feingold KR. Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. Volume 118 of Issue 1. 2002. PMID: 11851881


  155. Tsuruoka H, Khovidhunkit W, Brown BE, Fluhr JW, Elias PM, Feingold KR. Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements. Volume 277 of Issue 4. The Journal of biological chemistry 2001. PMID: 11707442