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Faculty Profiles

Michael German, MD

Professor

Michael.German@ucsf.edu

Dr. German is a Professor in the Department of Medicine, Clinical Director of the UCSF Diabetes Center, Director of the UCSF NIH Diabetes Research Center (DRC), Hillblom Islet Genesis Network and UCSF Diabetes, Endocrinology and Metabolism Fellowship Training Program, and Principle Investigator in the Hormone Research Institute and the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research. He cares for patients in the Diabetes Clinic and hospital wards, teaches medical students and housestaff, and lectures at the Diabetes Center's patient self-management courses. His group studies the formation and function of the insulin-producing beta-cells in the pancreas, how these processes break down in diabetes, hypoglycemia and pancreatic neuroendocrine tumors, and the translation of this knowledge into novel therapeutic strategies for these disorders.

Awards and Honors

2016   Josiah Brown Professorship, University of California Los Angeles, 2016
2016   Albert Renold Prize, European Association for the Study of Diabetes, 2016
2016   Albert Weinstein Lectureship, Vanderbilt University, 2016
2016   Arthur Riggs Award, Rachmiel Levine-Arthur Riggs Diabetes Research Symposium, 2016
2013   Gerold Grodsky Award, Western Regional Islet Study Group, 2013
2011   Donald F. Steiner Award for Outstanding Achievement in Diabetes Research, University of Chicago, 2011
2010   Arnold Lazarow Memorial Lecture, University of Minnesota Medical School, 2010
2009   Alexander Marble Lectureship, Joslin Diabetes Center, Harvard University Medical School, 2009
2009   Pfizer Visiting Professorship, University of Texas Health Science Center at Houston, 2009
2008   David Rumbough Award for Scientific Excellence, Juvenile Diabetes Research Foundation, 2008
2007   Scholars Award, Juvenile Diabetes Research Foundation, 2007
2006   Haile T. Debas Academy of Medical Educators Excellence in Teaching Award, UCSF, 2006

Recent Articles (10)

Tang SC, Baeyens L, Shen CN, Peng SJ, Chien HJ, Scheel DW, Chamberlain CE, German MS. Human pancreatic neuro-insular network in health and fatty infiltration. Diabetologia. 2017 Aug 29.

Lazo-de-la-Vega-Monroy ML, Larrieta E, Tixi-Verdugo W, Ramírez-Mondragón R, Hernández-Araiza I, German MS, Fernandez-Mejia C. Effects of dietary biotin supplementation on glucagon production, secretion, and action. Nutrition. 2017 Nov - Dec; 43-44:47-53.

Krentz NAJ, van Hoof D, Li Z, Watanabe A, Tang M, Nian C, German MS, Lynn FC. Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors. Dev Cell. 2017 Apr 24; 41(2):129-142.e6.

Pappalardo Z, Gambhir Chopra D, Hennings TG, Richards H, Choe J, Yang K, Baeyens L, Ang K, Chen S, Arkin M, German MS, McManus MT, Ku GM. A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response. Diabetes. 2017 Jun; 66(6):1703-1712.

Baeyens L, Hindi S, Sorenson RL, German MS. ß-Cell adaptation in pregnancy. Diabetes Obes Metab. 2016 Sep; 18 Suppl 1:63-70.

Stock PG, German MS. A Path to Insulin Independence: "The End of the Beginning". Cell Stem Cell. 2016 Apr 07; 18(4):431-3.

Ejarque M, Mir-Coll J, Gomis R, German MS, Lynn FC, Gasa R. Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8). PLoS One. 2016; 11(1):e0146273.

Sasaki S, Miyatsuka T, Matsuoka TA, Takahara M, Yamamoto Y, Yasuda T, Kaneto H, Fujitani Y, German MS, Akiyama H, Watada H, Shimomura I. Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice. Diabetologia. 2015 Nov; 58(11):2582-91.

Faire M, Skillern A, Arora R, Nguyen DH, Wang J, Chamberlain C, German MS, Fung JC, Laird DJ. Follicle dynamics and global organization in the intact mouse ovary. Dev Biol. 2015 Jul 01; 403(1):69-79.

Berger M, Scheel DW, Macias H, Miyatsuka T, Kim H, Hoang P, Ku GM, Honig G, Liou A, Tang Y, Regard JB, Sharifnia P, Yu L, Wang J, Coughlin SR, Conklin BR, Deneris ES, Tecott LH, German MS. Gai/o-coupled receptor signaling restricts pancreatic ß-cell expansion. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):2888-93.

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