Edward Hsiao, MD, PhD

Professor

EDUCATION/CLINICAL TRAINING
MD: MD, PhD, Johns Hopkins Medical School, 2001
Residency: Johns Hopkins Hospital, Baltimore, MD, Internal Medicine, 2001-2004
Fellowship: UCSF, Division of Diabetes, Endocrinology and Metabolism, 2004-2007
Board Certifications: Internal Medicine, 2004; Endocrinology and Metabolism, 2006

ACADEMIC INTERESTS
My research is driven by a desire to understand how major hormonal and regulatory pathways determine the specification, differentiation, and morphogenesis of mesenchymal tissues such as bone, cartilage, muscle, and fat. Mis-regulation of these pathways leads to significant medical diseases, including the inappropriate formation of mineralized tissues in atherosclerosis, heterotopic ossification, and cancer.

My research focuses on understanding how these regulatory signals control normal and pathologic tissue formation as a way to identifying new therapeutic avenues for treating human diseases. Our laboratory takes a comprehensive approach to understanding hormone signaling in human diseases using synthetic biology approaches, mouse models, and human stem cell models.

By combining multiple approaches with state-of-the art methods, our laboratory is working to develop a broader understanding of the biology underlying skeletal development, devise novel therapeutic approaches for treating human skeletal disorders and bone injuries, and examine how hormone signals affect important tissues such as fat, muscle, bone, cartilage, and blood vessels.

CLINICAL INTERESTS:
General Endocrinology with an interest in inherited skeletal diseases, including fibrous dysplasia of the bone (FD), McCune-Albright syndrome (MAS), and fibrodysplasia ossificans progressiva (FOP).

Appointments: 415-353-2350
Availability: General Endocrinology, 3rd Tuesday PM of each month

Laboratory website: https://hsiaolab.ucsf.edu
Education
2019 - Diversity, Equity, and Inclusion Champion Training, University of California
M.D., 2001 - School of Medicine, Johns Hopkins University
Publications

  1. Horsley PJ, Bailey DL, Schembri G, Hsiao E, Drummond J, Back MF. The role of amino acid PET in radiotherapy target volume delineation for adult-type diffuse gliomas: A review of the literature. Critical reviews in oncology/hematology 2024. PMID: 39521308


  2. Azad AA, Bressel M, Tan H, Voskoboynik M, Suder A, Weickhardt AJ, Guminski A, Francis RJ, Saghebi J, Dhiantravan N, Joshua AM, Emmett L, Horvath L, Murphy DG, Hsiao E, Balakrishnar B, Lin P, Redfern A, Macdonald W, Ng S, Lee ST, Pattison DA, Nadebaum D, Kirkwood ID, Hofman MS, UpFrontPSMA Study Team. Sequential [177Lu]Lu-PSMA-617 and docetaxel versus docetaxel in patients with metastatic hormone-sensitive prostate cancer (UpFrontPSMA): a multicentre, open-label, randomised, phase 2 study. The Lancet. Oncology 2024. PMID: 39293461


  3. Qi L, Groeger M, Sharma A, Goswami I, Chen E, Zhong F, Ram A, Healy K, Hsiao EC, Willenbring H, Stahl A. Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system. Nature communications 2024. PMID: 39266553


  4. Hébert M, Babic K, Hsiao EC, Afshar A, Acharya N, Gonzales JA. Inhibition of choroidal osteoma progression using bisphosphonate and RANKL-inhibitory treatment. American journal of ophthalmology case reports 2024. PMID: 39314250


  5. Haviv R, Zeitlin L, Moshe V, Ziv A, Rabinowicz N, De Benedetti F, Prencipe G, Matteo V, De Cunto CL, Hsiao EC, Uziel Y. Long term use of interleukin-1 inhibitors reduce flare activity in patients with fibrodysplasia ossificans progressiva. Rheumatology (Oxford, England) 2024. PMID: 38733591


  6. Patel A, Dada A, Saggi S, Yamada H, Ambati VS, Goldstein E, Hsiao E, Mummaneni VP. Personalized Approaches to Spine Surgery. International journal of spine surgery 2024. PMID: 39191475


  7. Lounev V, Groppe JC, Brewer N, Wentworth KL, Smith V, Xu M, Schomburg L, Bhargava P, Al Mukaddam M, Hsiao EC, Shore EM, Pignolo RJ, Kaplan FS. MMP-9 deficiency confers resilience in Fibrodysplasia Ossificans Progressiva in a man and mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2024. PMID: 38477818


  8. Diolintzi A, Pervin MS, Hsiao EC. Immunologic Aspects in Fibrodysplasia Ossificans Progressiva. Biomolecules 2024. PMID: 38540775


  9. Juan C, Bancroft AC, Choi JH, Nunez JH, Pagani CA, Lin YS, Hsiao EC, Levi B. Intersections of Fibrodysplasia Ossificans Progressiva and Traumatic Heterotopic Ossification. Biomolecules 2024. PMID: 38540768


  10. Lung H, Wentworth KL, Moody T, Zamarioli A, Ram A, Ganesh G, Kang M, Ho S, Hsiao EC. Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone. JBMR plus 2024. PMID: 38577521


  11. Pignolo RJ, Al Mukaddam M, Baujat G, Brown MA, De Cunto C, Hsiao EC, Keen R, Le Quan Sang KH, Grogan DR, Marino R, Strahs AR, Kaplan FS. Study methodology and insights from the palovarotene clinical development program in fibrodysplasia ossificans progressiva. BMC medical research methodology 2023. PMID: 37957586


  12. Kazmi M, Zhang WR, Hsiao E, Gross A, Grouse K, Link TM, Tetzlaff M, Theodosopoulos P, Haemel A. Frontal bone loss following coronal brow lift: A mimicker of head variant linear morphea. JAAD case reports 2023. PMID: 37842147


  13. Groeger M, Matsuo K, Heidary Arash E, Pereira A, Le Guillou D, Pino C, Telles-Silva KA, Maher JJ, Hsiao EC, Willenbring H. Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages. Nature communications 2023. PMID: 37400454


  14. Apsel Winger B, Devine WP, Hsiao EC, Zapala M, Van Ziffle J, Gupta N, Frieden IJ, Shimano KA. EML4::ALK fusions in complex lymphatic malformations. Pediatric blood & cancer 2023. PMID: 37377128


  15. Niu I, Hsiao EC, Wustrack R, Wysolmerski JJ, Dann P, Masharani U. A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy. Calcified tissue international 2023. PMID: 37358786


  16. Chandran M, Alves I, Carpenter T, Davis M, Hsiao EC, Petryk A, Semler JO, Sleiman M. Improving care pathways for people living with rare bone diseases (RBDs): outcomes from the first RBD Summit. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2023. PMID: 37294334


  17. M. Al Mukaddam, G. Baujat, A.M. Cheung, C. De Cunto, E.C. Hsiao, R. Keen, J. Marden, J. Signorovitch, E. Boing, R. Marino, A. Strahs, R.J. Pignolo. CO32 Heterotopic Ossification in Palovarotene-Treated and Untreated Individuals with Fibrodysplasia Ossificans Progressiva: Matched and Weighted Analyses. Value in Health 2023. PMID:


  18. Lindborg CM, Al Mukaddam M, Baujat G, Cho TJ, De Cunto CL, Delai PLR, Eekhoff EMW, Haga N, Hsiao EC, Morhart R, de Ruiter R, Scott C, Seemann P, Szczepanek M, Tabarkiewicz J, Pignolo RJ, Kaplan FS. Most Fractures Treated Nonoperatively in Individuals With Fibrodysplasia Ossificans Progressiva Heal With a Paucity of Flareups, Heterotopic Ossification, and Loss of Mobility. Clinical orthopaedics and related research 2023. PMID: 37156007


  19. Qi L, Matsuo K, Pereira A, Lee YT, Zhong F, He Y, Zushin PH, Gr?ger M, Sharma A, Willenbring H, Hsiao EC, Stahl A. Human iPSC-Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System. Small (Weinheim an der Bergstrasse, Germany) 2023. PMID: 37104853


  21. Pignolo RJ, Hsiao EC, Al Mukaddam M, Baujat G, Berglund SK, Brown MA, Cheung AM, De Cunto C, Delai P, Haga N, Kannu P, Keen R, Le Quan Sang KH, Mancilla EE, Marino R, Strahs A, Kaplan FS. Reduction of New Heterotopic Ossification (HO) in the Open-Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP). Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022. PMID: 36583535


  22. Robert J Pignolo, Edward C Hsiao, Mona Al Mukaddam, Geneviève Baujat, Staffan K Berglund, Matthew A Brown, Angela M Cheung, Carmen De Cunto, Patricia Delai, Nobuhiko Haga, Peter Kannu, Richard Keen, Kim-Hanh Le Quan Sang, Edna E Mancilla, Rose Marino, Andrew Strahs, Frederick S Kaplan. The effects of palovarotene in patients with fibrodysplasia ossificans progressiva: a plain language summary. Future Rare Diseases 2023. PMID:


  23. Wentworth KL, Lalonde RL, Groppe JC, Brewer N, Moody T, Hansberry S, Taylor KE, Shore EM, Kaplan FS, Pignolo RJ, Yelick PC, Hsiao EC. Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1R206H -Specific Human Cellular and Zebrafish Models. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022. PMID: 36153796


  24. Isabella Niu, Edward Hsiao, Rosanna Wustrack, John Wysolmerski, Pamela Dann, Umesh Masharani. PSAT208 A Case of Hypercalcemia From PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy. Journal of the Endocrine Society 2022. PMID:


  25. Yang YS, Kim JM, Xie J, Chaugule S, Lin C, Ma H, Hsiao E, Hong J, Chun H, Shore EM, Kaplan FS, Gao G, Shim JH. Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery. Nature communications 2022. PMID: 36258013


  26. Pignolo RJ, Baujat G, Brown MA, De Cunto C, Hsiao EC, Keen R, Al Mukaddam M, Le Quan Sang KH, Wilson A, Marino R, Strahs A, Kaplan FS. The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study. Genetics in medicine : official journal of the American College of Medical Genetics 2022. PMID: 36152026


  27. Singh S, Morshed S, Motamedi D, Kidane J, Paul A, Hsiao EC, Wentworth KL. Identification of Risk Factors in the Development of Heterotopic Ossification after Primary Total Hip Arthroplasty. AACE Clinical Case Reports 2022. PMID: 35451005


  28. Pignolo RJ, Baujat G, Hsiao EC, Keen R, Wilson A, Packman J, Strahs AL, Grogan DR, Kaplan FS. Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022. PMID: 35854638


  29. Eekhoff EMW, de Ruiter RD, Smilde BJ, Schoenmaker T, Vries TJ, Netelenbos C, Hsiao EC, Scott C, Haga N, Grunwald Z, De Cunto CL, Di Rocco M, Delai P, Diecidue R, Madhuri V, Cho TJ, Morhart R, Friedman C, Zasloff M, Pals G, Shim JH, Gao G, Kaplan F, Pignolo RJ, Micha D. Gene therapy for Fibrodysplasia Ossificans Progressiva (FOP): feasibility and obstacles. AACE Clinical Case Reports 2022. PMID: 35502479


  30. Yu X, Ton AN, Niu Z, Morales BM, Chen J, Braz J, Lai MH, Barruet E, Liu H, Cheung K, Ali S, Chan T, Bigay K, Ho J, Nikolli I, Hansberry S, Wentworth K, Kriegstein A, Basbaum A, Hsiao EC. An ACVR1 activating mutation causes neuropathic pain and sensory neuron hyperexcitability in humans. AACE Clinical Case Reports 2022. PMID: 35442931


  31. Kou S, Kile S, Kambampati SS, Brady EC, Wallace H, De Sousa CM, Cheung K, Dickey L, Wentworth KL, Hsiao EC. Social and clinical impact of COVID-19 on patients with fibrodysplasia ossificans progressiva. AACE Clinical Case Reports 2022. PMID: 35246171


  32. Matsuo K, Lepinski A, Chavez RD, Barruet E, Pereira A, Moody TA, Ton AN, Sharma A, Hellman J, Tomoda K, Nakamura MC, Hsiao EC. Corrigendum to "ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages" [Bone. 153 2021 Dec; 116129. doi:10.1016/j.bone.2021.116129. Epub 2021 Jul 24. PMID: 34311122]. AACE Clinical Case Reports 2022. PMID: 35241401


  33. Quigley J, Sammel AM, Laurent R, Brewer J, Hsiao E, Schembri G, Fraser CL. The Clinical Significance of Small Vessel Vasculitis on Temporal Artery Biopsies. AACE Clinical Case Reports 2022. PMID: 35195542


  34. M Al Mukaddam, G Baujat, A Houchard, EC Hsiao, R Keen, R Marino, RJ Pignolo, FS Kaplan. POSC373 Use of Aids, Assistive Devices and Adaptations by Individuals with Fibrodysplasia Ossificans Progressiva (FOP): 36-Month Results from a Global Natural History Study. Value in Health 2022. PMID:


  35. Huppert LA, Hsu G, Elnachef N, Flint L, Frank JA, Gensler LS, Hsiao EC, Khanna RR, Qasim A, Schwartz BS, Widera E, Zapata C, Babik JM. A single center evaluation of applicant experiences in virtual interviews across eight internal medicine subspecialty fellowship programs. Medical education online 2021. PMID: 34187346


  36. de Ruiter RD, Smilde BJ, Pals G, Bravenboer N, Knaus P, Schoenmaker T, Botman E, Sánchez-Duffhues G, Pacifici M, Pignolo RJ, Shore EM, van Egmond M, Van Oosterwyck H, Kaplan FS, Hsiao EC, Yu PB, Bocciardi R, De Cunto CL, Longo Ribeiro Delai P, de Vries TJ, Hilderbrandt S, Jaspers RT, Keen R, Koolwijk P, Morhart R, Netelenbos JC, Rustemeyer T, Scott C, Stockklausner C, Ten Dijke P, Triffit J, Ventura F, Ravazzolo R, Micha D, Eekhoff EMW. Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop. AACE Clinical Case Reports 2021. PMID: 34858325


  37. Barruet E, Garcia SM, Wu J, Morales BM, Tamaki S, Moody T, Pomerantz JH, Hsiao EC. Modeling the ACVR1R206H mutation in human skeletal muscle stem cells. AACE Clinical Case Reports 2021. PMID: 34755602


  38. Kou S, Kile S, Kambampati SS, Brady EC, Wallace H, De Sousa CM, Cheung K, Dickey L, Wentworth KL, Hsiao E. Social and Clinical Impact of COVID-19 on Patients with Fibrodysplasia Ossificans Progressiva. Research square 2021. PMID: 34545360


  39. Pignolo RJ, Hsiao EC, Baujat G, Lapidus D, Sherman A, Kaplan FS. Prevalence of fibrodysplasia ossificans progressiva (FOP) in the United States: estimate from three treatment centers and a patient organization. Orphanet journal of rare diseases 2021. PMID: 34353327


  40. Warner SE, Kaplan FS, Pignolo RJ, Smith SE, Hsiao EC, De Cunto C, Di Rocco M, Harnett K, Grogan D, Genant HK. Whole-body Computed Tomography Versus Dual Energy X-ray Absorptiometry for Assessing Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva. Calcified tissue international 2021. PMID: 34331548


  41. Matsuo K, Lepinski A, Chavez RD, Barruet E, Pereira A, Moody TA, Ton AN, Sharma A, Hellman J, Tomoda K, Nakamura MC, Hsiao EC. ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages. Bone 2021. PMID: 34311122


  42. Kaplan FS, Teachey DT, Andolina JR, Siegel DM, Mancilla EE, Hsiao EC, Al Mukaddam M, Rocke DM, Pignolo RJ. Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva. Bone 2021. PMID: 34022457


  43. Hsuan Lung, Tania Moody, Kelly Wentworth, Misun Kang, Sunita Ho, Edward Hsiao. Global Wnt Inhibition With a Porcupine Inhibitor Decreases Established Trabecular Bone in a Mouse Model of Fibrous Dysplasia. Journal of the Endocrine Society 2021. PMID:


  44. Hofman MS, Emmett L, Sandhu S, Iravani A, Joshua AM, Goh JC, Pattison DA, Tan TH, Kirkwood ID, Ng S, Francis RJ, Gedye C, Rutherford NK, Weickhardt A, Scott AM, Lee ST, Kwan EM, Azad AA, Ramdave S, Redfern AD, Macdonald W, Guminski A, Hsiao E, Chua W, Lin P, Zhang AY, McJannett MM, Stockler MR, Violet JA, Williams SG, Martin AJ, Davis ID, TheraP Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials. [177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial. Lancet (London, England) 2021. PMID: 33581798


  46. M Al Mukaddam, C Stockklausner, RJ Pignolo, G Baujat, MA Brown, C De Cunto, M Di Rocco, EC Hsiao, R Keen, K-H Le Quan Sang, A Strahs, R Marino, FS Kaplan. A Global Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP): 12-Month Outcomes. Osteologie/Osteology 2021. PMID:


  47. RJ Pignolo, JO Semler, M Al Mukaddam, G Baujat, C De Cunto, EC Hsiao, R Keen, K Harnett, R Marino, FS Kaplan. Longitudinal and Flare-Up-Specific Biomarkers in Fibrodysplasia Ossificans Progressiva (FOP): Data from a Global Natural History Study. Osteologie/Osteology 2021. PMID:


  48. R Keen, C Stockklausner, M Al Mukaddam, G Baujat, C De Cunto, EC Hsiao, RJ Pignolo, K Harnett, R Marino, FS Kaplan. Medications Used by Individuals with Fibrodysplasia Ossificans Progressiva (FOP): Data from a Global Natural History Study. Osteologie/Osteology 2021. PMID:


  49. EC Hsiao, JO Semler, M Al Mukaddam, G Baujat, C De Cunto, R Keen, RJ Pignolo, K Harnett, R Marino, FS Kaplan. Use of Assistive Devices and Adaptations by Individuals with Fibrodysplasia Ossificans Progressiva (FOP): Data from a Global Natural History Study. Osteologie/Osteology 2021. PMID:


  50. Huppert LA, Hsiao EC, Cho KC, Marquez C, Chaudhry RI, Frank J, Goglin SE, Hsu G, Kathpalia P, Khanna R, Kompala T, Rao MN, Bower BA, Trafas V, Santhosh L, Schwartz BS, Babik JM. Virtual Interviews at Graduate Medical Education Training Programs: Determining Evidence-Based Best Practices. Academic medicine : journal of the Association of American Medical Colleges 2020. PMID: 33298691


  51. Robert J. Pignolo, Geneviève Baujat, Matthew A. Brown, Carmen De Cunto, Maja Di Rocco, Edward C. Hsiao, Richard Keen, Mona Al Mukaddam, Kim Hanh Le Quan Sang, Andrew Strahs, Rose Marino, Frederick S. Kaplan. A natural history study of fibrodysplasia ossificans progressiva (FOP): 12-month outcome results. Bone reports 2020. PMID:


  52. Robert J. Pignolo, Geneviève Baujat, Matthew A. Brown, Carmen De Cunto, Maja Di Rocco, Edward C. Hsiao, Richard Keen, Mona Al Mukaddam, Andrew Strahs, Donna R. Grogan, Rose Marino, Frederick S. Kaplan. Measuring outcomes in ultra-rare bone diseases: Methodology of the palovarotene fibrodysplasia ossificans progressiva clinical development programme. Bone reports 2020. PMID:


  53. Mona Al Mukaddam, Robert J. Pignolo, Geneviève Baujat, Matthew A Brown, Cunto Carmen De, Rocco Maja Di, Edward C. Hsiao, Richard Keen, Quan Sang Kim-Hanh Le, Andrew Strahs, Rose Marino, Frederick S Kaplan. A global natural history study of Fibrodysplasia Ossificans Progressiva (FOP): 12-month outcomes. Endocrine Abstracts 2020. PMID:


  54. Kou S, De Cunto C, Baujat G, Wentworth KL, Grogan DR, Brown MA, Di Rocco M, Keen R, Al Mukaddam M, le Quan Sang KH, Masharani U, Kaplan FS, Pignolo RJ, Hsiao EC. Patients with ACVR1R206H mutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of Fibrodysplasia Ossificans Progressiva. Orphanet journal of rare diseases 2020. PMID: 32727600


  55. Sukhmani Singh, Joseph Kidane, Kelly Lee Wentworth, Daria Motamedi, Saam Morshed, Edward Chiaming Hsiao. MON-348 Surgical Management of Bilateral Hip Fracture in a Patient with Fibrodysplasia Ossificans Progressiva Treated with Palovarotene. Journal of the Endocrine Society 2020. PMID:


  56. Emilie Barruet, Steven Garcia, Stanley Tamaki, Blanca M Morales, Jake Wu, Tania Moody, Jason H Pomerantz, Edward Chiaming Hsiao. MON-710 ACVR1 Activation in Primary and iPS-Derived Human Skeletal Muscle Stem Cells Impairs Myogenic Transcriptional Signature and Function. Journal of the Endocrine Society 2020. PMID:


  57. Mona Al Mukaddam, Robert J Pignolo, Geneviève Baujat, Matthew A Brown, Carmen De Cunto, Maja Di Rocco, Edward C Hsiao, Richard W Keen, Kim-Hanh Le Quan Sang, Andrew Strahs, Rose Marino, Frederick S Kaplan. OR29-05 A Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP): 12-Month Outcomes. Journal of the Endocrine Society 2020. PMID:


  58. Samuel Kou, Carmen DeCunto, Geneviève Baujat, Kelly Lee Wentworth, Donna Grogan, Matthew A Brown, Maja D Rocco, Richard Keen, Mona Al Mukaddam, Frederick S Kaplan, Robert J Pignolo, Edward Chiaming Hsiao. SUN-344 Patients with Fibrodysplasia Ossificans Progressiva Have an Increased Prevalence of Cardiac Conduction Abnormalities. Journal of the Endocrine Society 2020. PMID:


  59. Hsuan Lung, Kelly Wentworth, Tania Moody, Misun Kang, Sunita Ho, Edward Hsiao. SUN-368 Wnt Inhibition Decreases Trabecular Bone in a Mouse Model of Fibrous Dysplasia. Journal of the Endocrine Society 2020. PMID:


  60. Singh S, Kidane J, Wentworth KL, Motamedi D, Morshed S, Schober AE, Hsiao EC. Surgical management of bilateral hip fractures in a patient with fibrodysplasia ossificans progressiva treated with the RAR-? agonist palovarotene: a case report. BMC musculoskeletal disorders 2020. PMID: 32245464


  61. Pignolo RJ, Cheung K, Kile S, Fitzpatrick MA, De Cunto C, Al Mukaddam M, Hsiao EC, Baujat G, Delai P, Eekhoff EMW, Di Rocco M, Grunwald Z, Haga N, Keen R, Levi B, Morhart R, Scott C, Sherman A, Zhang K, Kaplan FS. Self-reported baseline phenotypes from the International Fibrodysplasia Ossificans Progressiva (FOP) Association Global Registry. Bone 2020. PMID: 32062004


  62. Lung H, Hsiao EC, Wentworth KL. Advances in Models of Fibrous Dysplasia/McCune-Albright Syndrome. Frontiers in endocrinology 2020. PMID: 32038487


  63. Matsuo K, Chavez RD, Barruet E, Hsiao EC. Inflammation in Fibrodysplasia Ossificans Progressiva and Other Forms of Heterotopic Ossification. Current osteoporosis reports 2019. PMID: 31721068


  64. Frederick Kaplan, Edward C Hsiao, Genevieve Baujat, Richard Keen, Cunto Carmen De, Rocco Maja Di, Matthew A Brown, Mukaddam Mona M Al, Donna R Grogan, Robert J Pignolo. Palovarotene inhibits the development of new heterotopic ossification in fibrodysplasia ossificans progressiva (FOP). Bone Abstracts 2019. PMID:


  65. Pignolo RJ, Baujat G, Brown MA, De Cunto C, Di Rocco M, Hsiao EC, Keen R, Al Mukaddam M, Sang KLQ, Wilson A, White B, Grogan DR, Kaplan FS. Correction to: Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes. Orphanet journal of rare diseases 2019. PMID: 31122250


  66. Pignolo RJ, Baujat G, Brown MA, De Cunto C, Di Rocco M, Hsiao EC, Keen R, Al Mukaddam M, Sang KLQ, Wilson A, White B, Grogan DR, Kaplan FS. Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes. Orphanet journal of rare diseases 2019. PMID: 31053156


  67. Pennings I, van Dijk LA, van Huuksloot J, Fledderus JO, Schepers K, Braat AK, Hsiao EC, Barruet E, Morales BM, Verhaar MC, Rosenberg AJWP, Gawlitta D. Effect of donor variation on osteogenesis and vasculogenesis in hydrogel cocultures. Journal of tissue engineering and regenerative medicine 2019. PMID: 30650247


  68. Back M, Jayamanne DT, Brazier D, Newey A, Bailey D, Schembri GP, Hsiao E, Khasraw M, Wong M, Kastelan M, Guo L, Clarke S, Wheeler H. Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management. Journal of medical imaging and radiation oncology 2019. PMID: 30677248


  69. Wentworth KL, Masharani U, Hsiao EC. Therapeutic advances for blocking heterotopic ossification in fibrodysplasia ossificans progressiva. British journal of clinical pharmacology 2018. PMID: 30501012


  70. Barruet E, Morales BM, Cain CJ, Ton AN, Wentworth KL, Chan TV, Moody TA, Haks MC, Ottenhoff TH, Hellman J, Nakamura MC, Hsiao EC. NF-?B/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification. JCI insight 2018. PMID: 30429363


  71. Hsiao EC, Di Rocco M, Cali A, Zasloff M, Al Mukaddam M, Pignolo RJ, Grunwald Z, Netelenbos C, Keen R, Baujat G, Brown MA, Cho TJ, De Cunto C, Delai P, Haga N, Morhart R, Scott C, Zhang K, Diecidue RJ, Friedman CS, Kaplan FS, Eekhoff EMW. Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP). British journal of clinical pharmacology 2018. PMID: 30281842


  72. Chan DL, Hsiao E, Schembri G, Bailey DL, Roach PJ, Lee A, Jayamanne D, Ghasemzadeh M, Hayes A, Cook R, Parkinson J, Drummond JP, Ibbett I, Wheeler HR, Back M. FET PET in the evaluation of indeterminate brain lesions on MRI: Differentiating glioma from other non-neoplastic causes - A pilot study. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2018. PMID: 30243602


  73. Gild ML, Naik N, Hoang J, Hsiao E, McGrath RT, Sywak M, Sidhu S, Delbridge LW, Robinson BG, Schembri G, Clifton-Bligh RJ. Role of DOTATATE-PET/CT in preoperative assessment of phaeochromocytoma and paragangliomas. Clinical endocrinology 2018. PMID: 29741215


  74. Hruby G, Eade T, Emmett L, Ho B, Hsiao E, Schembri G, Guo L, Kwong C, Hunter J, Byrne K, Kneebone A. 68 Ga-PSMA-PET/CT staging prior to definitive radiation treatment for prostate cancer. Asia-Pacific journal of clinical oncology 2018. PMID: 29663686


  75. Bauer AH, Bonham J, Gutierrez L, Hsiao EC, Motamedi D. Fibrodysplasia ossificans progressiva: a current review of imaging findings. Skeletal radiology 2018. PMID: 29445932


  76. Wentworth KL, Bigay K, Chan TV, Ho JP, Morales BM, Connor J, Brooks E, Shahriar Salamat M, Sanchez HC, Wool G, Pignolo RJ, Kaplan FS, Hsiao EC. Clinical-pathological correlations in three patients with fibrodysplasia ossificans progressiva. Bone 2017. PMID: 29033382


  77. Ho L, Wang L, Roth TM, Pan Y, Verdin EM, Hsiao EC, Nissenson RA. Sirtuin-3 Promotes Adipogenesis, Osteoclastogenesis, and Bone Loss in Aging Male Mice. Endocrinology 2017. PMID: 28911171


  78. Mantick N, Bachman E, Baujat G, Brown M, Collins O, De Cunto C, Delai P, Eekhoff M, Zum Felde R, Grogan DR, Haga N, Hsiao E, Kantanie S, Kaplan F, Keen R, Milosevic J, Morhart R, Pignolo R, Qian X, di Rocco M, Scott C, Sherman A, Wallace M, Williams N, Zhang K, Bogard B. The FOP Connection Registry: Design of an international patient-sponsored registry for Fibrodysplasia Ossificans Progressiva. Bone 2017. PMID: 28866367


  79. Kaplan FS, Andolina JR, Adamson PC, Teachey DT, Finklestein JZ, Ebb DH, Whitehead B, Jacobs B, Siegel DM, Keen R, Hsiao E, Pignolo RJ. Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases. Bone 2017. PMID: 28736245


  81. Frederick S Kaplan, Edward C Hsiao, Genevieve Baujat, Matthew A Brown, Cunto Carmen De, Rocco Maja Di, Richard Keen, Makkadam Mona Al, Donna R Grogan, Robert J Pignolo. Fibrodysplasia ossificans progressiva: baseline characteristics of 101 subjects participating in a global, longitudinal, natural history study. Bone Abstracts 2017. PMID:


  82. Roach PJ, Francis R, Emmett L, Hsiao E, Kneebone A, Hruby G, Eade T, Nguyen QA, Thompson BD, Cusick T, McCarthy M, Tang C, Ho B, Stricker PD, Scott AM. The Impact of 68Ga-PSMA PET/CT on Management Intent in Prostate Cancer: Results of an Australian Prospective Multicenter Study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017. PMID: 28646014


  83. Kanthan GL, Hsiao E, Vu D, Schembri GP. Uptake in sympathetic ganglia on 68 Ga-PSMA-HBED PET/CT: A potential pitfall in scan interpretation. Journal of medical imaging and radiation oncology 2017. PMID: 28623872


  84. Di Rocco M, Baujat G, Bertamino M, Brown M, De Cunto CL, Delai PLR, Eekhoff EMW, Haga N, Hsiao E, Keen R, Morhart R, Pignolo RJ, Kaplan FS. International physician survey on management of FOP: a modified Delphi study. Orphanet journal of rare diseases 2017. PMID: 28606101


  85. Schmitt CE, Morales BM, Schmitz EMH, Hawkins JS, Lizama CO, Zape JP, Hsiao EC, Zovein AC. Fluorescent tagged episomals for stoichiometric induced pluripotent stem cell reprogramming. Stem cell research & therapy 2017. PMID: 28583172


  86. Chan M, Hsiao E, Turner J. Cerebellar Metastases From Prostate Cancer on 68Ga-PSMA PET/CT. Clinical nuclear medicine 2017. PMID: 28033225


  87. Chan DL, Pavlakis N, Schembri GP, Bernard EJ, Hsiao E, Hayes A, Barnes T, Diakos C, Khasraw M, Samra J, Eslick E, Roach PJ, Engel A, Clarke SJ, Bailey DL. Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: Proposal for a Novel Grading Scheme with Prognostic Significance. Theranostics 2017. PMID: 28435454


  88. Chan M, Hsiao E. Neurosarcoidosis on FET and FDG PET/CT. Clinical nuclear medicine 2017. PMID: 28045730


  89. Niethamer TK, Larson AR, O'Neill AK, Bershteyn M, Hsiao EC, Klein OD, Pomerantz JH, Bush JO. EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells. Stem cell reports 2017. PMID: 28238796


  90. Chan M, Hsiao E. Subacute Cortical Infarct Showing Uptake on 68Ga-PSMA PET/CT. Clinical nuclear medicine 2017. PMID: 27997426


  92. Chan M, Schembri GP, Hsiao E. Serous Cystadenoma of the Pancreas Showing Uptake on 68Ga PSMA PET/CT. Clinical nuclear medicine 2017. PMID: 27764044


  93. Hruby G, Eade T, Kneebone A, Emmett L, Guo L, Ho B, Hsiao E, Schembri G, Hunter J, Kwong C. Delineating biochemical failure with 68Ga-PSMA-PET following definitive external beam radiation treatment for prostate cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2016. PMID: 28040309


  95. Hayashi Y, Hsiao EC, Sami S, Lancero M, Schlieve CR, Nguyen T, Yano K, Nagahashi A, Ikeya M, Matsumoto Y, Nishimura K, Fukuda A, Hisatake K, Tomoda K, Asaka I, Toguchida J, Conklin BR, Yamanaka S. BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. Proceedings of the National Academy of Sciences of the United States of America 2016. PMID: 27794120


  96. Hsiao EC, Millard SM, Nissenson RA. Gs/Gi Regulation of Bone Cell Differentiation: Review and Insights from Engineered Receptors. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2016. PMID: 27643449


  97. Kanthan GL, Izard MA, Emmett L, Hsiao E, Schembri GP. Schwannoma Showing Avid Uptake on 68Ga-PSMA-HBED-CC PET/CT. Clinical nuclear medicine 2016. PMID: 27405039


  98. Barruet E, Morales BM, Lwin W, White MP, Theodoris CV, Kim H, Urrutia A, Wong SA, Srivastava D, Hsiao EC. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling. Stem cell research & therapy 2016. PMID: 27530160


  99. Wentworth K, Hsing A, Urrutia A, Zhu Y, Horvai AE, Bastepe M, Hsiao EC. A Novel T55A Variant of Gs a Associated with Impaired cAMP Production, Bone Fragility, and Osteolysis. Case reports in endocrinology 2016. PMID: 27579188


  100. Kanthan GL, Schembri GP, Samra J, Roach P, Hsiao E. Metastatic Renal Cell Carcinoma in the Thyroid Gland and Pancreas Showing Uptake on 68Ga DOTATATE PET/CT Scan. Clinical nuclear medicine 2016. PMID: 27055137


  101. Kanthan GL, Hsiao E, Kneebone A, Eade T, Schembri GP. Desmoid Tumor Showing Intense Uptake on 68Ga PSMA-HBED-CC PET/CT. Clinical nuclear medicine 2016. PMID: 26909712


  102. Kanthan GL, Coyle L, Kneebone A, Schembri GP, Hsiao E. Follicular Lymphoma Showing Avid Uptake on 68Ga PSMA-HBED-CC PET/CT. Clinical nuclear medicine 2016. PMID: 26914565


  103. Cain CJ, Gaborit N, Lwin W, Barruet E, Ho S, Bonnard C, Hamamy H, Shboul M, Reversade B, Kayserili H, Bruneau BG, Hsiao EC. Loss of Iroquois homeobox transcription factors 3 and 5 in osteoblasts disrupts cranial mineralization. Bone reports 2016. PMID: 27453922


  104. Kanthan GL, Drummond J, Schembri GP, Izard MA, Hsiao E. Follicular Thyroid Adenoma Showing Avid Uptake on 68Ga PSMA-HBED-CC PET/CT. Clinical nuclear medicine 2016. PMID: 26646999


  105. Cain CJ, Valencia JT, Ho S, Jordan K, Mattingly A, Morales BM, Hsiao EC. Increased Gs Signaling in Osteoblasts Reduces Bone Marrow and Whole-Body Adiposity in Male Mice. Endocrinology 2016. PMID: 26901092


  106. Barruet E, Hsiao EC. Using Human Induced Pluripotent Stem Cells to Model Skeletal Diseases. Methods in molecular biology (Clifton, N.J.) 2016. PMID: 25549831


  107. Hindi SM, Wang Y, Jones KD, Nussbaum JC, Chang Y, Masharani U, Bikle D, Shoback DM, Hsiao EC. A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting. Volume 97 of Issue 6. 2015. PMID: 26253396


  108. Shah AD, Hsiao EC, O'Donnell B, Salmeen K, Nussbaum R, Krebs M, Baumgartner-Parzer S, Kaufmann M, Jones G, Bikle DD, Wang Y, Mathew AS, Shoback D, Block-Kurbisch I. Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations. Volume 100 of Issue 8. 2015. PMID: 26097993


  109. Wang L, Hsiao EC, Lieu S, Scott M, O'Carroll D, Urrutia A, Conklin BR, Colnot C, Nissenson RA. Loss of Gi G-Protein-Coupled Receptor Signaling in Osteoblasts Accelerates Bone Fracture Healing. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015. PMID: 25917236


  110. Hong CW, Hsiao EC, Horvai AE, Link TM. Chronic recurrent multifocal osteomyelitis with an atypical presentation in an adult man. Skeletal radiology 2015. PMID: 25771734


  111. Wattanachanya L, Wang L, Millard SM, Lu WD, O'Carroll D, Hsiao EC, Conklin BR, Nissenson RA. Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs-G protein signaling in osteoblasts. Experimental cell research 2015. PMID: 25704759


  112. Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu GQ, Adame A, Devidze N, Dubal DB, Masliah E, Conklin BR, Mucke L. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nature neuroscience 2015. PMID: 25622143


  113. Akil O, Hall-Glenn F, Chang J, Li A, Chang W, Lustig LR, Alliston T, Hsiao EC. Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia. PloS one 2014. PMID: 24788917


  114. Schafer AL, Mumm S, El-Sayed I, McAlister WH, Horvai AE, Tom AM, Hsiao EC, Schaefer FV, Collins MT, Anderson MS, Whyte MP, Shoback DM. Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK. Volume 29 of Issue 4. 2014. PMID: 24014458


  115. Bershteyn M, Hayashi Y, Desachy G, Hsiao EC, Sami S, Tsang KM, Weiss LA, Kriegstein AR, Yamanaka S, Wynshaw-Boris A. Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature 2014. PMID: 24413397


  116. Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC. Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet journal of rare diseases 2013. PMID: 24321451


  117. Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell stem cell 2013. PMID: 23850243


  118. Spindler MJ, Burmeister BT, Huang Y, Hsiao EC, Salomonis N, Scott MJ, Srivastava D, Carnegie GK, Conklin BR. AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to ß-adrenergic-induced cardiac hypertrophy. PloS one 2013. PMID: 23658642


  119. Schepers K, Hsiao EC, Garg T, Scott MJ, Passegué E. Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice. Blood 2012. PMID: 22859604


  120. Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC. Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor. Calcified tissue international 2011. PMID: 21526395


  121. Hsiao EC, Nguyen TD, Ng JK, Scott MJ, Chang WC, Zahed H, Conklin BR. Constitutive Gs activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice. Stem cell research & therapy 2011. PMID: 21375737


  122. van Laake LW, Qian L, Cheng P, Huang Y, Hsiao EC, Conklin BR, Srivastava D. Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circulation research 2010. PMID: 20558827


  123. Hsiao EC, Boudignon BM, Halloran BP, Nissenson RA, Conklin BR. Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010. PMID: 20200944


  124. Hsiao EC, Millard SM, Louie A, Huang Y, Conklin BR, Nissenson RA. Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation. Molecular endocrinology (Baltimore, Md.) 2010. PMID: 20150184


  125. Ali B, Hsiao E, Di Carli MF. Combined anatomic and perfusion imaging of the heart. Current cardiology reports 2010. PMID: 20425189


  126. Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL. Engineering GPCR signaling pathways with RASSLs. Nature methods 2008. PMID: 18668035


  127. Hsiao EC, Yoshinaga Y, Nguyen TD, Musone SL, Kim JE, Swinton P, Espineda I, Manalac C, deJong PJ, Conklin BR. Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter. PloS one 2008. PMID: 18596956


  128. Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell stem cell 2008. PMID: 18371447


  129. Hsiao EC, Boudignon BM, Chang WC, Bencsik M, Peng J, Nguyen TD, Manalac C, Halloran BP, Conklin BR, Nissenson RA. Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass. Proceedings of the National Academy of Sciences of the United States of America 2008. PMID: 18212126


  130. Chang WC, Ng JK, Nguyen T, Pellissier L, Claeysen S, Hsiao EC, Conklin BR. Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor. PloS one 2007. PMID: 18338032


  131. Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D. Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proceedings of the National Academy of Sciences of the United States of America 2007. PMID: 17576928


  132. Peter Chang, Edward Hsiao, Alex C Zambon, Bruce R Conklin. A Series of RASSLs Activated by a Single Agonist. The FASEB Journal 2006. PMID:


  133. Stretch JR, Somorjai R, Bourne R, Hsiao E, Scolyer RA, Dolenko B, Thompson JF, Mountford CE, Lean CL. Melanoma metastases in regional lymph nodes are accurately detected by proton magnetic resonance spectroscopy of fine-needle aspirate biopsy samples. Annals of surgical oncology 2005. PMID: 16177860


  134. Zimmers TA, Jin X, Hsiao EC, Perez EA, Pierce RH, Chavin KD, Koniaris LG. Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms. The Journal of surgical research 2005. PMID: 16154591


  135. Hsiao E, Charles R, Magid C, Nivatpumin P, Wiener CM. An unusual development. The American journal of medicine 2005. PMID: 15922691


  136. Zimmers TA, Jin X, Hsiao EC, McGrath SA, Esquela AF, Koniaris LG. Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury. Shock (Augusta, Ga.) 2005. PMID: 15897808


  137. Nakakura EK, Sriuranpong VR, Kunnimalaiyaan M, Hsiao EC, Schuebel KE, Borges MW, Jin N, Collins BJ, Nelkin BD, Chen H, Ball DW. Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling. The Journal of clinical endocrinology and metabolism 2005. PMID: 15870121


  138. Hsiao E, Huynh T, Mansberg R, Bautovich G, Roach P. Diagnostic I-123 scintigraphy to assess potential breast uptake of I-131 before radioiodine therapy in a postpartum woman with thyroid cancer. Clinical nuclear medicine 2004. PMID: 15249829


  139. Maruthur NM, Hsiao EC, Lee J, Nivatpumin P. Cases from the Osler medical service at Johns Hopkins University. The American journal of medicine 2004. PMID: 15047040


  140. Huynh T, Mansberg R, Hsiao E, Coyle L, Roach P. Transient absence of hepatic uptake on gallium-67 scintigraphy following fludarabine therapy. Clinical nuclear medicine 2004. PMID: 15096981


  141. Hsiao E, Mansberg R, Huynh T, Roach P. Pericarditis associated with cryptococcal meningitis on Ga-67 scintigraphy. Clinical nuclear medicine 2004. PMID: 14734914


  142. Koniaris LG, Zimmers-Koniaris T, Hsiao EC, Chavin K, Sitzmann JV, Farber JM. Cytokine-responsive gene-2/IFN-inducible protein-10 expression in multiple models of liver and bile duct injury suggests a role in tissue regeneration. Journal of immunology (Baltimore, Md. : 1950) 2001. PMID: 11418676


  143. Hsiao EC, Koniaris LG, Zimmers-Koniaris T, Sebald SM, Huynh TV, Lee SJ. Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury. Molecular and cellular biology 2000. PMID: 10779363


  144. Hertel KJ, Lynch KW, Hsiao EC, Liu EH, Maniatis T. Structural and functional conservation of the Drosophila doublesex splicing enhancer repeat elements. RNA (New York, N.Y.) 1996. PMID: 8849774